Molecular and clinical features of non-Burkitt's, diffuse large-cell lymphoma of B-cell type associated with the e-MYC/immunoglobulin heavy-chain fusion gene

Journal of Clinical Oncology

Volumn 18, Issue 3, 2000, Pages 510-518

  Akasaka, Takashi ^a   Akasaka, Hiroshi ^a   Ueda, Chiyoko ^a   Yonetani, Noboru ^a   Maesako, Yoshitomo ^a   Shimizu, Akira ^a   Yamabe, Hirohiko ^a   Fukuhara, Shirou ^a   Uchiyama, Takashi ^a   Ohno, Hitoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; DNA; DOXORUBICIN; IMMUNOGLOBULIN HEAVY CHAIN; LACTATE DEHYDROGENASE; MYC PROTEIN; PROTEIN BCL 2; PROTEIN BCL 6; PROTEIN P53;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; B CELL LYMPHOMA; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL FEATURE; FEMALE; FUSION GENE; GENE AMPLIFICATION; GENE DELETION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN GENE; LARGE CELL LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MOLECULAR BIOLOGY; ONCOGENE C MYC; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SURVIVAL RATE;

EID: 0033950564     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.2000.18.3.510     Document Type: Article

References (51)

1. Magrath IT, Jain V, Jaffe ES: Small noncleaved cell lymphoma, in Knowles DM (ed): Neoplastic Hematopathology. Baltimore, MD, Williams & Wilkins, 1992, pp 749-772
2. Neri A, Barriga F, Knowles DM, et al: Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma. Proc Natl Acad Sci U S A 85:2748-2752, 1988
3. Pelicci P-G, Knowles DM II, Magrath I, et al: Chromosomal breakpoints and structural alterations of the c-myc locus differ in endemic and sporadic forms of Burkitt lymphoma. Proc Natl Acad Sci U S A 83:2984-2988, 1986
4. Harris NL, Jaffe ES, Stein H, et al: A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group. Blood 84:1361-1392, 1994
5. Macpherson N, Lesack D, Klasa R, et al: Small noncleaved, non-Burkitt's (Burkitt-like) lymphoma: Cytogenetics predict outcome and reflect clinical presentation. J Clin Oncol 17:1558-1567, 1999
6. The Non-Hodgkin's Lymphoma Classification Project: A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. Blood 89:3908-3918, 1997
7. Offit K, Wong G, Filippa DA, et al: Cytogenetic analysis of 434 consecutively ascertained specimens of non-Hodgkin's lymphoma: Clinical correlations. Blood 77:1508-1515, 1991
8. Yunis JJ, Mayer MG, Arnesen MA, et al: bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma. N Engl J Med 320:1047-1054, 1989
9. Kramer MHH, Hermans J, Wijburg E, et al: Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma. Blood 92:3152-3162, 1998
10. Levine EG, Arthur DC, Frizzera G, et al: Cytogenetic abnormalities predict clinical outcome in non-Hodgkin lymphoma. Ann Int Med 108:14-20, 1988
11. Ladanyi M, Offit K, Jhanwar SC, et al: MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas. Blood 77:1057-1063, 1991
12. Akasaka T, Muramatsu M, Ohno H, et al: Application of long-distance polymerase chain reaction to detection of junctional sequences created by chromosomal translocation in mature B-cell neoplasms. Blood 88:985-994, 1996
13. Akasaka T, Akasaka H, Ohno H: Polymerase chain reaction amplification of long DNA targets: Applications to analysis of chromosomal translocations in human B-cell tumors (review). Int J Oncol 12:113-121, 1998
14. The Non-Hodgkin's Lymphoma Pathologic Classification Project: National Cancer Institute sponsored study of classification of non-Hodgkin's lymphomas: Summary and description of a working formulation for clinical usage. Cancer 49:2112-2135, 1982
15. Deweindt C, Kerckaert JP, Tilly H, et al: Cloning of a breakpoint cluster region at band 3q27 involved in human non-Hodgkin's lymphoma. Genes Chromosomes Cancer 8:149-154, 1993
16. Tsujimoto Y, Finger LR, Yunis JJ, et al: Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 226:1097-1099, 1984
17. Cleary ML, Galili N, Sklar J: Detection of a second t(14;18) breakpoint cluster region in human follicular lymphomas. J Exp Med 164:315-320, 1986
18. Tsujimito Y, Bashir MM, Givol I, et al: DNA rearrangements in human follicular lymphoma can involve the 5′ or the 3′ region of the bcl-2 gene. Proc Natl Acad Sci U S A 84:1329-1331, 1987
19. Akasaka T, Akasaka H, Yonetani N, et al: Refinement of the BCL2/immunoglobulin heavy chain fusion gene in t(14;18)(q32;q21) by polymerase chain reaction amplification for long targets. Genes Chromosomes Cancer 21:17-29, 1998
20. Frank D, Cesarman E, Liu YF, et al: Posttransplantation lymphoproliferative disorders frequently contain type A not type B Epstein-Barr virus. Blood 85:1396-1403, 1995
21. Akasaka T, Muramatsu M, Kadowaki N, et al: p53 mutation in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with chromosomal translocations. Jpn J Cancer Res 87:930-937, 1996
22. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
