Neurochemistry of mammalian entrainment: Signal transduction pathways in the suprachiasmatic nuclei

Biological Rhythm Research

Volumn 31, Issue 1, 2000, Pages 56-70

  Golombek, Diego A ^a   Ferreyra, Gabriela A ^b   Katz, Marcelo E ^b   Marpegan, Luciano ^b   Pinto, Felicitas De Tezanos ^b   Alfonso, Tomás Fernández ^b   Yannielli, Paola C ^b  

^a UNIVERSIDAD NACIONAL DE QUILMES   (Argentina)

^b NONE

Author keywords

Circadian rhythms; Entrainment; Glutamate; Protein kinase; Signal transduction; Suprachiasmatic nuclei

Indexed keywords

PHOSPHATASE; PROTEIN KINASE (CALCIUM,CALMODULIN);

ARTICLE; CALCIUM CELL LEVEL; CIRCADIAN RHYTHM; ENZYME ACTIVATION; NEUROCHEMISTRY; NONHUMAN; SIGNAL TRANSDUCTION; SUPRACHIASMATIC NUCLEUS;

MAMMALIA;

EID: 0033963947     PISSN: 09291016     EISSN: None     Source Type: Journal    
DOI: 10.1076/0929-1016(200002)31:1;1-0;FT056     Document Type: Article

References (100)

