Developmental change in GABA(A) receptor desensitization kinetics and its role in synapse function in rat cortical neurons

Journal of Physiology

Volumn 522, Issue 1, 2000, Pages 3-17

  Hutcheon, Bruce ^a   Morley, Paul ^a   Poulter, Michael O ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 5,6,7,8 TETRAHYDRO 7 HYDROXY 2 METHYLBENZO[B]THIENO[2,3 B]PYRIDINE 3 CARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; UNCLASSIFIED DRUG; AMINOPYRIDINE DERIVATIVE; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; THIOPHENE DERIVATIVE; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; INFORMATION PROCESSING; KINETICS; MEMBRANE CURRENT; NERVE CELL CULTURE; NERVE GROWTH; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; RECEPTOR DOWN REGULATION; SYNAPTIC TRANSMISSION; ANIMAL; BRAIN CORTEX; CELL AGING; CELL CULTURE; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; METABOLISM; NERVE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT; SYNAPSE; ADULTHOOD; CELL MATURATION; DEGRADATION KINETICS; IN VITRO STUDY; NERVOUS SYSTEM DEVELOPMENT; POSTSYNAPTIC POTENTIAL;

AMINOPYRIDINES; ANIMALS; CELL AGING; CELLS, CULTURED; CEREBRAL CORTEX; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; EMBRYO; GABA MODULATORS; KINETICS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SYNAPSES; THIOPHENES;

EID: 0033958536     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2000.t01-5-00003.xm     Document Type: Article

References (46)

