NGF treatment potentiates c-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid

Brain Research

Volumn 853, Issue 1, 2000, Pages 136-141

  Giovannelli, Lisa ^a   Veltri, Maria ^a   Casamenti, Fiorella ^a   Pepeu, Giancarlo ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cholinergic forebrain system; Early gene; Neurotrophin

Indexed keywords

CHOLINE ACETYLTRANSFERASE; EXCITOTOXIN; NERVE GROWTH FACTOR; PROTEIN C FOS; QUISQUALIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; CHOLINERGIC SYSTEM; CONTROLLED STUDY; EARLY RESPONSE GENE; FOREBRAIN; GENE EXPRESSION; IMMUNOREACTIVITY; MALE; NEUROPROTECTION; NONHUMAN; OLIVARY NUCLEUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT;

ANIMALS; BASAL NUCLEUS OF MEYNERT; CEREBRAL CORTEX; CHOLINE O-ACETYLTRANSFERASE; DRUG SYNERGISM; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENTRICULAR; MALE; NERVE GROWTH FACTOR; NEURONS; PROTO-ONCOGENE PROTEINS C-FOS; QUISQUALIC ACID; RATS; RATS, WISTAR; THALAMUS;

EID: 0033961805     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02312-4     Document Type: Article

References (27)

1. Casamenti F., Scali C., Giovannelli L., Faussone-Pellegrini M.S., Pepeu G. Effect of nerve growth factor and GM1 ganglioside on the recovery of cholinergic neurons after a lesion of the nucleus basalis in aging rats. J. Neural Transm. 7:1994;177-193.
2. Connor B., Dragunow M. The role of neuronal growth factors in neurodegenerative disorders of the human brain. Brain Res. Rev. 27:1998;1-39.
3. Dekker A.J., Gage F.H., Thal L.J. Delayed treatment with nerve growth factor improves acquisition of a spatial task in rats with lesions of the nucleus basalis magnocellularis: evaluation of the involvement of different neurotransmitter systems. Neuroscience. 48:1992;111-119.
4. Dragunow M., Goulding M., Faull R.L.M., Ralph R., Mee E., Frith R. Induction of c-fos mRNA and protein in neurons and glia after traumatic brain injury: pharmacological characterization. Exp. Neurol. 107:1990;236-248.
5. Fischer W., Bjorklund A., Chen K., Gage F.H. NGF improves spatial memory in aged rodents as a function of age. J. Neurosci. 11:1991;1889-1906.
6. R.B. Gibbs, Estrogen and nerve-growth factor-related systems in brain: effects on basal forebrain cholinergic neurons and implications for learning and memory processes and aging, in: V.N. Luine, C.F. Harding (Eds.), Hormonal Restructuring of the Adult Brain: Basic and Clinical Perspectives, Vol. 743, New York Acad. Sci., NY, 1994, pp. 165-199.
7. NGFR and up-regulation by nerve growth factor. J. Comp. Neurol. 341:1994;324-339.
8. Gibbs R.B., Martynowski C. Nerve growth factor induces Fos-like immunoreactivity within identified cholinergic neurons in the adult rat basal forebrain. Brain Res. 753:1997;141-151.
9. Giovannelli L., Casamenti F., Pepeu G. C-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid: a study in adult and aged animals. J. Neural Transm. 105:1998;935-948.
10. Hayashi M., Yamashita A., Shimizu K. Nerve growth factor in the primate central nervous system: regional distribution and ontogeny. Neuroscience. 36:1990;683-689.
11. Hengerer B., Lindholm D., Heumann R., Ruther U., Wagner E.F., Thoenen H. Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos. Proc. Natl. Acad. Sci. U.S.A. 87:1990;3899-3903.
12. Herrera D.G., Robertson H.A. Activation of c-fos in the brain. Prog. Neurobiol. 50:1996;83-107.
13. Jorgensen M.B., Deckert J., Wright D.C., Gehlert D.R. Delayed c-fos proto-oncogene expression in the rat hippocampus induced by transient global cerebral ischemia: an in situ hybridization study. Brain Res. 484:1989;393-398.
14. Korsching S., Auburger G., Heumann R., Scott J., Thoenen H. Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J. 4:1985;1389-1393.
15. Kruijer W., Schubert D., Verma I.M. Induction of the proto-oncogene c-fos by nerve growth factor. Proc. Natl. Acad. Sci. U.S.A. 82:1985;7330-7334.
16. Mufson E.J., Conner J.M., Varon S., Kordower J.H. Nerve growth factor-like immunoreactive profiles in the primate basal forebrain and hippocampal formation. J. Comp. Neurol. 341:1994;507-519.
17. Onodera H., Kogure K., Ono Y., Igarashi K., Kiyota Y., Nagaoka A. Proto-oncogene c-fos is transiently induced in the rat cerebral cortex after forebrain ischemia. Neurosci. Lett. 98:1989;101-104.
18. Page K.J., Saha A., Everitt B.J. Differential activation and survival of basal forebrain neurons following infusions of excitatory amino acids: studies with the immediate early gene c-fos. Exp. Brain Res. 93:1993;412-422.
19. G. Paxinos, G. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, New York.
20. Peng Z.C., Chen S., Fusco M., Vantini G., Bentivoglio M. Fos induction by nerve growth factor in the adult rat brain. Brain Res. 632:1993;57-67.
21. Roßner S., Perez-Polo J.R., Wiley R.G., Schliebs R., Bigl V. Differential expression of immediate early genes in distinct layers of rat cerebral cortex after selective immunolesion of the forebrain cholinergic system. J. Neurosci. Res. 38:1994;282-293.
22. Scali C., Casamenti F., Pazzagli M., Bartolini L., Pepeu G. Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition. Neurosci. Lett. 170:1994;117-120.
23. Schreiber S.S., Baudry M. Selective neuronal vulnerability in the hippocampus - a role for gene expression? Trends Neurosci. 18:1995;446-451.
24. Sharp F.R., Gonzales M.F., Hisanaga K., Mobley W.C., Sagar S.M. Induction of the c-fos gene product in rat forebrain following cortical lesions and NGF injections. Neurosci. Lett. 100:1989;117-122.
25. Tuszynski M.H., Sang U.H., Amaral D.G., Gage F.H. Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration. J. Neurosci. 10:1990;3604-3614.
26. Whittemore S.R., Sieger A. The expression, localization and functional significance of β-nerve growth factor messenger RNA and protein in the central nervous system. Brain Res. Rev. 12:1987;439-464.
27. Wilcox B.J., Applegate M.D., Portera-Cailliau C., Koliatsos V.E. Nerve growth factor prevents apoptotic cell death in injured central cholinergic neurons. J. Comp. Neurol. 359:1995;573-585.