1. Abe H, Rusak B, Robertson HA (1991): Photic induction of Fos protein in the suprachiasmatic nucleus is inhibited by the NMDA receptor antagonist MK-801. Neurosci Lett 127: 9-12.
2. Abe H, Rusak B, Robertson HA (1992): NMDA and non-NMDA receptor antagonists inhibit photic induction of Fos protein in the hamster suprachiasmatic nucleus. Brain Res Bull 28: 831-835.
3. Abe H, Rusak B (1994): Physiological mechanisms regulating photic induction of Fos-like protein in hamster suprachiasmatic nucleus. Neurosci Biobehav Rev 18: 531-536.
4. Aguilar-Roblero R, Chavez JL, Díaz-Miñoz M (1996): Circadian modulation of intracellular Ca2+ release channel (ryanodine receptor) in the suprachiasmatic nuclei. Soc Res Biol Rhythms 5: 73.
5. Alberi S, Dubois-Dauphin M, Dreifuss JJ, Raggenbass M (1997): Whole-cell NMDA-evoked current in suprachiasmatic neurones of the rat: Modulation by extracellular calcium ions. Brain Res 745: 55-66.
6. Amir S, Robinson B, Edelstein K (1995): Distribution of NADPH-diaphorase staining and light-induced Fos expression in the rat suprachiasmatic nucleus region supports a role for nitric oxide in the circadian system. Neuroscience 69: 545-55.
7. Aronin N, Sagar SM, Sharp FR, Schwartz WJ (1990): Light regulates expression of a Fos-related protein in rat suprachiasmatic nuclei. Proc Nat Acad Sci USA 87: 5959-5962.
8. Bina KG, Cornell-Bell AQH, van den Pol AN (1993): Metabotropic glutamate receptors regulate calcium from cultured neurons and glia from the suprachiasmatic nucleus. Soc Neurosci Abst 19: 1815.
9. Bredt DS, Snyder SH (1989): Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci USA 86: 9030-903.
10. Cagampang FR, Rattray M, Powell JF, Chong NW, Campbell IC, Coen CW (1996): Circadian variation of EAAC1 glutamate transporter messenger RNA in the rat suprachiasmatic nuclei. Mol Brain Res 35: 190-196.
11. Castel M, Belenky M, Cohen S, Ottersen OP, Storm-Mathisen J (1993): Glutamate-like immunoreactivity in retinal terminals of the mouse suprachiasmatic nucleus. Eur J Neurosci 5: 368-381.
12. Chambille I, Doyle S, Serviere J (1993): Photic-induction and circadian expression of Fos-like protein. Immunohistochemical study in the retina and suprachiasmatic nuclei of hamster. Brain Res 612: 138-150.
13. Colwell CS, Menaker M (1992): NMDA as well as non-NMDA receptor antagonists can prevent the phase shifting effects of light on the circadian system of the golden hamster. J Biol Rhythms 7: 125-136.
14. Daan S, Pittendrigh C (1976): A functional analysis of circadian pacemakers in nocturnal rodents. II. The variability of phase response curves. J comp Physiol 106: 253-266.
15. Darlington TK, Wager-Smith K, Ceriani MF, Staknis D, Gekakis N, Steeves TDL, Weitz CJ, Takahashi JS, Kay SA (1998): Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim. Science 280: 1599-1563.
16. De Vries MJ, Lakke EAJF (1995): Retrograde labeling of retinal ganglion cells and brain neuronal subsets by (3H)-D-aspartate injection in the Syrian hamster hypothalamus. Brain Res Bull 38: 349-354.
17. De Vries MJ, Meijer JH (1991): Aspartate injections into the suprachiasmatic region of the Syrian hamster do not mimic the effects of light on the circadian activity rhythm. Neurosci Lett 127: 215-218.
18. De Vries MJ, Nunez Cardozo B, Van der Want J, De Wolf A, Meijer JH (1993): Glutamate immuno-reactivity in terminals of the retinohypothalamic tract of the brown Norwegian rat. Brain Res 612: 231-237.
19. De Vries MJ, Treep JA, de Pauw ES, Meijer JH (1994): The effects of electrical stimulation of the optic nerves and anterior optic chiasm on the circadian rhythm of the Syrian hamster: Involvement of excitatory amino acids. Brain Res 642: 206-212.
20. DeCoursey P (1989). Photoentrainment of circadian rhythms: An ecologist's viewpoint. In: T. H. Hiroshige K (eds.) Circadian clocks and ecology. Hokkaido Univ Press, Sapporo, pp. 187-206.
21. Ding JM, Chen D, Weber ET, Faiman LE, Rea MA, Gilette MU (1994): Resetting the biological clock: Mediation of nocturnal circadian shifts by glutamate and NO. Science 266: 1713-1717.
22. Ding JM, Faiman LE, Hurst WJ, Kuriashka LR, Gillette MU (1997): Resetting the biological clock: Mediation of nocturnal CREB phosphorylation via light, glutamate, and nitric oxide. J Neurosci 17: 667-675.
23. Ding JM, Buchanan GF, Tischkau SA, Chen D, Kuriashkina L, Faiman LE, Alster JM, McPherson PS, Campbell KP, Gillette MU (1998): A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock. Nature 394: 381-384
