Challenges of toxicology for the millennium

Therapeutic Drug Monitoring

Volumn 22, Issue 1, 2000, Pages 52-57

  Wong, Steven H Y ^a,b,c,d  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b DYNACARE LABORATORIES   (Canada)

^c Milwaukee County Medical Examiner's Office   (United States)

^d Wisconsin Correctional Services   (United States)

Author keywords

Chemical terrorism; Criminalistic toxicology; Domestic preparedness; Pharmacogenetics

Indexed keywords

ARTICLE; CHEMICAL WARFARE; FORENSIC PATHOLOGY; GENOTYPE; GOVERNMENT; HEALTH CARE QUALITY; PHARMACOGENETICS; PRIORITY JOURNAL; SAMPLING; TOXICOLOGY;

ANIMALS; BIOLOGICAL WARFARE; CHEMICAL WARFARE; FORENSIC MEDICINE; GENETICS; HUMANS; NUCLEAR WARFARE; TERRORISM; TOXICOLOGY;

EID: 0033961759     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-200002000-00011     Document Type: Article

References (24)

1. Chemical Casualty Care Office. Medical Management of Chemical Casualties - Handbook. 2nd ed. Aberdeen Proving Ground, MD: US Army Medical Research, Institute of Chemical Defense; 1995.
2. Operational Medicine Department. Medical Management of Biological Casualties - Handbook. 2nd ed. Fort Detrick, Frederick, MD: US Army Medical Research, Institute of Infectious Diseases; 1996.
3. Ember LR. Bioterrorism - combating the threat. Chem Eng News 1999;77:8-17.
4. Behonick GS. The forensic toxicological aspects of chemical terrorism - a workshop proposal. Society of Forensic Toxicologists Annual Meeting; October 2-6, 2000; Milwaukee, WI.
5. Proceeding from the national symposium on medical and public health response to bioterrorism (Washington, DC February 1999). Emerg Infect Dis 1999;5:491-565.
6. Center for Civilian Biodefense Studies. Johns Hopkins University. 1999. Available at: http://www.hopkins-biodefense.org.
7. Johnson G. Biological weapons threat should be taken seriously. Milwaukee Journal Sentinel. August 22, 1999:J1.
8. Office of the Sheriff - County of Milwaukee. Domestic preparedness measured response. Presented at: Milwaukee Biological Tabletop Exercise. Medical College of Wisconsin, August 20, 1999; Milwaukee, WI.
9. Frederick RS, Takafuji ET, Franz DR. Medical Aspects of Chemical and Biological Warfare. Part I. Textbook of Military Medicine. Washington, DC: Office of the Surgeon General, Borden Institute, Walter Reed Army Medical Center; 1997.
10. Cooper DL. What is Pharmacogenetics? Presented at: Pharmacogenetics in Patient Care. American Association for Clinical Chemistry; November, 6, 1998; Chicago, IL.
11. Weber WW. Pharmacogenetics. Oxford, UK: Oxford University Press, 1997:1-344.
12. Gonzalez FJ, Eichelbaum M, Yamazoe Y, eds. Pharmacogenetics. Philadelphia: Lippincott Williams & Wilkins, 1999;9.
13. Linder MW, Prough RA, Valdes R. Pharmacogenetics: a laboratory tool for optimizing therapeutic efficiency clinical chemistry. Clin Chem 1997;43:254-66.
14. Linder MW, Valdes R. Fundamentals and applications of pharmacogenetics for the clinical laboratory. Ann Clin Lab Sci 1999;29:140-9.
15. Linder MW, Nota F, Valdes RM, Looney S, Valdes Jr. An approach for design of pharmacogenetic (PG) screening-profiles and estimating impact on regional drug utilization. Clin Chem 1999;45S:A125.
16. Shen S, Chou W-H, Blouin RA, Wedlund PJ. The cyotchrome P450 2D6 (CYP2D6) enzyme polymorphism: screening costs and influence on clinical outcomes in psychiatry. Clin Pharmacol Ther 1996;60:522-34.
17. Bon MAM, Vermes I, Bergh van den FAJ, et al. Pharmacogenetics: a tool for TDM, a correlation study on CYP2D6 and nortriptyline. Clin Chem 1998;44S:A98.
18. Schur BC, Bjerke J, Nuwayhid N, Wong SHY, Harsch HH. Pharmacogenetics for rational drug therapy and understanding toxicity - genotyping CYP2D6 for antidepressants therapy. Annual Meeting of the Society of Forensic Toxicologists; October 1999; San Juan, Puerto Rico. Abstract.
19. Fjordside L, et al. The stereoselective metabolism of fluoxetine in poor and extensive metabolizers of sparteine. Pharmacogenetics 1999;9:55-60.
20. Walczak M, Williams T, Mohorko A, Sayner B, Fredericks D, Cannon RD, Wong SHY. Drugs of abuse testing in a Wisconsin corrections system facility. Clin Chem 1998;44:A92.
21. Wong SHY, Sunshine I, eds. Handbook of Analytical Therapeutic Drug Monitoring and Toxicology. Boca Raton, FL: CRC Press; 1997:354.
22. Bogusz MJ, Maier R-D, Kruger K-D, Kohls U. Determination of common drugs of abuse in body fluids using one isolation procedure and LC-APC-MS. The International Association of Forensic Toxicologists-Society of Forensic Toxicologists, Albuquerque, New Mexico, 1998. Abstract.
23. Limbach PA. Matrix-assisted laser desorption - ionization mass spectrometry: an overview. Spectrometry 1998;13:16-27.
24. Griffin TJ, Tang W, Smith LM. Genetic analysis by peptide nucleic acid affinity MALDI-TOF mass spectrometry. Nat Biotech 1997;15:1368-72.