Effect of multiple serine/alanine mutations in the transmembrane spanning region V of the D2 dopamine receptor on ligand binding

Journal of Neurochemistry

Volumn 74, Issue 1, 2000, Pages 358-366

  Coley, Clare ^b   Woodward, Robert ^b   Johansson, Anette M ^a   Strange, Philip G ^b,c   Naylor, Louise H ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF KENT   (United Kingdom)

^c UNIVERSITY OF READING   (United Kingdom)

Author keywords

D2 dopamine receptor; Ligand binding; Mutagenesis; Serine residues

Indexed keywords

ALANINE; DOPAMINE; DOPAMINE 2 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; MUTANT PROTEIN; RECEPTOR PROTEIN; REMOXIPRIDE; SERINE; SPIPERONE; TETRALIN DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; DOPAMINERGIC SYSTEM; DRUG RECEPTOR BINDING; HYDROGEN BOND; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; RAT;

ALANINE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING, COMPETITIVE; COS CELLS; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; LIGANDS; MUTATION; RECEPTORS, DOPAMINE D2; SERINE;

ANIMALIA; TOBACCO MOSAIC VIRUS;

EID: 0033961819     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0740358.x     Document Type: Article

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