24. Ebling FJP, Maywood ES, Staley K, Humby T, Hancock DC, Waters CM, Evan GI, Hastings MH (1991): The role of N-methyl-D-aspartate-type glutamergic neurotransmission in the photic induction of immediate-early gene expression in the suprachiasmatic nuclei of the Syrian hamster. J Neuroendocrinol 3: 640-652.
25. Ebling FJP (1996): The role of glutamate in the photic regulation of the suprachiasmatic nucleus. Prog Neurobiol 50: 109-132.
26. Ferreyra GA, Cammarota MP, Golombek DA (1998): Photic control of nitric oxide activity in the hamster suprachiamstaic nuclei. Brain Res 797: 190-196.
27. Ferreyra GA, Golombek DA (1998): cAMP-and cGMP-dependent protein kinase activity in the hamster suprachiasmatic nucleus. Soc Res Biol Rhythms, 6:
28. Foster RG, Provencio I, Hudson D, Fiske S, De Grip W, Menaker M (1991). Circadian photoreception in the retinally degenerate mouse (rd/rd). J Comp Physiol [A] 169: 39-50
29. Fukushima T, Shimazoe T, Shibata S, Watanabe A, Ono M, Hamada T, Watanabe S (1997): The involvement of calmodulin and Ca2+/calmodulin-dependent protein kinase II in the circadian rhythms controlled by the suprachiasmatic nucleus. Neurosci Lett 227: 45-48.
30. Gannon RL, Rea MA (1993): Glutamate receptor immunoreactivity in the rat suprachiasmatic nucleus. Brain Res 622: 337-342.
31. Gannon RL, Rea MA (1994): In situ hybridization of antisense mRNA oligonucleotides for AMPA, NMDA and metabotropic glutamate receptor subtypes in the rat suprachiasmatic nucleus at different phases of the circadian cycle. Molec Brain Res 23: 338-344.
32. Gekakis N, Staknis D, Hguyen HB, Davis FC, Wilshacher LD, King DP, Takahashi JS, Weitz CJ (1998): Role of the CLOCK protein in the mammalian circadian mechanism. Science 280: 1564-1569.
33. Ghosh A, Greenberg ME (1995): Calcium signaling in neurons: Molecular mechanisms and cellular consequences. Science 268: 239-247.
34. Gillette MU, Medanic M, McArthur AJ, Liu C, Ding JM, Faiman LE, Weber ET, Tcheng TK, Gallman EA (1995): Electrophysiology of the SCN clock: Intrinsic neuronal rhythms and their adjustment. In: J Waterhouse (eds.) Circadian rhythms and their adjustment. Ciba Foundation Symposium, Wiley, Chichester, pp. 134-153.
35. Gillette MU (1996): Regulation of entrainment pathways by the suprachiasmatic circadian clock: Sensitivities to second messengers. Prog Brain Res 111: 121-132.
36. 2+ influx requires cAMP-dependent protein kinase in PC12 cells. J Biol Chem 266: 17454-17458.
37. Ginty DD, Kornhauser JM, Thompson MA, Bading H, Mayo KE, Takahashi JS, Greenberg ME (1993): Regulation of CREB phosporylation in the suprachiasmatic nucleus by light and a circadian clock. Science 260: 238-241.
38. Golombek DA, Katz M, Ralph MR (1998): Calcineurin regulation of circadian rhythms and circadian responses to light. In Y Touitou (ed.) Biological clocks. Mechanisms and applications. Elsevier Science, Amsterdam, pp. 221-224.
39. Golombek DA, Ralph MR (1995): Circadian responses to light: The calmodulin connection. Neurosci Lett 192: 101-104.
40. Golombek DA, Ralph MR (1994): KN-62, an inhibitor of Ca2+/calmodulin kinase II, attenuates circadian responses to light. Neuroreport 5: 1638-1640.
41. Golombek DA, Ralph MR (1996): Let there be light: Signal transduction in a mammalian circadian system. Braz J Med Biol Res 29: 131-140.
42. Hartgraves MD, Fuchs JL (1994): NMDA receptor binding in rodent suprachiasmatic nucleus. Brain Res 640: 113-118.
43. Hastings MH, Best JD, Ebling FJP, Maywood ES, McNulty S, Schurov I, Selvage D, Sloper P, Smith K (1996): Entrainment of the circadian clock. Prog Brain Res 111: 147-174.
44. Hastings MH (1995): Circadian Rhythms: Peering into the molecular clock. J Neuroendocrinol 7: 331-340.
45. Honrado GI, Johnson RS, Golombek DA, Spiegelman BM, Papaiannou VE, Ralph MR (1996): The circadian system of c-fos deficient mice. J Comp Physiol 178: 563-570.
46. Inouye S, Takahashi J, Wollnik F, Turek F (1988): Inhibitor of protein synthesis phase shifts a circadian pacemaker in mammalian SCN. Am J Physiol 255: R1055-R1058.
47. Ishida N, Matsui M, Mitsui Y, Mishina M (1994): Circadian expression of NMDA receptor mRNAs, e3 and x1 in the suprachiasmatic nucleus of rat brain. Neurosci Lett 166: 211-215.
48. Kafka MS, Benedito MA, Steele LK, Gibson MJ, Zerbe RL, Jacobwitz DM, Roth RH, Zander K (1986): Relationship between behavioral rhythms, plasma corticosterone and hypothalamic circadian rhythms. Chronobiol Int 3: 117-122.
