Immune-type diversity in the absence of somatic rearrangement

Current Topics in Microbiology and Immunology

Volumn 248, Issue , 2000, Pages 271-282

  Yoder, J A ^a   Litman, G W ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; T LYMPHOCYTE RECEPTOR;

ANTIGEN RECOGNITION; B LYMPHOCYTE; EVOLUTION; FISH; GENE CLUSTER; GENE REARRANGEMENT; GENETIC VARIABILITY; IMMUNOGLOBULIN GENE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SOMATIC MUTATION; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE; VERTEBRATE;

EID: 0033952413     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-59674-2_12     Document Type: Review

References (9)

1. Agrawal A, Eastman QM, Schatz DG (1998) Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 394:744-751
2. Anderson M, Amemiya C, Luer C, Litman R, Rast J, Niimura Y, Litman G (1994) Complete genomic sequence and patterns of transcription of a member of an unusual family of closely related, chro-mosomally dispersed immunoglobulin gene clusters in Raja. Int Immunol 6:1661-1670
3. Anderson MK, Shamblott MJ, Litman RT, Litman GW (1995) The generation of immunoglobulin light chain gene diversity in Raja erinacca is not associated with somatic rearrangement, an exception to a central paradigm of B cell immunity. J Exp Med 181:109-119
4. Anderson MK, Strong SJ, Litman RT, Luer CA, Amemiya CT, Rast JP, Litman GW (1999) A long form of the IgX gene in the skate exhibits a striking resemblance to the novel IgW and IgNARC genes in the shark. Immunogenetics 49:56-67
5. Bernstein RM, Schluter SF, Shen S, Marchalonis JJ (1996) A new high molecular weight immunoglobulin class from the carcharhine shark: implications for the properties of the primordial immunoglobulin. Proc Natl Acad Sci USA 93:3289-3293
6. Buck L, Axel R (1991) A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65:175-197
7. Diaz M, Greenberg AS, Flajnik MF (1998) Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: possible role in antigen-driven reactions in the absence of germinal centers. Proc Natl Acad Sci USA 95:14343-14348
8. Dreyfus DM (1992) Evidence suggesting an evolutionary relationship between transposable elements and immune system recombination sequences. Mol Immunol 29:807-810
9. Ghaffari SH, Lobb CJ (1999) Structure and genomic organization of a second cluster of immunoglobulin heavy chain gene segments in the channel catfish. J Immunol 162:1519-1529