The eyes have it: Mouse retinal degenerations symposium and workshop

Molecular Medicine

Volumn 6, Issue 2, 2000, Pages 51-53

  Hauswirth, William W ^a   Timmers, Adrian M ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFERENCE PAPER; GENE TECHNOLOGY; GENE THERAPY; HUMAN; NIGHT BLINDNESS; RETINA DEGENERATION; RETINA MACULA DEGENERATION; RETINITIS PIGMENTOSA;

ANIMALS; DISEASE MODELS, ANIMAL; GENE THERAPY; HUMAN GENOME PROJECT; HUMANS; MACULAR DEGENERATION; MICE; MICE, INBRED STRAINS; NIGHT BLINDNESS; PHENOTYPE; RETINAL DISEASES; RETINITIS PIGMENTOSA;

EID: 0033956986     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (11)

1. Klein, R. et al. (1997) The five-year incidence and progression of age-related maculopathy. Ophthalmology 104, 7-21
2. Reme, C.E. et al. (1998) Apoptotic cell death in retinal degenerations. Prog. Retinal Eye Res. 17, 443-464
3. Bech-Hansen, N.T. et al. (1999) Loss-of-function mutations in a calcium-channel alpha1-subunit gene in Xp11.23 cause incomplete congenital stationary night blindness. Nat. Genet. 19, 264-267
4. Weng, J. et al. (1999) Insights into the function of Rim protein in photoreceptors of Statgardt's disease from the phenotype of the abcr knockout mouse. Cell 98, 13-23
5. Bowes, C. et al. (1990) Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of the rod cGMP-phosphodiesterase. Nature 347, 677-680
6. Bennett, J. et al. (1996) Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy. Nat. Med. 2, 649-654
7. Kumar-Singh, R. and Farber, D.B. (1998) Encapsidated adenovirus mini-chromosome-mediated delivery of genes to the retina: application to the rescue of photoreceptor degeneration. Hum. Mol. Genet 7, 1893-1900
8. Cayouette, M. et al. (1998) Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse. J. Neurosci. 18, 9282-9293
9. Cayouette, M. and Gravel, C. (1997) Adenovirus-mediated gene transfer of ciliary neurotrophic factor can prevent photoreceptor degeneration in the retinal degeneration (rd) mouse. Hum. Gene Ther. 8, 423-430
10. Lewin, A.S. et al. (1998) Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa. Nat. Med. 4, 967-971
11. Bennett, J. et al. (1999) Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina. Proc. Natl. Acad. Sci. U. S. A. 96, 9920-9925