Partial rescue of the ocular retardation phenotype by genetic modifiers

Journal of Neurobiology

Volumn 42, Issue 2, 2000, Pages 232-247

  Bone Larson, Cynthia ^a   Basu, Sharmila ^b   Radel, Jeffrey D ^c   Liang, Meiying ^a   Perozek, Timothy ^a   Kapousta Bruneau, Natalia ^d   Green, Daniel G ^d   Burmeister, Margit ^b   Hankin, Mark H ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Chx10 homeobox gene; Microphthalmia; Mouse; Optic nerve; Retina

Indexed keywords

ALLELE; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; ELECTRORETINOGRAM; EMBRYO; FETUS; GENE; HOMEOBOX; IMMUNOHISTOCHEMISTRY; MICROPHTHALMIA; MORPHOMETRICS; MOUSE; NEWBORN; NONHUMAN; OPTIC NERVE; PHENOTYPE; PRIORITY JOURNAL; RETINA; RETINA DEVELOPMENT;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CILIARY BODY; CROSSES, GENETIC; ELECTRORETINOGRAPHY; EYE; HOMEODOMAIN PROTEINS; IRIS; LENS, CRYSTALLINE; MICE; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; MICROPHTHALMOS; OPTIC NERVE; PHENOTYPE; REFLEX, PUPILLARY; RETINA; TRANSCRIPTION FACTORS;

EID: 0033954738     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4695(20000205)42:2<232::AID-NEU7>3.0.CO;2-4     Document Type: Article

References (32)

1. Adams JC. 1981. Heavy metal intensification of DAB-based HRP reaction product. J Histochem Cytochem 29:775.
2. Bao Z-Z, Cepko CL. 1997. The expression and function of Notch pathway genes in the developing rat eye. J Neurosci 17:1425-1434.
3. Barnstable CJ. 1980. Monoclonal antibodies which recognize different cell types in rat retina. Nature 286:231.
4. Barnstable CJ, Akagawa K, Hofstein R, Horn JP. 1983. Monoclonal antibodies that label discrete cell types in the mammalian nervous system. Cold Spring Harb Symp Quant Biol 48:863-876.
5. Brittis PA, Canning DR, Silver J. 1992. Chondroitin sulfate as a regulator of neuronal patterning in the retina. Science 255:733-736.
6. Brittis PA, Silver J. 1994. Exogenous glycosaminoglycans induce complete inversion of retinal ganglion cell bodies and their axons within the retinal neuroepithelium. Proc Natl Acad Sci USA 91:7539-7542.
7. Brittis PA, Silver J. 1995. Multiple factors govern intraretinal axon guidance: a time-lapse study. Mol Cell Neurosci 6:413-432.
8. Burmeister M, Novak J, Liang M-Y, Basu S, Ploder L, Hawes NL, Vidgen D, Hoover F, Goldman D, Kalnins VI, Roderick TH, Taylor BA, Hankin MH, McInnes RR. 1996. Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation. Nat Genet 12:376-384.
9. Doi M, Uji Y, Yamamura H. 1995. Morphological classification of retinal ganglion cells in mice. J Comp Neurol 356:368-386.
10. Dreher B, Sefton AJ, Ni SYK, Nisbett G. 1985. The morphology, number, distribution and central projections of class I retinal ganglion cells in albino and hooded rats. Brain Behav Evol 26:10-48.
11. Fantl V, Stamp G, Andrews A, Rosewell I, Dickson C. 1995. Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. Genes Dev 9:2364-2372.
12. Freund C, Horsford DJ, McInnes RR. 1996. Transcription factor genes and the developing eye: a genetic perspective. Hum Mol Genet 5:1471-1488.
13. Greferath U, Grünert U, Wässle H. 1990. Rod bipolar cells in the mammalian retina show protein kinase C-like immunoreactivity. J Comp Neurol 301:433-442.
14. Hogan B, Costantini F, Lacy E. 1986. Manipulating the mouse embryo: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. 497 p.
15. 1 phase. Experientia 27:970-971.
16. Konyukhov BV, Sazhina MV. 1975. Inhibition of DNA synthesis in embryonic mouse retina as a result of gene interaction. Dev Biol 45:1-6.
17. Liang M-Y, Hankin MH. 1995. Retinal ganglion cell differentiation in ocular retardation mice. Soc Neurosci Abstr 21:31.
18. Liu ISC, Chen JD, Ploder L, Vidgen D, Van der kooy D, Kalnins VI, Mclnnes RR. 1994. Developmental expression of a novel murine homeobox gene (chx10): evidence for roles in determination of the neuroretina and inner nuclear layer. Neuron 13:377-393.
19. Monaghan AP, Davidson DR, Sime C, Graham E, Baldock R, Bhattacharya SS, Hill RE. 1991. The Msh-like homeobox genes define domains in the developing vertebrate eye. Development 112:1053-1061.
20. Negishi K, Kato S, Teranishi T. 1988. Dopamine cells and rod bipolar cells contain protein kinase C-like immunoreactivity in some vertebrate retinas. Neurosci Lett 94: 247-252.
21. Perry VH. 1979. The ganglion cell layer of the retina of the rat: a Golgi study. Proc R Soc Lond B 204:363-375.
22. Radel JD, Kustra DJ, Das S, Elton S, Lund RD. 1995. The pupillary light response: assessment of function mediated by intracranial retinal transplants. Neuroscience 68:909-924.
23. Robb M, Silver J, Sullivan R. 1978. Ocular retardation (or) in the mouse. Invest Ophthalmol Vis Sci 17:468-473.
24. Sicinski P, Donaher JL, Parker SB, Li T, Fazeli A, Gardner H, Haslam SZ, Bronson RT, Elledge SJ, Weinberg RA. 1995. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell 82:621-630.
25. Silver J, Hughes AFW. 1974. The role of cell death during morphogenesis of the mammalian eye. J Morphol 140: 159-170.
26. Silver J, Robb RM. 1979. Studies on the development of the eye cup and optic nerve in normal mice and in mutants with congenital optic nerve aplasia. Dev Biol 68:175-190.
27. Snow DM, Watanabe M, Letourneau PC, Silver J. 1991. A chondroitin sulfate proteoglycan may influence the direction of retinal ganglion cell outgrowth. Development 113:1473-1485.
28. Soriano E, Delrio JA, Martinez-Guijarro FJ, Ferrer I, Lopez C. 1991. Immunocytochemical detection of 5′-bromodeoxyuridine in fluoro-gold-labeled neurons - a simple technique to combine retrograde axonal tracing and neurogenetic characterization of neurons. J Histochem Cytochem 39:1565-1570.
29. Steinberg RH, Frishman LJ, Sieving PA. 1991. Negative components of the electroretinogram from proximal retina and photoreceptor. Prog Ret Res 10:121-160.
30. Theiler K, Varnum DS, Nadeau JH, Stevens LC, Cagianut B. 1976. A new allele of ocular retardation: early development and morphogenetic cell death. Anat Embryol 150:85-97.
31. Truslove GM. 1962. A gene causing ocular retardation in the mouse. J Embryol Exp Morphol 10:652-660.
32. Watanabe M, Rutishauser U, Silver J. 1990. Formation of the retinal ganglion cell and optic fiber layers. J Neurobiol 22:85-96.