Cyclosporin A decreases the degradation of type I collagen in rat gingival overgrowth

Journal of Cellular Physiology

Volumn 182, Issue 3, 2000, Pages 351-358

  Kataoka, Masatoshi ^a   Shimizu, Yasuki ^a   Kunikiyo, Kenji ^a   Asahara, Yoji ^a   Yamashita, Kikuji ^a   Ninomiya, Masami ^a   Morisaki, Ichijiro ^b   Ohsaki, Yasuyoshi ^c   Kido, Jun Ichi ^a   Nagata, Toshihiko ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; CYCLOSPORIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN DEGRADATION; COLLAGEN METABOLISM; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; GINGIVA OVERGROWTH; MALE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CELL DIVISION; CELLS, CULTURED; COLLAGEN; COLLAGENASES; CYCLOSPORINE; FIBROBLASTS; GENE EXPRESSION; GINGIVA; GINGIVAL OVERGROWTH; IMMUNOSUPPRESSIVE AGENTS; LATEX; MALE; MICROSCOPY, ELECTRON; MICROSPHERES; PHAGOCYTOSIS; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 0033957168     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(200003)182:3<351::AID-JCP5>3.0.CO;2-U     Document Type: Article

References (43)

1. Amendola A, Lombardi G, Oliverio S, Colizzi V, Piacentini M. 1994. HIV-1 gp120-dependent induction of apoptosis in antigen-specific human T cell clones is characterized by "tissue" transglutaminase expression and prevented by cyclosporin A. FEBS Lett 339:258-264.
2. Antman EM, Stone PH, Muller JE, Braunswald E. 1980. Calcium channel blocking agents in the treatment of cardiovascular disorders. Part 1. Basic clinical electrophysiologic effects. Ann Intern Med 93:875-885.
3. Bennet JA, Christian JM. 1982. Cyclosporin-induced gingival hyperplasia. A case report and literature review. J Am Dent Assoc 111: 272-273.
4. Cheryl OQ, Donald KS, Constance EB, Lynn MM, John JJ, Nicola CP. 1990. Rat collagenase. J Biol Chem 265:22342-22347.
5. Creemers LB, Hoeben KA, Jansen DC, Buttle DJ, Beertsen W, Everts V. 1998. Participation of intracellular cystein proteinases, in particular cathepsin B, in degradation of collagen in periosteal tissue explants. Matrix Biol 16:575-584.
6. Deliliers GL, Santoro F, Poli N, Bruno E, Fumagalli L, Risciotti E. 1986. Light and electron microscopic study of cyclosporin A-induced gingival hyperplasia. J Periodontol 57:771-775.
7. 2+ levels. J Cell Biol 106:657-666.
8. Everts V, Beertsen W, Tigchelaar-Gutter W. 1985. The digestion of phagocytosed collagen is inhibited by the proteinase inhibitors leupeptin and E-64. Coll Relat Res 5:315-336.
9. Everts V, Wolvius E, Saklatvala J, Beertsen W. 1990. Interleukin 1 increases the production of collagenase but does not influence the phagocytosis of collagen fibrils. Matrix 10:388-393.
10. Everts V, Van der Zee E, Creemers L, Beertsen W. 1996. Phagocytosis and intracellular digestion of collagen, its role in turnover and remodelling. Histochem J 28:229-245.
11. Genovese C, Rowe D, Kream B. 1984. Construction of DNA sequences complementary to rat α1 and α2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D. Biochemistry 23:6210-6216.
12. Goultschin J, Shoshan S. 1980. Inhibition of collagen breakdown by diphenylhydantoin. Biochim Biophys Acta 631:188-191.
13. Hall BK, Squier CA. 1982. Ultrastructural quantitation of connective tissue changes in phenytoin-induced gingival overgrowth in the ferret. J Dent Res 61:942-952.
14. Hassell TM, Hefti AF. 1991. Drug-induced gingival overgrowth:old problem, new problem. Crit Rev Oral Biol Med 2:103-137.
15. James JA, Irwin CR, Linden GJ. 1995. The effects of culture environment on the response of human gingival fibroblasts to cyclosporin A. J Periodontol 66:339-344.
16. Korn JH, Thrall RS, Wilbar DC, Kream BE, Piela-Smith TH. 1992. Fibroblast heterogeneity:clonal selection of fibroblasts as a model for fibrotic disease. In:Philipps RP, editor. Pulmonary fibroblast heterogeneity. Boca Raton, FL:CRC Press. p 119-133.
17. Layman DL, Diedrich DL. 1987. Growth inhibitory effects of endotoxins from Bacteroides gingivalis and intermedius on human gingival fibroblasts. J Periodontol 58:387-392.
