Membrane fluidity changes are associated with the antiarrhythmic effects of docosahexaenoic acid in adult rat cardiomyocytes

Journal of Nutritional Biochemistry

Volumn 11, Issue 1, 2000, Pages 38-44

  Leifert, Wayne R ^a,b   Jahangiri, Anisa ^a,b   McMurchie, Edward J ^b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b CSIRO   (Australia)

Author keywords

Arrhythmia; Cardiomyocytes; Docosahexaenoic acid; Polyunsaturated fatty acids

Indexed keywords

BENZYL ALCOHOL; DOCOSAHEXAENOIC ACID; FLUORESCENT DYE; ISOPRENALINE; LYSOPHOSPHATIDYLCHOLINE; POLYUNSATURATED FATTY ACID;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FLUORESCENCE; HEART ARRHYTHMIA; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; IN VITRO STUDY; MALE; MEMBRANE FLUIDITY; NONHUMAN; RAT;

EID: 0033962277     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-2863(99)00069-8     Document Type: Article

References (32)

1. Siscovick D.S., Raghunathan T.E., King I., Weinmann S., Wicklund K.G., Albright J., Bovbjerg V., Arbogast P., Smith H., Kushi L.H., Cobb L.A., Copass M.K., Psaty B.M., Lemaitre R., Retzlaff B., Childs M., Knopp R.H. Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest. JAMA. 274:1995;1363-1367.
2. Kromhout D., Bosschieter E.B., de Lezenne Coulander C. The inverse relation between fish consumption and 20-year mortality from coronary heart disease. New Engl. J. Med. 312:1985;1205-1209.
3. Burr M.L., Fehily A.M., Gilbert J.F., Rogers S., Holliday R.M., Sweetnam P.M., Elwood P.C., Deadman N.M. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction Diet and reinfarction trial (DART) . Lancet. 334:1989;757-761.
4. Abeywardena M.Y., Charnock J.S. Dietary lipid modification of myocardial eicosanoids following ischemia and reperfusion in the rat. Lipids. 30:1995;1151-1156.
5. McLennan P.L., Abeywardena M.Y., Charnock J.S. Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion. Am. Heart. J. 116:1988;709-717.
6. McLennan P.L., Bridle T.M., Abeywardena M.Y., Charnock J.S. Comparative efficacy of n-3 and n-6 polyunsaturated fatty acids in modulating ventricular fibrillation threshold in marmoset monkeys. Am. J. Clin. Nutr. 58:1993;666-669.
7. Pepe S., McLennan P.L. Dietary fish oil confers direct antiarrhythmic properties on the myocardium of rats. J. Nutr. 126:1996;34-42.
8. Leaf A., Kang J.X. Prevention of cardiac sudden death by N-3 fatty acids A review of the evidence . J. Intern. Med. 240:1996;5-12.
9. Kang J.X., Leaf A. Protective effects of free polyunsaturated fatty acids on arrhythmias induced by lysophosphatidylcholine or palmitoylcarnitine in neonatal rat cardiac myocytes. Eur. J. Pharmacol. 297:1996;97-106.
10. Weylandt K.H., Kang J.X., Leaf A. Polyunsaturated fatty acids exert antiarrhythmic actions as free acids rather than in phospholipids. Lipids. 31:1996;977-982.
11. Kang J.X., Leaf A. Prevention and termination of beta-adrenergic agonist-induced arrhythmias by free polyunsaturated fatty acids in neonatal rat cardiac myocytes. Biochem. Biophys. Res. Commun. 208:1995;629-636.
12. McMurchie E.J., Leifert W.R., Head R.J. Antiarrhythmic properties of n-3 fatty acids in cardiomyocytes A role for membrane fluidity? Riemersma R.A., Armstrong R.A., Kelly R.W., Wilson R. Essential Fatty Acids and Eicosanoids. 1999;284-289 AOCS Press, Champaign, IL, USA.
13. Leifert W.R., McMurchie E.J., Head R.J. Prevention of asynchronous beating in adult rat cardiomyocytes by acute addition of n-3 polyunsaturated fatty acids. J. Mol. Cell. Cardiol. 29:1997;A323.
