Psychopathological and spect findings in never-treated schizophrenia

Acta Psychiatrica Scandinavica

Volumn 96, Issue 1, 1997, Pages 51-57

  Erkwoh, R ^a   Sabri, O ^a   Steinmeyer, E M ^a   Bull U ^a   Sass H ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Cerebral blood flow; Schizophrenia

Indexed keywords

HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M;

ADULT; ARTICLE; BRAIN BLOOD FLOW; CLINICAL ARTICLE; CONTROLLED STUDY; DELUSION; FEMALE; FRONTAL CORTEX; HALLUCINATION; HUMAN; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SYMPTOMATOLOGY; TEMPORAL CORTEX; THOUGHT DISORDER;

EID: 0030802701     PISSN: 0001690X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0447.1997.tb09904.x     Document Type: Article

References (35)

1. CHUA SE, MCKENNA PJ. Schizophrenia - a brain disease? Br J Psychiatry 1995: 166: 563-582.
2. INGVAR DH, FRANZÉN G. Abnormalities of cerebral blood flow distribution in patients with chronic schizophrenia. Acta Psychiatr Scand 1974: 50: 425-462.
3. SAGAWA K, KAWAKATSU S, SHIBUYA I et al. Correlation of cerebral blood flow with performance on neuropsychological tests in schizophrenic patients. Schizophr Res 1990: 3: 241-246.
4. VOLKOW ND, WOLF AP, VAN GELDER P et al. Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia. Am J Psychiatry 1987: 144: 151-158.
5. COHEN RM, SEMPLE WE, GROSS M et al. Dysfunction in a prefrontal substrate of sustained attention in schizophrenia. Life Sci 1987: 40: 2031-2039.
6. WARKENTIN S, NILSSON A, RISBERG J et al. Regional cerebral blood flow in schizophrenia: repeated studies during a psychotic episode. Psychiatr Res Neuroimag 1990: 35: 27-38.
7. RUBIN P, HOLM S, FRIBERG L et al. Altered modulation of prefrontal and subcortical brain activity in newly diagnosed schizophrenia and schizophreniform disorder. Arch Gen Psychiatry 1991: 48: 987-995.
8. ANDREASEN NC, REZAI K, ALLIGER R et al. Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Arch Gen Psychiatry 1992: 49: 943-958.
9. 99mTc-exametazime in unmedicated schizophrenic patients. Biol Psychiatry 1993: 33: 487-495.
10. WIESEL FA, WIK G, SJÖGREN G, BLOMQVIST G, GREITZ T, STONE-ELANDER S. Regional brain glucose metabolism in drug-free schizophrenic patients and clinical correlates. Acta Psychiatr Scand 1987: 76: 628-641.
11. FRANZÉN G, INGVAR DH. Absence of activation in frontal structures during psychological testing of chronic schizophrenics. J Neurol Neurosurg Psychiatry 1975: 38: 1027-1032.
12. WEINBERGER DR, BERMAN KF, ZEC RF. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch Gen Psychiatry 1986: 43: 114-124.
13. PAULMAN RG, DEVOUS MD, GREGORY RR et al. Hypofrontality and cognitive impairment in schizophrenia: dynamic single-photon tomography and neuropsychological assessment of schizophrenic brain function. Biol Psychiatry 1990: 27: 377-399.
14. 99mTc-HMPAO single-photon emission ranging in chronic schizophrenia. Psychol Med 1992: 22: 27-35.
15. WOLKIN A, SANFILIPO M, WOLF AP, ANGRIST B, BRODIE JD, ROTROSEN J. Negative symptoms and hypofrontality in chronic schizophrenia. Arch Gen Psychiatry 1992: 49: 959-965.
16. BERMAN KF, ZEC RF, WEINBERGER DR. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Role of neuroleptic treatment, attention, and mental effort. Arch Gen Psychiatry 1986: 43: 126-135.
17. SZECHTMAN H, NAHMIAS C, GARNETT S et al. Effect of neuroleptics on altered cerebral glucose metabolism in schizophrenia. Arch Gen Psychiatry 1988: 45: 523-532.
18. VOLKOW ND, BRODIE JD, WOLF AP, ANGRIST B, RUSSELL J, CANCRO R. Brain metabolism in patients with schizophrenia before and after acute neuroleptic administration. J Neurol Neurosurg Psychiatry 1986: 49: 1199-1202.
19. CLEGHORN JM, GARNETT ES, NAHMIAS C et al. Increased frontal and reduced parietal glucose metabolism in acute untreated schizophrenia. Psychiatr Res 1989: 28: 119-133.
20. 99mHMPAO-SPECT patterns in young neuroleptic-naive patients with acute disease. J Nucl Med 1994: 35: 935-941.
21. 99m-hexamethylpropyleneamineoxime. Acta Psychiatr Scand 1989: 80: 427-433.
22. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, revised 3rd edn. Washington, DC: American Psychiatric Press, 1987.
23. CROW TJ. The two-syndrome concept: origins and current status. Schizophr Bull 1985: 11: 471-485.
24. KAY SR, FISZBEIN A, OPLER LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987: 13: 261-276.
25. HAWTON K, SHEPSTONE B, SOPER N, REZNEK L. Single-photon emission computerised tomography (SPECT) in schizophrenia. Br J Psychiatry 1990: 156: 425-427.
26. CANTOR-GRAAE E, WARKENTIN S, FRANZÉN G, RISBERG J, INGVAR DH. Aspects of stability of regional cerebral blood flow in chronic schizophrenia: an 18-year follow-up study. Psychiatr Res 1991: 40: 253-266.
27. DEVOUS MD SR. Imaging brain function by single-photon emission computer tomography. In: ANDREASEN NC, ed. Brain imaging: applications in psychiatry. Washington, DC: American Psychiatric Press, 1989: 147-234.
28. SYED GMS, BARRET JJ, TOONE BK. What does rCBF SPECT offer in schizophrenia? Nucl Med Commun 1992: 13: 879-884.
29. MELLERS JDC, SHAM P, JONES PB, TOONE BK, MURRAY RM. A factor analytic study of symptoms in acute schizophrenia. Acta Psychiatr Scand 1996: 93: 92-98.
30. BLEULER E. Dementia präcox oder die Gruppe der Schizophrenien. Leipzig: Deuticke, 1911.
31. KWAPIL TR, HEGLEY DC, CHAPMAN LJ, CHAPMAN JP. Facilitation of word recognition by semantic priming in schizophrenia. J Abnorm Psychol 1990: 99: 215-221.
32. GLOOR P. Role of human limbic system in perception, memory, and affect: lessons from temporal lobe epilepsy. In: DOANE BK, LIVINGSTON KE, ed. The limbic system. Functional organization and clinical disorders. New York: Raven Press, 1986: 159-169.
33. FUSTER J. The prefrontal cortex. New York: Raven Press, 1989.
34. ARNDT S, ALLIGER RJ, ANDREASEN NC. The distinction of positive and negative symptoms. The failure of a two-dimensional model. Br J Psychiatry 1991: 61: 303-321.
35. LIDDLE PF, FRISTON KJ, FRITH CD, HIRSCH SR, JONES T, FRACKOWIAK RSJ. Patterns of cerebral blood flow in schizophrenia. Br J Psychiatry 1992: 160: 179-186.