Use of microcalorimetry in monitoring stability studies. Example: Vitamin A esters

Journal of Agricultural and Food Chemistry

Volumn 48, Issue 1, 2000, Pages 47-55

  Runge, Frank E ^a   Heger, Robert ^a  

^a BASF SE   (Germany)

Author keywords

Kitols; Microcalorimetry; Supercritical fluid chromatography; Vitamin A stability

Indexed keywords

CAROTENOID; DRUG DERIVATIVE; OLIGOMER; RETINOL; RETINOL ACETATE; RETINOL ESTER; RETINOL PALMITATE;

ARTICLE; CALORIMETRY; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DRUG DEGRADATION; DRUG STABILITY; DRUG STRUCTURE; KITOL; MICROCALORIMETRY; MODEL; PREDICTION; SUPERCRITICAL FLUID CHROMATOGRAPHY; THERMODYNAMICS;

CALORIMETRY; CAROTENOIDS; MODELS, CHEMICAL; VITAMIN A;

EID: 0033968233     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf981163y     Document Type: Article

References (21)

1. 1H NMR-Kopplung. Angew. Chem. 1995, 107, 1102-1104.
2. Ammo, T.; Washitake, M.; Takashima, Y.; Sato, S. Stability of vitamin A. II. Change rate and its process of vitamin A acetate in aqueous ethanolic solution. Bitamin 1968, 37, 19-24.
3. Atkins, P. W. The rates of chemical reactions. In Physical Chemistry, 4th ed.; Freeman, Oxford University Press: New York, 1990.
4. Buckton, G. Applications of isothermal microcalorimetry in the pharmaceutical sciences. Thermochim. Acta 1995, 248, 117-129.
5. Burger, B. V.; Garbers, C. F. Diels-Alder reactions. Part III. Condensation of Methyl trans-β-formylcrotonate with retinol acetate, with a note on the structure and stereochemistry of kitol. J. Chem. Soc., Perkin Trans. 1 1973, 590-595.
6. Chaundy, F. K.; Bower, D. K.; Kilbride, T. K. Process for incorporation a material in a cross-linked gelatin, and product therefrom. U.S. Patent 5153177, 1991.
7. Das, K. K. Preparation of kitol acetate from retinyl acetate by the action of indirect sunlight. Indian J. Chem. 1974, 12, 1216.
8. Fukamachi, C.; Schumacher, H.; Bewert, W.; Schneider, J. Stabiles Gemisch mit einem Gehalt oxidationsempfindlicher Verbindungen. Eur. Patent 0326026, 1989.
9. Giannotti, C.; Das, B. C.; Lederer, E. Sur la constitution chimique du kitol, dimère de la vitamine A. Bull. Soc. Chim. Fr. 1966, 3299-3303.
10. Koenigbauer, M. J.; Brooks, S. H.; Rullo, G.; Couch, R. A. Solid-state stability testing of drugs by isothermal calorimetry. Pharm. Res. 1992, 9, 939-944.
11. Laohasongkram, K.; Thamjariyapan, S. Kinetics of vitamin A degradation in pork liver puree during heat processing. Cell Biol. Int. 1995, 19, 229-236.
12. Lundgren, R.; Sandén, R. A facile method for the study of slow physical and chemical processes in polymeric systems. J. Appl. Polym. Sci. 1989, 37, 1221-1231.
13. Mousseron-Canet, M.; Lerner, D.; Mani, J.-C. Structure d'un photodimère de la vitamine A. Bull. Soc. Chim. Fr. 1968, 4639-4645.
14. Ottaway, P. B. Stability of vitamins in food. In The Technology of Vitamins in Food; Ottaway, P. B., Ed.; Blackie Academic & Professional: London, U.K., 1993.
15. Paquette, G.; Kanaan, A. M. Degradation of retinyl acetate in simple solvent systems. Food Chem. 1985, 18, 211-231.
16. Pfoertner, K-H.; Englert, G.; Schoenholzer, P. Photosensitized [4+2] cyclodimerizations of aromatic retinoids. Tetrahedron 1988, 44, 1039-1052.
17. Schlotterbeck, G.; Tseng, L.-H.; Händel, H.; Braumann, U.; Albert, K. Direct on-line coupling of capillary HPLC with 1H NMR spectroscopy for the structural determination of retinyl acetate dimers: 2D NMR spectroscopy in the nanoliter scale. Anal. Chem. 1997, 69, 1421-1425.
18. Schumacher, H.; Grafen, P. Verfahren zur Herstellung von Trockenpulvern oxidationsempfindlicher Substanzen. Eur. Patent 0074050, 1982.
19. Shah, R. C.; Raman, P. V.; Shah, B. M.; Vora, H. H. Accelerated tests in relation to shelf life of multivitamin liquid preparations. Drug Dev. Commun. 1976, 2, 393-403.
20. Suurkuusk, J.; Wadsö, I. A multichannel microcalorimetry system. Chem. Scr. 1982, 20, 155-163.
21. Yoshioka, S.; Aso, Y.; Takeda, Y. Isothermal and nonisothermal kinetics in the stability prediction of vitamin A preparations. Pharm. Res. 1990, 7, 388-391.