49. Kako K, Wakamatsu H, Ishida N (1996): c-fos CRE-binding activity of CREB/ATF family in the SCN is regulated by light but not a circadian clock Neurosci Lett 216: 1259-1262.
50. Klein DC, Moore RY, Reppert SM (1991): Suprachiasmatic nucleus: The mind's clock. Oxford University Press, New York.
51. Kornhauser J, Nelson D, Mayo K, Takahashi JS (1990): Photic and circadian regulation of c-fos gene expression in the hamster suprachiasmatic nucleus. Neuron 5: 127-134.
52. Kornhauser JM, Ginty DD, Greenberg ME, Mayo KE, Takahashi JS (1996): Light entrainment and activation of signal transduction pathways in the SCN. Prog Brain Res 111: 133-146.
53. Kornhauser JM, Mayo KE, Takahashi JS (1992): Immediate-early gene expression in a mammalian circadian pacemaker: The suprachiasmatic nucleus. In M. Young (ed.). Molecular genetics of circadian rhythms. Marcel Dekker, New York, pp. 271-307.
54. Kornhauser JM, Nelson DE, Mayo KE, Takahashi JS (1992): Regulation of jun-B messenger and AP-1 activity by light and a circadian clock. Science 255: 1581-1584.
55. Liou SY, Shibata S, Iwasaki K, Ueki S (1986): Optic nerve stimulation-induced increase of release of 3H-glutamate and 3H-aspartate but not 3H GABA from the suprachiasmatic nucleus in slices of rat hypothalamus. Brain Res Bull 16: 527-531.
56. Liu C, Gillete MU (1996): Cholinergic regulation of the suprachiasmatic nucleus circadian rhythm via a muscarinic mechanism at night. J Neurosci 16: 744-751.
57. Lucas RJ, Foster, RG (1999): Photoentrainment in mammals: a role for cryptochrome. J Biol Rhythms 14: 4-10.
58. Mathur A, Golombek DA, Ralph MR (1996): cGMP-dependent protein kinase inhibitors block light-induced phase advances of circadian rhythms in vivo. Am J. Physiol 270: R1031-R1036.
59. Meeker RB, Greenwood RS, Hayward JN (1994): Glutamate receptors in the rat hypothalamus and pituitary. Endocrinology 134: 621-629.
60. Meijer JH, van der Zee EA, Dietz M (1988): Glutamate phase shifts circadian activity rhythms in hamsters. Neurosci Lett 86: 177-183.
61. Meijer JH, Rietveld WJ (1989): Neurophysiology of the suprachiasmatic circadian pacemaker in rodents. Physiol Rev 671-707.
62. Melo L, Golombek DA, Ralph MR (1997): Regulation of circadian photic responses by nitric oxide, J Biol Rhythms 12: 319-326.
63. Mikkelsen JD, Larsen PJ, Mick G, Vrang N, Ebling FJP, Maywood ES, Hastings MH, Moller M (1995): Gating of retinal inputs through the suprachiasmatic nucleus: Role of excitatory neurotransmission. Neurochem Int 27: 263-272.
64. Mintz EM, Albers HE (1997): Microinjection of NMDA into the SCN region mimics the phase shifting effect of light in hamsters. Brain Res 758: 245-249.
65. Moffett JR, Williamson L, Palkovitz M, Namboodiri MAA (1990): N-acetylaspartylglutamate: a transmitter candidate for the retinohypothalamic tract. Proc Nat Acad Sci USA 87: 8065-8069.
66. Moore RY, Lenn NJ (1972): A retinohypothalamic projection in the rat. J Comp Neural 146: 1-14.
67. Moore RY (1996): Entrainment pathways and the functional organization of the circadian system. Prog Brain Res 111: 103-119.
68. Morin L (1994): The circadian visual system. Brain Res Rev 67: 102-127.
69. Nelson DE, Takahashi JS (1991): Sensitivity and integration in a visual pathway for circadian entrainment in the hamster (Mesocricetus auratus). J Physiol 439: 115-145.
70. Obrietan K, Impey S, Storm DR (1998): Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei. Nature Neuroscience 8: 693-700.
71. Pickard GE (1982): The afferent conncetions of the suprachiasmatic nucleus of the golden hamster with emphasis on the retinohypothalamic projection. J Comp Neurol 211: 5-83.
72. Pittendrigh C S (1981): Circadian systems: Entrainment. In J Aschoff (ed.) Handbook of Behavioral Neurobiology: Biological rhythms. Plenum, New York, pp. 95-124.
73. Pittendrigh C (1965): On the mechanism of the entrainment of a circadian rhythm by light cycles. In: J Aschoff (ed.) Circadian Clocks. North Holland Pub Co, Amsterdam, pp. 277-297.
74. Prosser R A, McArthur A, Gillette MU (1989): cGMP induces phase shifts of a mammalian circadian pacemaker at night, in antiphase to cAMP effects. Proc Nat Acad Sci (USA) 86: 6812-6815.
75. Prosser R, Heller H, Miller J (1994): Serotonergic phase advances of the mammalian circadian clock involve protein kinase A and K channel opening. Brain Res 664: 67-73.
76. Prosser RA, Gillette MU (1989): The mammalian circadian clock in the suprachiasmatic nuclei is reset in vitro by cAMP. J Neurosci 9: 1073-1081.