1. A, NMDA and AMPA receptors: a developmentally regulated 'menage a trois'. Trends in Neurosciences 20, 523-529.
2. 2+ via changes of their desensitization kinetics: an in situ patch-clamp and single-cell PCR study. Journal of Neuroscience 18, 2437-2448.
3. BROOKS, K. A., JIN, H., PRICE, M. & DICHTER, M. A. (1997). Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo. Journal of Neurochemistry 70, 1017-1028.
4. CAULI, B., AUDINAT, E., LAMBOLEZ, B., ANGULO, M. C., ROPERT, N., TSUZUKI, K., HESTRIN, S. & ROSSIER, J. (1997). Molecular and physiological diversity of cortical nonpyramidal cells. Journal of Neuroscience 17, 3894-3906.
5. A receptor channels. Journal of Neurophysiology 71, 1318-1335.
6. DIAMOND, J. S. & JAHR, C. E. (1997). Transporters buffer synaptically released glutamate on a submillisecond time scale. Journal of Neuroscience 17, 4672-4687.
7. A receptor desensitization: the role of the γ2 subunit and its physiological significance. Journal of Physiology 497, 145-159.
8. A-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits. Journal of Comparative Neurology 359, 154-194.
9. A receptors underlying inhibitory synaptic currents in neocortical pyramidal neurons. Journal of Neuroscience 17, 7220-7227.
10. A receptor gating kinetics on the α-subunit isoform: implications for structure-function relations and synaptic transmission. Journal of Physiology 489, 529-543.
11. 2+ transients. Nature 375, 784-787.
12. A receptor currents in mouse fibroblasts. Journal of Physiology 514, 27-45.
13. HÁJOS, N. & MODY, I. (1997). Synaptic communication among hippocampal interneurons: Properties of spontaneous IPSCs in morphologically identified cells. Journal of Neuroscience 17, 8427-8442.
14. HOLLRIGEL, G. S. & SOLTESZ, I. (1997). Slow kinetics of miniature IPSCs during early postnatal development in granule cells of the dentate gyrus. Journal of Neuroscience 17, 5119-5128.
15. HUTCHEON, B. & POULTER, M. O. (1997). Developmental switch in desensitization kinetics determines time course of GABA mediated synaptic transmission. Society for Neuroscience Abstracts 23, 102.
16. JONES, M. V. & WESTBROOK, G. L. (1995). Desensitized states prolong GABAA channel responses to brief agonist pulses. Neuron 15, 181-191.
17. JONES, M. V. & WESTBROOK, G. L. (1997). Shaping of IPSC's by endogenous calcineurin activity. Journal of Neuroscience 17, 7626-7633.
18. KAWAGUCHI, Y. (1995). Physiological subgroups of nonpyramidal cells with specific morphological characteristics in layer II/III of rat frontal cortex. Journal of Neuroscience 15, 2638-2655.
19. LAURIE, D. J., WISDEN, W. & SEEBURG, P. H. (1992). The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. Journal of Neuroscience 12, 4151-4172.
20. 2+ rise in pyramidal cells and interneurons from rat neonatal hippocampal slices. Journal of Physiology 487, 319-329.
21. LOTURCO, J. J., OWENS, D. F., HEATH, M. J. S., DAVIS, M. B. E. & KRIEGSTEIN, A. R. (1995). GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis. Neuron 15, 1287-1298.
22. A receptor subunit mRNAs in rat spinal cord and dorsal root ganglia. Journal of Comparative Neurology 338, 337-359.
23. MEADOWS, H. J., HARRIES, M. H., THOMPSON, M. & BENHAM, C. D. (1997). Effect of SB-205384 on the decay of GABA-activated chloride currents in granule cells cultured from rat cerebellum. British Journal of Pharmacology 121, 1334-1338.
24. MEADOWS, H. J., KUMAR, C. S., PRITCHETT, D. B., BLACKBURN, T. P. & BENHAM, C. D. (1998). SB-205384: a GABA(A) receptor modulator with novel mechanism of action that shows subunit selectivity. British Journal of Pharmacology 123, 1253-1259.
25. NUSSER, Z., CULL-CANDY, S. & FARRANT, M. (1997). Differences in synaptic GABA(A) receptor number underlie variation in GABA mini amplitude. Neuron 19, 697-709.
26. NUSSER, Z., SIEGHART, W., BENKE, D., FRITSCHY, J. M. & SOMOGYI, P. (1996). Differential synaptic localization of two major γ-aminobutyric acid type A receptor α subunits on hippocampal pyramidal cells. Proceedings of the National Academy of Sciences of the USA 93, 11939-11944.
27. A receptors to synaptic and extrasynaptic membranes of cerebellar granule cells. Journal of Neuroscience 18, 1693-1703.
28. A receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons. Neuroscience 49, 13-32.
29. A receptor α-subunit mRNAs in the developing rat CNS. Journal of Neuroscience 12, 2888-2900.
30. A receptor stimulation. Journal of Neurochemistry 68, 631-639.
31. REICHLING, D. B., KYROZIS, A., WANG J. & MACDERMOTT, A. B. (1994). Mechanisms of GABA and glycine depolarization-induced calcium transients in rat dorsal horn neurons. Journal of Physiology 476, 411-421.
32. SCIANCALEPORE, M., SAVIC, N., GYOKI, J. & CHERUBINI, E. (1998). Facilitation of miniature GABAergic currents by ruthenium red in neonatal rat hippocampal neurons. Journal of Neurophysiology 80, 2316-2322.
33. - channels in embryonic rat spinal and olfactory bulb cells. Journal of Physiology 488, 371-386.
34. TAMAS, G., BUHL, E. H. & SOMOGYI, P. (1997). Fast IPSPs elicited via multiple synaptic release sites by different types of GABAergic neurone in the cat visual cortex. Journal of Physiology 500, 715-738.
35. A receptor α6 subunit. Journal of Neuroscience 16, 3630-3640.
36. TRAUB, R. D., WHITTINGTON, M. A., COLLING, S. B., BUZSAKI, G. & JEFFERYS, J. G. (1996). Analysis of gamma rhythms in the rat hippocampus in vitro and in vivo. Journal of Physiology 493, 471-484.
37. TRUDEAU, L. E., DOYLE, R. T., EMERY, D. G. & HAYDON, P. G. (1996). Calcium-independent activation of the secretory apparatus by ruthenium red in hippocampal neurons: a new tool to assess modulation of presynaptic function. Journal of Neuroscience 16, 46-54.
38. 1 changes in the dendrites of hippocampal CA1 pyramidal neurons. Journal of Neurophysiology 76, 2896-2906.
39. VERDOORN, T. A. (1994). Formation of heteromeric γ-aminobutyric acid type A receptors containing two different α subunits. Molecular Pharmacology 45, 475-480.
40. VERDOORN, T. A., DRAGUHN, A., YMER, S., SEEBURG, P. H. & SAKMANN, B. (1990). Functional properties of recombinant rat GABAA receptors depend upon subunit composition. Neuron 4, 919-928.
41. WANG, J., MORLEY, P., BEGIN-HEICK, N. & WHITFIELD, J. (1995). Do pancreatic islet cells from neonatal rats have surface receptors or sensors for divalent cations? Cellular Signalling 7, 651-658.
42. WANG, X. J. & BUZSAKI, G. (1996). Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model. Journal of Neuroscience 16, 6402-6413.
43. WHITTINGTON, M. A., TRAUB, R. D. & JEFFERYS, J. G. (1995). Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation. Nature 373, 612-615.
44. A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. Journal of Neuroscience 12, 1040-1062.
45. A receptor-mediated currents in interneurons and pyramidal cells of rat visual cortex. Journal of Physiology 506, 715-730.
46. 2+ influx in developing neocortex by excitatory and inhibitory neurotransmitters. Neuron 6, 333-344.