18. Lee W, Sodek J, McCulloch CAG. 1996. Role of integrins in regulation of collagen phagocytosis by human fibroblasts. J Cell Physiol 168: 695-704.
19. McCulloch CAG, Knowles GC. 1993. Deficiencies in collagen phagocytosis by human fibroblasts in vitro:a mechanism for fibrosis? J Cell Physiol 155:461-471.
20. McGaw WT, Porter H. 1988. Cyclosporin-induced gingival overgrowth:an ultrastructural stereologic study. Oral Surg Oral Med Oral Pathol 65:186-190.
21. McKeown M, Knowles G, McCulloch CAG. 1990. Role of the cellular attachment domain of fibronectin in the phagocytosis of beads by human gingival fibroblasts in vitro. Cell Tiss Res 262:523-536.
22. Messing RO, Carpenter CL, Greenberg DA. 1985. Mechanism of calcium channel inhibition by nifedipine:comparison with classical calcium channel antagonists. J Pharmacol Exp Ther 235:407-411.
23. Murphy G, Reynolds JJ. 1984. Current views of collagen degradation: progress towards understanding the resorption of connective tissues. Bioessays 2:55-60.
24. Nishikawa S, Nagata T, Morisaki I, Oka T, Ishida H. 1996. Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model. J Periodontol 67:463-471.
25. Ohsaki Y, Nagata K. 1994. Type III collagen is a major component of interodontoblastic fibers of the developing mouse molar root. Anat Rec 240:308-313.
26. Perez-Tamayo R. 1978. Pathology of collagen degradation. Am J Pathol 92:509-566.
27. Robinson MQ, Simon MI. 1991. Determining transcript number using the polymerase chain reaction:Pgk-2, mP2, and PGK-2 transgene mRNA levels during spermatogenesis. Nucleic Acids Res 19:1557-1562.
28. Rostock MH, Fry HR, Turner JE. 1985. Severe gingival overgrowth associated with cyclosporine therapy. J Periodontol 57:294-299.
29. Ruoslahti E, Reed JC. 1994. Anchorage dependence, integrins, and apoptosis. Cell 77:477-478.
30. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular Cloning:A Laboratory Manual. 2nd ed. Cold Spring Harbor, NY:Cold Spring Harbor Laboratory. 9.38-9.40.
31. Savage NW, Seymour GJ, Robinson MF. 1986. Cyclosporin-A-induced gingival enlargement. J Periodontol 58:475-480.
32. Schincaglia GP, Forniti F, Cavallini R, Calura G, del Senno L. 1992. Cyclosporin-A increases type I procollagen production and mRNA level in human gingival fibroblasts in vitro. J Oral Pathol Med 21:181-185.
33. Shevach EM. 1985. The effects of cyclosporin A on the immune system. Annu Rev Immunol 3:397-423.
34. Sodek J, Overall C. 1988. Matrix degradation in hard and soft connective tissue. In:Davidovitch Z, editor. The biological mechanisms of tooth eruption and root resorption. Birmingham, AL:EBSCO. p 303-312.
35. Sugano N, Ito K, Murai S. 1998. Cyclosporin A inhibits collagenase gene expression via AP-1 and JNK suppression in human gingival fibroblasts. J Periodont Res 33:448-452.
36. Thomason JM, Sloan P, Seymour RA. 1998. Immunolocalization of collagenase (MMP-1) and stromelysin (MMP-3) in the gingival tissues of organ transplants medicated with cyclosporin. J Clin Periodontol 25:554-560.
37. Tipton DA, Stricklin GA, Dabbous MKh. 1991. Fibroblast heterogeneity in collagenolytic response to cyclosporine. J Cell Biochem 46:152-165.
38. Van der Zee E, Everts V, Beertsen W. 1997. Cytokines modulate routes of collagen breakdown. J Clin Periodontol 24:297-305.
39. Willershausen-Zönnchen B, Lemmen C, Schumacher U. 1992. Influence of cyclosporine A on growth and extracellular matrix synthesis of human fibroblasts. J Cell Physiol 152:397-402.
40. Wong WSF, Luk JM. 1997. Signalling mechanisms of pertussis toxin-induced myelomonocytic cell adhesion:role of tyrosine phosphorylation. Biochem Biophys Res Commun 236:479-482.
41. Wysocki GP, Gretzinger HA, Laupacis A. 1983. Fibrous hyperplasia of the gingiva:a side effect of cyclosporin A therapy. Oral Surg Oral Med Oral Pathol 55:274-278.
42. Yamasaki A, Rose GG, Pinero GJ, Mahan CJ. 1987. Ultrastructure of fibroblasts in cyclosporine A-induced gingival hyperplasia. J Oral Pathol 16:129-134.
43. Yamashita K, Takagi T. 1992. Ultrastructural observation of calcification preceding new bone formation induced by demineralized bone matrix gelatin. Acta Anat 143:261-267.