14. Leifert W.R., Jahangiri A., McMurchie E.J. Antiarrhythmic fatty acids and antioxidants in animal and cell studies. J. Nutr. Biochem. 10:1999;252-267.
15. de Jonge H.W., Dekkers D.H., Bastiaanse E.M., Bezstarosti K., van der Laarse A., Lamers J.M. Eicosapentaenoic acid incorporation in membrane phospholipids modulates receptor-mediated phospholipase C and membrane fluidity in rat ventricular myocytes in culture. J. Mol. Cell. Cardiol. 28:1996;1097-1108.
16. Lentz B.R. Membrane "fluidity" as detected by diphenylhexatriene probes. Chem. Phys. Lipids. 50:1989;171-190.
17. Kang J.X., Leaf A. Effects of long-chain polyunsaturated fatty acids on the contraction of neonatal rat cardiac myocytes. Proc. Natl. Acad. Sci. USA. 91:1994;9886-9890.
18. Kang J.X., Leaf A. Antiarrhythmic effects of polyunsaturated fatty acids. Recent studies. Circulation. 94:1996;1774-1780.
19. Bogdanov K.Y., Spurgeon H.A., Vinogradova T.M., Lakatta E.G. Modulation of the transient outward current in adult rat ventricular myocytes by polyunsaturated fatty acids. Am. J. Physiol. 274:1998;H571-H579.
20. Klitzner T.S. Maturational changes in excitation-contraction coupling in mammalian myocardium. J. Am. Coll. Cardiol. 17:1991;218-225.
21. Wetzel G.T., Klitzner T.S. Developmental cardiac electrophysiology recent advances in cellular physiology. Cardiovasc. Res. 31:1996;E52-E60.
22. Katz A.M. Ionic and pharmacological actions on cardiac rate and rhythm. Goodhart P.J., Goodhart H.L. Physiology of the Heart. 1977;229-256 Raven Press, New York, NY, USA.
23. De Ferrari G.M., Viola M.C., D'Amato E., Antolini R., Forti S. Distinct patterns of calcium transients during early and delayed afterdepolarizations induced by isoproterenol in ventricular myocytes. Circulation. 91:1995;2510-2515.
24. Sedlis S.P., Hom M., Sequeira J.M., Tritel M., Gindea A., Ladenson J.H., Jaffe A.S., Esposito R. Time course of lysophosphatidylcholine release from ischemic human myocardium parallels the time course of early ischemic ventricular arrhythmia. Coron. Artery Dis. 8:1997;19-27.
25. Liu S.Y., Yu C.H., Hays J.A., Panagia V., Dhalla N.S. Modification of heart sarcolemmal phosphoinositide pathway by lysophosphatidylcholine. Biochim. Biophys. Acta. 1349:1997;264-274.
26. Chen M., Hashizume H., Abiko Y. Effects of beta-adrenoceptor antagonists on Ca(2+)-overload induced by lysophosphatidylcholine in rat isolated cardiomyocytes. Br. J. Pharmacol. 118:1996;865-870.
27. Opie, L.H. (1998). Myocardial reperfusion: New ischaemic syndromes. In The Heart. Physiology, from Cell to Circulation. pp. 589-606, Lippincott-Raven, Philadelphia, PA, USA.
28. + channels of neonatal rat ventricular myocytes. Proc. Natl. Acad. Sci. USA. 92:1995;11000-11004.
29. 2+, and contraction in adult rat cardiac myocytes. Proc. Natl. Acad. Sci. USA. 91:1994;8832-8836.
30. McMurchie E.J. Dietary lipids and the regulation of membrane fluidity and function. Aloia R.C., Curtain C.C., Gordon L.M. Physiological Regulation of Membrane Fluidity. 1988;189-237 Alan R. Liss Inc, New York, NY, USA.
31. Nair S.S., Leitch J.W., Falconer J., Garg M.L. Prevention of cardiac arrhythmia by dietary (n-3) polyunsaturated fatty acids and their mechanism of action. J. Nutr. 127:1997;383-393.
32. de Lorgeril M., Renaud S., Mamelle N., Salen P., Martin J.L., Monjaud I., Guidollet J., Touboul P., Delaye J. Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet. 343:1994;1454-1459.