Functional anatomy of verbal fluency in people with schizophrenia and those at genetic risk. Focal dysfunction and distributed disconnectivity reappraised

British Journal of Psychiatry

Volumn 176, Issue JAN., 2000, Pages 52-60

  Spence, Sean A ^a,g   Liddle, Peter F ^b   Stefan, Martin D ^c   Hellewell, Jonathan S E ^d   Sharma, Tonmoy ^c   Friston, Karl J ^e   Hirsch, Steven R ^f   Frith, Christopher D ^e   Murray, Robin M ^c   Deakin, J F William ^d   Grasby, Paul M ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e WELLCOME TRUST CENTRE FOR NEUROIMAGING   (United Kingdom)

^f CHARING CROSS HOSPITAL   (United Kingdom)

^g WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN SCINTISCANNING; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FUNCTIONAL ANATOMY; GENETIC RISK; HUMAN; MALE; NEUROANATOMY; PREFRONTAL CORTEX; SCHIZOPHRENIA; SPEECH INTELLIGIBILITY; TEMPORAL CORTEX;

HETEROZYGOTE; HUMANS; MALE; PREFRONTAL CORTEX; SCHIZOPHRENIA; SPEECH DISORDERS; TEMPORAL LOBE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0033957950     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.176.1.52     Document Type: Article

References (33)

1. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM-IV). Washington, DC: APA.
2. Andreasen, N. C., Endicott, J., Spitzer, R. L., et al (1977) The family history method using diagnostic criteria. Reliability and validity. Archives of General Psychiatry, 34, 1299-1235.
3. Crespo-Facorro, B., Paradiso, S., Andreasen, N. C., et al (1999) Recalling word lists reveals 'cognitive dysmetria' in schizophrenia: a positron emission tomography study. American Journal of Psychiatry, 156, 386-392.
4. Crow, T. J. (1997) Schizophrenia as failure of hemispheric dominance for language. Trends in Neuroscience, 20, 339-343.
5. Deakin, J. F. W., Slater, P., Simpson, M. D. C., et al (1989) Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia. Journal of Neuroschemistry, 52, 1781-1786.
6. Devinsky, O., Morrell, M. J. & Vogt, B. A. (1995) Contribution of anterior cingulate cortex to behaviour. Brain, 118, 279-306.
7. Dolan, R. J., Fletcher, P., Frith, C. D., et al (1996) Dopaminergic modulation of impaired cognitive activation in the anterior cingulate cortex in schizophrenia. Nature, 378, 180-182.
8. Dye, S. M., Spence, S. A., Bench, C. J., et al (1999) No evidence for left superior temporal dysfunction in asymptomatic schizophrenia and bipolar disorder. PET study of verbal fluency. British Journal of Psychiatry, 175, 367-374.
9. Erkwoh, R., Sabri, O., Steinmeyer, E. M., et al (1997) Psychopathological and SPECT findings in never-treated schizophrenia. Acta Psychiatrica Scandinavica, 96, 51-57.
10. Fletcher, P. C., Frith, C. D., Grasby, P. M., et al (1996) Local and distributed effects of apomorphine upon fronto-temporal function in acute unmedicated schizophrenia. Journal of Neuroscience, 16, 7055-7062.
11. _, McKenna P. J., Frith, C. D., et al (1998) Brain activations in schizophrenia during a graded memory task studied with functional neuroimaging. Archives of General Psychiatry, 55, 1001-1008.
12. _, _, Friston, K. J., et al (1999) Abnormal cingulate modulation of fronto-temporal connectivity in schizophrenia. Neuroimage, 9, 337-342.
13. Friston, K. J., Passingham, R. E., Nutt, J. G., et al (1989) Localisation in PET images: direct fitting of the intercommissural (AC-PC) line.Journal of Cerebral Blood Flow and Metabolism, 9, 690-695.
14. _, Frith, C. D., Liddle, P. F., et al (1991) Investigating a network model of word generation with positron emission tomography. Proceedings of the Royal Society of London. Series B: Biological Sciences, 244, 101-106.
15. _, Herold, S., Fletcher, P., et al (1995a) Abnormal fronto-temporal interactions in schizophrenia. In Biology of Schizophrenia and Affective Diseases (ed. S. J. Watson), pp. 449-481. New York: Raven.
16. _, Holmes, A. P. & Worsley, K. J. (1995b) Statistical parametric maps in functional imaging: a general linear approach. Human Brain Mapping, 2, 189-210.
17. Frith, C. D., Friston, K. J., Liddle, P. F., et al (1991a) A PET study of word finding. Neuropsychologia, 29, 1137-1148.
18. _, _, _, et al (1991b) Willed action and the prefrontal cortex in man: a study with PET. Proceedings of the Royal Society of London. Series B: Biological Sciences, 244, 241-246.
19. _, _ , Herold, S., et al (1995) Regional brain activity in schizophrenic patients during the performance of a verbal fluency task. British Journal of Psychiatry, 167, 343-349.
20. Krasucki, C. & McFarlane, F. (1996) Electrocardiograms, high-dose antipsychotic treatment and College guidelines. Psychiatric Bulletin, 20, 326-330.
21. Krawiecka, M., Goldberg, D. & Vaughan, M. (1977) A standardised psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatrica Scandinavica, 55, 299-308.
22. Nelson, H. E. & O'Connell, A. (1978) Dementia: the estimation of premorbid intelligence levels using the New Adult Reading Test. Cortex, 14, 234-244.
23. O'Leary, D. S., Andreasen, N. C., Hurtig, R. R., et al (1997) Auditory and visual attention assessed with PET. Human Brain Mapping, 5, 422-436.
24. 15O regional cerebral blood flow three-dimensional imaging technique. Journal of Cerebral Blood Flow and Metabolism, 13, 617-629.
25. Spence, S. A., Hirsch, S. R., Brooks, D. J., et al (1998) Prefrontal cortex activity in people with schizophrenia and control subjects. Evidence from positron emission tomography for remission of 'hypofrontality' with recovery from acute schizophrenia. British Journal of Psychiatry, 172, 316-323.
26. _ & Frith, C. D. (1999) Towards a functional anatomy of volition. Journal of Consciousness Studies, 6, 11-28.
27. Talairach, J. & Tournoux, P. (1988) Co-planar Stereotactic Atlas of the Human Brain. Stuttgart: Thieme.
28. Warburton, E., Wise, R. J. S., Price, C. J., et al (1996) Noun and verb retrieval by normal subjects: studies with positron emission tomography. Brain, 119, 159-179.
29. Weinberger, D. R., Berman, K. F., Suddath, R., et al (1992) Evidence of dysfunction of a prefrontal - limbic network in schizophrenia: a magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. American Journal of Psychiatry, 149, 890-897.
30. _ & _ (1994) Prefrontal function in schizophrenia: confounds and controversies. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 351, 1495-1503.
31. Woodruff, P. W. R., Wright, I. C., Bullmore, E.T., et al (1997) Auditory hallucinations and the temporal cortical response to speech in schizophrenia: a functional magnetic resonance imaging study. American Journal of Psychiatry, 154, 1676-1682.
32. Woods, R. P., Cherry, S. R. & Mazziotta, J. C. (1992) Rapid automated algorithm for aligning and reslicing PET images. Journal of Computer Assisted Tomography, 16, 620-633.
33. Yang, C. R., Seamans, J. K. & Gorelova, N. (1999) Developing a neuronal model for the pathophysiology of schizophrenia based on the nature of electrophysiological actions of dopamine in the prefrontal cortex. Neuropsychopharmacology, 21, 161-194.