Effects of a new triazinoaminopiperidine derivative on adriamycin accumulation and retention in cells displaying P-glycoprotein-mediated multidrug resistance

Biochemical Pharmacology

Volumn 44, Issue 9, 1992, Pages 1707-1715

  Léonce, Stéphane ^a,b   Pierré, Alain ^a,b   Anstett, Monique ^a,b   Pérez, Valérie ^a,b   Genton, Annie ^a,b   Bizzari, Jean Pierre ^a,b   Atassi, Ghanem ^a,b  

^a INSTITUT DE RECHERCHES SERVIER   (France)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 BIS(ALLYLAMINO) 6 [4 [[2,2 BIS(4 FLUOROPHENYL)ETHYL]AMINO]PIPERIDINO] 1,3,5 TRIAZINE; AZIDOPINE; DACTINOMYCIN; DOXORUBICIN; GLYCOPROTEIN P; PIPERIDINE DERIVATIVE; RADIOISOTOPE; VERAPAMIL;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL CYCLE; CELL LINE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CONCENTRATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA P 388; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL;

ADENOCARCINOMA; ANIMAL; ANTINEOPLASTIC AGENTS; AZIDES; CARCINOMA, SQUAMOUS CELL; CELL CYCLE; CELL MEMBRANE; CELLS, CULTURED; COLONIC NEOPLASMS; COMPARATIVE STUDY; CRICETULUS; DIHYDROPYRIDINES; DOXORUBICIN; DRUG RESISTANCE; FLOW CYTOMETRY; FLUORESCENCE; HAMSTERS; HUMAN; KINETICS; LEUKEMIA P388; LEUKEMIA, MYELOCYTIC, ACUTE; LUNG; MEMBRANE GLYCOPROTEINS; MICE; P-GLYCOPROTEIN; PIPERIDINES; SENSITIVITY AND SPECIFICITY; TRIAZINES; TRITIUM; TUMOR CELLS, CULTURED; VERAPAMIL;

EID: 0026457778     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(92)90063-O     Document Type: Article

References (26)

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