L-DOPA cyclohexyl ester is a novel potent and relatively stable competitive antagonist against L-DOPA among several L-DOPA ester compounds

Japanese Journal of Pharmacology

Volumn 82, Issue 1, 2000, Pages 40-47

  Furukawa, Nobuya ^a   Goshima, Yoshio ^a   Miyamae, Takeaki ^a   Sugiyama, Yoshinobu ^a   Shimizu, Minako ^b   Ohshima, Etsuo ^c   Suzuki, Fumio ^c   Arai, Nobutaka ^d   Fujita, Kiyohide ^a   Misu, Yoshimi ^a,e  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c KYOWA HAKKO KOGYO CO LTD   (Japan)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^e Shinobu Hospital   (Japan)

Author keywords

Competitive L DOPA antagonist; DOPA cyclohexyl ester; Glutamatergic and dopaminergic binding; Nucleus accumbens; Nucleus tractus solitarii

Indexed keywords

2 AMINO 4 PHOSPHONOMETHYL 3 HEPTENOIC ACID; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; DIZOCILPINE; KAINIC ACID; LEVODOPA; LEVODOPA CYCLOHEXYL ESTER; LEVODOPA CYCLOPENTYL ESTER; LEVODOPA CYCLOPENTYLDIMENTHYL ESTER; LEVODOPA METHYL ESTER; SPIPERONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; DRUG ANTAGONISM; HYPOTENSION; LIGAND BINDING; MALE; NONHUMAN; NUCLEUS ACCUMBENS; RAT; SOLITARY TRACT NUCLEUS;

EID: 0033956471     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.82.40     Document Type: Article

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