77. Rea M, Buckely B, Lutton L (1993): Local administration of EAA antagonists blocks light-induced phase shifts and c-fos expression in hamster SCN. Am J Physiol 265: R1191-R1198.
78. Rea MA (1989): Light induces Fos-related protein immunoreactivity in the rat suprachiasmatic nuclei. Brain Res Bull 23: 577-581.
79. Reuss S, Decker K, Röbeler L, Layes E, Schollmayer A, Spessert R (1995): Nitric oxide synthase in the hypothalamic nucleus of rat: evidence from histochemistry, immunohistochemistry and Western blot; and colocalization with VIP. Brain Res 695: 257-262.
80. Rodriguez-Alvarez J, Lafon-Cazal M, Bockaert J (1996). The CaM-kinase II inhibitor KN-62 blocks NMDA but not kainate stimulation of NO synthesis. Neuroreport 7: 2525-2528.
81. Rusak B, McNaughton L, Robertson HA, Hunt SP (1992): Circadian variation in photic regulation of immediate-early gene mRNAs in rat suprachiasmatic nucleus cells. Molec Brain Res 14: 124-130.
82. Rusak B, Robertson H, Wisden W, Hunt SP (1990): Light pulses that shift rhythms induce gene expression in the suprachiasmatic nucleus. Science 248: 1237-1240.
83. Schwaninger M, Blume R, Oetjen E, Lux G, Knepel W (1993): Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization. J Biol Chem 268: 23111-23115.
84. Schwartz WJ, Aronin N, Takeuchi J, Bennett MR, Peters RV (1995): Towards a molecular biology of the suprachiasmatic nucleus: photic and temporal regulation of c-fos gene expression. Sem Neurosci 7: 53-60.
85. Schwartz WJ, Aronin N (1992): Expression of AP-1 transcriptional regulatory proteins in the rat suprachiasmatic nucelus. Disc Neurosci 8: 44-48.
86. Shibata S, Watanabe A, Hamada T, Ono M, Watanabe S (1994): N-methyl-D-aspartate induces phase shifts in circadian rhythm of neuronal activity of rat SCN in vitro. Am J Physiol 267: R360-R364.
87. Stamp JA, Piggins HD, Rusak B, Semba K (1997): Distribution of ionotropic glutamate receptor subunit immunoreactivity in the suprachiasmatic nucleus and intergeniculate leaflet of the hamster. Brain Res 756: 215-224.
88. Takahashi J, DeCoursey PJ, Bauman L, Menaker M (1984): Spectral sensitivity of a novel photoreceptive system medianting entrainment of mammalian circadian rhythms. Nature 308: 186-188.
89. Takeuchi J, Shannon W, Aronin N, Schwartz WJ (1993): Compositional changes of AP-1 binding proteins are regulated by light in a mammalian circadian clock. Neuron 11: 825-836.
90. Tanaka M, Amaya F, Tamada Y, Okamura H, Hisa Y, Ibata Y (1997): Induction of NGFI-A gene expression in the rat suprachiasmatic nucleus by photic stimulation. Brain Res 756: 305-310.
91. Tei H, Okamura H, Shigeyoshi Y, Fukuhara C, Ozawa R, Hirose M, Sakaki Y (1997): Circadian oscillation of a mammalian homologue of the Drosophila period gene. Nature 389: 512-516
92. Van den Pol AM, Finkbeiner SM, Cornell-Bell AH (1992): Calcium excitability and oscillations in suprachiasmatic nucleus neurons and glia in vitro. J Neurosci 12: 2648-2664.
93. Van den Pol AN, Cao V, Belousov AB (1996): Dopamine enhancement and depression of glutamate-regulated calcium and electrical activity in hypothalamic neurons. J Neurophysiol 76: 3934-3948.
94. Wang X, Robinson P (1995): Cyclic GMP-dependent protein kinase substrates in rat brain. J Neurochem 65:595-604.
95. Watanabe A, Hamada T, Shibata S, Watanabe S (1994): Effects of nitric oxide synthase inhibitors on N-methyl-D-aspartate-induced phase delay of circadian rhythm of neuronal activity in vitro. Brain Res 646: 161-164.
96. Watanabe A, Ono M, Shibata S, Watanabe S (1995): Effect of a nitric oxide synthase inhibitor, N-nitro-L-arginne methyl ester, on light-induced phase delay of circadian wheel-running activity in golden hamsters. Neurosci Lett 192: 25-28.
97. Weber ET, Gannon RT, Michel AM, Gillette MU, Rea MA (1995): Nitric oxide inhibitor blocks light-induced phase shifts of the circadian rhythm, but not c-fos expression in the suprachiasmatic nucleus of the Syrian hamster. Brain Res 692: 137-142.
98. Weber T, Gillette MU (1990): Endogenous circadian changes in cGMP levels in the rat suprachiasmatic nucleus. Soc Neurosci Abst 16: 317-8.
99. Westphal RS, Anderson KA, Means AR, Wadzinski BE (1998): A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A. Science 280: 1258-1261.
100. Wollnik F, Brysch W, Uhlmann E, Gillardon F, Bravo R, Zimmermann M, Schlingensiepen KH, Herdegen T (1995): Block of c-Fos and JunB expression by antisense oligonucleotides inhibits light-induced phase shifts of the mammalian circadian clock. Eur J Neurosci 7: 388-393.