Sequence, genomic organization and functional expression of the murine tRNA-specific adenosine deaminase ADAT1

Gene

Volumn 243, Issue 1-2, 2000, Pages 59-66

  Maas, Stefan ^a   Kim, Yang Gyun ^a   Rich, Alexander ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

ADAR; Exon intron structure; Gene family; RNA editing; tRNA(Ala)

Indexed keywords

ADENOSINE DEAMINASE; TRANSFER RNA;

ARTICLE; GENE EXPRESSION; GENE MAPPING; GENE SEQUENCE; GENE STRUCTURE; GENETIC ORGANIZATION; HUMAN; MULTIGENE FAMILY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA EDITING; SOUTHERN BLOTTING;

NON-PROGRAMMATIC;

ADENOSINE DEAMINASE; ANIMALS; CELL LINE; CLONING, MOLECULAR; DNA; DNA, COMPLEMENTARY; EXONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES; INTRONS; MICE; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; RNA, TRANSFER, ALA; SEQUENCE ANALYSIS, DNA; SUBSTRATE SPECIFICITY;

EID: 0033953566     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00562-4     Document Type: Article

References (18)

1. Bass B.L. RNA editing and hypermutation by adenosine deamination. Trends Biochem. Sci. 22:1997;157-162.
2. Feinberg A.P., Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:1983;6-13.
3. Gerber A., Grosjean H., Melcher T., Keller W. Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2. EMBO J. 17:1998;4780-4789.
4. Grosjean H., Auxilien S., Constantinesco F., Simon C., Corda Y., Becker H.F., Foiret D., Morin A., Jin Y.X., Fournier M., Fourrey J.L. Enzymatic conversion of adenosine to inosine and to N1-methylinosine in transfer RNAs: a review. Biochimie. 78:1996;488-501.
5. Keller W., Wolf J., Gerber A. Editing of messenger RNA precursors and of tRNAs by adenosine to inosine conversion. FEBS Lett. 452:1999;71-76.
6. Kim U., Wang Y., Sanford T., Zeng Y., Nishikura K. Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proc. Natl. Acad. Sci. USA. 91:1994;11 457-11 461.
7. Lai F., Drakas R., Nishikura K. Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts. J. Biol. Chem. 270:1995;17 098-17 105.
8. Maas S., Melcher T., Herb A., Seeburg P.H., Keller W., Krause S., Higuchi M., O'Connell M.A. Structural requirements for RNA editing in glutamate receptor pre-mRNAs by recombinant double-stranded RNA adenosine deaminase. J. Biol. Chem. 271:1996;12 221-12 226.
9. Maas S., Gerber A.P., Rich A. Identification and characterization of a human tRNA-specific adenosine deaminase related to the ADAR family of pre-mRNA editing enzymes. Proc. Natl. Acad. Sci. USA. 96:1999;8895-8900.
10. Maas S., Melcher T., Seeburg P.H. Mammalian RNA-dependent deaminases and edited mRNAs. Curr. Opin. Cell Biol. 9:1997;343-349.
11. Melcher T., Maas S., Herb A., Sprengel R., Higuchi M., Seeburg P.H. RED2, a brain-specific member of the RNA-specific adenosine deaminase family. J. Biol. Chem. 271:1996;31 795-31 798.
12. Mittaz L., Scott H.S., Rossier C., Seeburg P.H., Higuchi M., Antonarakis S.E. Cloning of a human RNA editing deaminase (ADARB1) of glutamate receptors that maps to chromosome 21q22.3. Genomics. 41:1997;210-217.
13. O'Connell M.A., Krause S., Higuchi M., Hsuan J.J., Totty N.F., Jenny A., Keller W. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. Mol. Cell. Biol. 15:1995;1389-1397.
14. Rueter S.M., Emeson R.B. Adenosine-to-inosine conversion in mRNA. Grosjean H., Benne R. Modification and Editing of RNA. 1998;343-361 American Society Microbiology Press, Washington, DC.
15. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
16. Shapiro M.B., Senapathy P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15:1987;7155-7174.
17. Villard L., Tassone F., Haymowicz M., Welborn R., Gardiner K. Map location, genomic organization and expression patterns of the human RED1 RNA editase. Somat. Cell. Mol. Genet. 23:1997;135-145.
18. Wang Y., Zeng Y., Murray J.M., Nishikura K. Genomic organization and chromosomal location of the human dsRNA adenosine deaminase gene: the enzyme for glutamate-activated ion channel RNA editing. J. Mol. Biol. 254:1995;184-195.