Synthesis and conformational analysis of some new pyrano[2, 3-c]xanthen-7-one and pyrano[3, 2-a]xanthen-6one derivatives with cytotoxic activity

Heterocycles

Volumn 53, Issue 1, 2000, Pages 93-106

  Ghirtis, Konstantinos ^a,e   Pouli, Nicole ^b   Marakos, Panagiotis ^c   Skaltsounis, Alexios Leandros ^d   Léonce, Stéphane ^a   Caignard, Daniel H ^a   Atassi, Ghanem ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b Division of Pharmacognosy

^c Panepistimiopolis Zografou   (Greece)

^d INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^e NONE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACRONINE; ANTINEOPLASTIC AGENT; PYRANO[2,3 C]XANTHEN 7 ONE; PYRANO[3,2 B]XANTHEN 6 ONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; MURINE LEUKEMIA; NONHUMAN; STRUCTURE ANALYSIS;

EID: 0033966064     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-99-8727     Document Type: Article

References (18)

1. G.M. Kitanov and K. F. Blinova, Chem. Nat. Compas, 1987, 2, 151.
2. K. Hostettman and H. Wagner, Phytochemistry, 1977, 16, 821.
3. A. Banerji, A. D. Deshpande, B. R. Prabhu, and P. Pradhan, J. Nat. Prod, 1994, 57, 396.
4. H. Tosa, M. linuma, T. Tanaka, H. Nosaki, S. Ikeda, K. Tsutsui, M. Yamada, and S. Fujimori, Chem. Pharm. Bull., 1997, 45, 418.
5. a) G.W. Rewcastle, G. J. Atwell, B. C. Baguley, S. B. Calveley, and W. A. Denny, J. Med. Chem., 1989, 32, 793.
6. b) G.J. Atwell, G. W. Rewcastle, B. C. Baguley, and W. A. Denny, J. Med. Chem., 1990, 33, 1345.
7. a) A.M. Habib, D. K. Ho, S. Masuda, T. McCloud, K. S. Reddy, M. Abu-Shoer, A. McKenzie, S. R. Byrn, C. J. Chang, and J. M. Cassady, J. Org. Chem., 1987, 52, 412.
8. b) D.K. Ho, A. T. McKenzie, S. R. Byrn, and J. M. Cassady, J. Org. Chem., 1987, 52, 342.
9. G.H. Svoboda, G. A. Poore, P. J. Simpson, and G. B. Boder, J. Pharm. Sei., 1966, 55, 758.
10. R.T. Dorr, J. D. Liddil, D. D. Von Hoff, M. Soble, and C. K. Osborne, Cancer Res., 1989, 49, 340.
11. A. Elomri, S. Mitaku, S. Michel, A. L. Skaltsounis, F. Tillequin, M. Koch, A. Pierre, N. Guilbaud, S. Léonce, L. Kraus-Berthier, Y. Rolland, and G. Atassi, J. Med. Chem., 1996, 39, 4762.
12. R.K.M. Pillai, P. Naiksatam, F. Johnson, R. Rajagopalan, P. C. Watts, R. Cricchio, and S. Boiras, J. Org. Chem., 1986, 51, 717.
13. a) D. Bell, M. R. Davies, G. R. Geen, and I. S. Mann, Synthesis, 1995, 707. b) J. D. Godfrey Jr, R. H. Mueller, T. C. Sedegran, N. Soundarajan, and V. J. Colandrea, Tetrahedron Lett., 1994, 35, 6405.
14. J. Schneider, E. L. Evans, E. Grunberg, and R. lan Fryer, J. Med. Chem., 1972, 15, 266.
15. E. Mikros, Mitaku, A. L Skaltsounis, F. Libot, F. Tillequin, and M. Koch, Magn. Reson. Chem., 1999, 37, 498.
16. V.K. Ahluwalia, R. S. Jolly, and A. K. Tehim, J. Chem. Soc., Perkin Trans.I, 1983, 1229.
17. O.R. Gottlieb, M. T. Magalhaes, M. O. da Suva Pereira, A. A. L. Mesquita, D. de Barros Correa, and G. G. de Oliveira, Tetrahedron, 1968, 24, 1601.
18. a) S. Léonce, A. Pierre, M. Anstett, V. Perez, A. Genton, J.-P. Bizzari, and G. Atassi, Biochem. Pharmacol, 1992, 44, 1707. b) A. Pierre, T. A. Dünn, L. Kraus-Berthier, S. Léonce, D. Saint-Dizier, G. Régnier, A. Dhainaut, M. Berlion, J.-P. Bizzari, and G. Atassi, Investigational New Drugs, 1992, 10, 137.