Inhibition of endosome fusion in primary hepatocytes prevents asialoglycoprotein degradation but not uptake of transferrin iron demonstrating that intracellular iron release occurs from early endosomes

FEBS Letters

Volumn 466, Issue 1, 2000, Pages 135-138

  Young, Stephen P ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Asialoglycoprotein receptor; Bromophenacyl bromide; Endocytosis; Endosome fusion; Hepatocyte; Iron; Phospholipase A2; Transferrin

Indexed keywords

4 BROMOPHENACYL BROMIDE; ASIALOGLYCOPROTEIN; IRON; PHOSPHOLIPASE A2; TRANSFERRIN;

ANIMAL CELL; ARTICLE; CELL FUSION; CYTOPLASM; ENDOCYTOSIS; ENDOSOME; IRON KINETICS; IRON TRANSPORT; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

ACETOPHENONES; ANIMALS; ASIALOGLYCOPROTEINS; BIOLOGICAL TRANSPORT, ACTIVE; ENDOCYTOSIS; ENDOSOMES; ENZYME INHIBITORS; INTRACELLULAR FLUID; IRON; LIVER; MALE; MEMBRANE FUSION; PHOSPHOLIPASES A; POTASSIUM; RATS; RATS, WISTAR; TRANSFERRIN;

EID: 0033954716     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01774-3     Document Type: Article

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