Prostaglandin E2 (PGE2) induces the c-fos and c-jun expressions via the EP1 subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells

Calcified Tissue International

Volumn 66, Issue 3, 2000, Pages 217-223

  Suda, M ^a   Tanaka, K ^a   Sakuma, Y ^a   Yasoda, A ^a   Ozasa, A ^a   Fukata, J ^a   Tanaka, I ^a   Narumiya, S ^a   Nakao, K ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

C fos; C jun; MC3T3 E1 cells; Prostaglandin E receptor; Prostaglandin E2

Indexed keywords

11 DEOXYPROSTAGLANDIN E1; ALKALINE PHOSPHATASE; ANTISENSE OLIGONUCLEOTIDE; BUTAPROST; MESSENGER RNA; OSTEOCALCIN; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; PROSTAGLANDIN E2 DERIVATIVE; PROSTAGLANDIN SYNTHASE; PROTEIN C FOS; PROTEIN C JUN; RECEPTOR SUBTYPE; SULPROSTONE;

ANIMAL CELL; ARTICLE; BONE MATRIX; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG POTENCY; GENE EXPRESSION; GENE INDUCTION; MOUSE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; OSTEOBLAST; PRIORITY JOURNAL; PROTO ONCOGENE;

ALKALINE PHOSPHATASE; ANIMALS; CELL LINE; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GENES, FOS; GENES, JUN; ISOENZYMES; MICE; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; OSTEOBLASTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, PROSTAGLANDIN E; RNA, MESSENGER;

EID: 0033968072     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002230010043     Document Type: Article

References (28)

1. Pilbeam CC, Harrison JR, Raisz LG (1996) Prostaglandins and bone metabolism. In: Bilezikian JP, Raisz LG, Rodan GA (eds) Principles of bone biology. Academic Press, San Diego, pp 715-728
2. Klein DC, Raisz LG (1970) Prostaglandin: stimulation of bone resorption in tissue culture. Endocrinology 86:1436-1440
3. 2 in growing rats: metaphyseal hard tissue and cortico-endosteal bone formation. Calcif Tissue Int 37:148-157
4. 1 administration. J Pediatr 97:866-867
5. 2. Biochem Biophys Res Commun 102:1358-1365
6. Hakeda Y, Natakani Y, Hiramatsu M, Kurihara N, Tsunoi M, Ikeda E, Kumegawa M (1985) Inductive effects of prostaglandins on alkaline phosphatase in osteoblastic cells, clone MC3T3-E1. J Biochem 97:97-104
7. 2 stimulates DNA synthesis by a cyclic AMP-independent pathway in osteoblastic clone MC3T3-E1. J Cell Physiol 128:155-161
8. Coleman RA, Smith WL, Narumia S (1994) Classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol Rev 46:205-229
9. 2 subtype. Mol Pharmacol 46:213-220
10. Kodama H, Amagi Y, Sodou H, Kasai S, Yamamoto S (1981) Establishment of a clonal osteogenic cell line from new-bone mouse calvaria. Jpn J Oral Biol 23:899-901
11. Suda M, Tanaka K, Natsui K, Usui T, Tanaka I, Fukushima M, Shigeno C, Konishi J, Narumiya S, Ichikawa A, Nakao K (1996) Prostaglandin E receptor subtypes in mouse osteoblastic cell line. Endocrinology 137:1698-1705
12. Stein GS, Lian JB, Stein JL, von Wijnen AJ, Frenkel B, Montecino M (1996) Mechanisms regulating osteoblast proliferation and differentiation. In: Bilezikian JP, Raisz LG, Rodan GA (eds) Principles of bone biology. Academic Press, San Diego, pp 69-86
13. Wang ZQ, Ovitt C, Grigoriadis AE, Möhle-Steinlein U, Rüther U, Wagner EF (1992) Bone and haematopoietic defects in mice lacking c-fos. Nature 360:741-745
14. Wang ZQ, Grigoriadis AE, Möhle-Steinlein U, Wagner EF (1991) A novel target cell for c-fos-induced oncogenesis: development of chondrogenic tumours in embryonic stem cell chimeras. EMBO J 10:2437-2450
15. 2): a potential mediator of c-fos expression induced by hydrostatic pressure in osteoblastic cells. Eur J Clin Invest 26:544-548
16. 2 induces early-response genes in rat bones. Bone 20:347-353
17. 2 in young rats increases the osteogenic capacity of bone marrow. Bone 20: 521-526
18. Morgan JI, Cohen DR, Hempstead JL, Curran T (1987) Mapping patterns of c-fos expression in the central nervous system after seizure. Science 237:192-197
19. Hanazawa S, Takeshita A, Amano S, Semba T, Nirazuka T, Katoh H, Kitano S (1993) Tumor necrosis factor-α induces expression of monocyte chemoattractant JE via fos and jun gene in clonal osteoblastic MC3T3-E1 Cells. J Biol Chem 268:9526-9532
20. 1 subtype of PGE receptor in mouse MC3T3-E1 cells. Calcif Tissue Int 62:327-331
21. Triffitt JT (1996) The stem cell of the osteoblast. In: Bilezikian JP, Raisz LG, Rodan GA (eds) Principles of bone biology. Academic Press, San Diego, pp 39-50
22. McCabe LR, Kockx M, Lian J, Stein J, Stein G (1995) Selective expression of fos-and jun-related genes during osteoblast proliferation and differentiation. Exp Cell Res 218:255-262
23. Lian JB, Stein GS, Bortell R, Owen TA (1991) Phenotype suppression: a postulated molecular mechanism for mediating the relationship of proliferation and differentiation by fos/jun interactions at AP-1 sites in steroid-responsive promoter elements of tissue-specific genes. J Cell Biochem 45:9-14
24. Owen TA, Aronow M, Shalhoub V, Barone LM, Wilming L, Tassinari MS, Kennedy MB, Pockwinseb S, Lian JB, Stein GS (1990) Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation during formation of the bone extracellular matrix. J Cell Physiol 143:420-430
25. Owen TA, Bortell R, Yocum SA, Smock SL, Zhang M, Abate C, Shalhoub V, Aronin N, Wright KL, van Wijnen AJ, Stein JL, Curran T, Lian JB, Stein GS (1990) Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription. Proc Natl Acad Sci USA 87:9990-9994
26. Schüle R, Umesono K, Mangelsdorf DJ, Bolado J, Pike JW, Evans RM (1990) Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene. Cell 61:497-504
27. 2 induces Egr-1 mRNA in MC3T3-E1 osteoblastic cells by a protein kinase C-dependent pathway. Prostaglandins Leukot Essen Fatty Acids 54:109-114
28. Machwate M, Jullienne A, Moukhtar M, Lomri A, Marie PJ (1995) c-fos protooncogene is involved in the mitogenic effect of transforming growth factor-β in osteoblastic cells. Mol Endocrinol 9:187-198