23. Peto R, Pike MC, Armitage P, et al: Design and analysis of randomized clinical trials requiring prolonged observation of each patient: II. Analysis and examples. Br J Cancer 35:1-39, 1977
24. Hayday AC, Gillies SD, Saito H, et al: Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus. Nature 307:334-340, 1984
25. Ohno H, Furukawa T, Fukuhara S, et al: Molecular analysis of a chromosomal translocation, t(9;14)(p13;q32), in a diffuse large-cell lymphoma cell line expressing the Ki-1 antigen. Proc Natl Acad Sci U S A 87:628-632, 1990
26. Thangavelu M, Olopade O, Beckman E, et al: Clinical, morphologic and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11). Genes Chromosomes Cancer 2:147-158, 1990
27. Yonetani N, Akasaka T, Akasaka H, et al: Molecular features of a new human lymphoma cell line carrying both BCL2 and BCL6 gene rearrangements. Oncogene 17:971-979, 1998
28. Gaidano G, Ballerini P, Gong JZ, et al: p53 mutations in human lymphoid malignancies: Association with Burkitt lymphoma and chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 88:5413-5417, 1991
29. Akasaka T, Yonetani N, Akasaka H, et al: Detection of t(8; 14)(q24;q32) by polymerase chain reaction for long DNA targets: A report of two patients with B-cell non-Hodgkin's lymphoma. Int J Hematol 67:75-79, 1998
30. Offit K, Coco FL, Louie DC, et al: Rearrangement of the bcl-6 gene as a prognostic marker in diffuse large-cell lymphoma. N Engl J Med 331:74-80, 1994
31. Schouten HC, Sanger WG, Weisenburger DD, et al: Chromosomal abnormalities in untreated patients with non-Hodgkin's lymphoma: Associations with histology, clinical characteristics, and treatment outcome. Blood 75:1841-1847, 1990
32. Cabanillas F, Pathak S, Grant G, et al: Refractoriness to chemotherapy and poor survival related to abnormalities of chromosome 17 and 7 in lymphoma. Am J Med 87:167-172, 1989
33. Kristoffersson U, Heim S, Mandanl N, et al: Prognostic implication of cytogenetic findings in 106 patients with non-Hodgkin lymphoma. Cancer Genet Cytogenet 25:55-64, 1987
34. Fukuhara S, Nasu K, Kita K, et al: Cytogenetic approaches to the clarification of pathogenesis in lymphoid malignancies: Clinico-pathologic characterization of 14q+ marker-positive non-T-cell malignancies. Jpn J Clin Oncol 13:461-476, 1983
35. Ladanyi M, Offit K, Parsa NZ, et al: Follicular lymphoma with t(8;14)(q24;q32): A distinct clinical and molecular subset of t(8;14)-bearing lymphomas. Blood 79:2124-2130, 1992
36. Doria G, Frasca D: Genes, immunity, and senescence: Looking for a link. Immunol Rev 160:159-170, 1997
37. Kawanishi H, Joseph K: Effects of phorbol myristate and ionomycin on in vitro growth of aged Payer's patch T and B cells. Mech Ageing Dev 65:289-300, 1992
38. Ott G, Katzenberger T, Greiner A, et al: The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associated lymphoid (MALT-) type. Cancer Res 57:3944-3948, 1997
39. van Krieken JHJM, Raffeld M, Raghoebier S, et al: Molecular genetics of gastrointestinal non-Hodgkin's lymphomas: Unusual prevalence and pattern of c-myc rearrangements in aggressive lymphomas. Blood 76:797-800, 1990
40. van Krieken JHJM, Medeiros LJ, Pals ST, et al: Diffuse aggressive B-cell lymphomas of the gastrointestinal tract. Am J Clin Pathol 97:170-178, 1992
41. Rabbitts TH: Chromosomal translocations in human cancer. Nature 372:143-149, 1994
42. Yano T, Sander CA, Clark HM, et al: Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma. Oncogene 8:2741-2748, 1993
43. Bhatia K, Huppi K, Splanger G, et al: Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas. Nat Genet 5:56-61, 1993
44. Bhatia K, Spangler G, Gaidano G, et al: Mutations in the coding region of c-myc occur frequently in acquired immunodeficiency syndrome-associated lymphomas. Blood 84:883-888, 1994
45. Marin MC, Hsu B, Stephens LC, et al: The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivo. Exp Cell Res 217:240-247, 1995
46. Schmidt EV: MYC family ties. Nat Genet 14:8-10, 1996
47. Gu W, Bhatia K, Magrath IT, et al: Binding and suppression of the Myc transcriptional activation domain by p107. Science 264:251-254, 1994
48. Albagli O, Dhordain P, Bernardin F, et al: Multiple domains participate in distance-independent LAZ/BCL6-mediated transcriptional repression. Biochem Biophys Res Commun 220:911-915, 1996
49. Ye BH, Cattoretti G, Shen Q, et al: The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet 16:161-170, 1997
50. Magrath I, Adde M, Shad A, et al: Adults and children with small non-cleaved-cell lymphoma have a similar excellent outcome when treated with the same chemotherapy regimen. J Clin Oncol 14:925-934, 1996
51. Todeschini G, Tecchio C, Degani D, et al: Eighty-one percent event-free survival in advanced Burkitt's lymphoma/leukemia: No differences in outcome between pediatric and adult patients treated with the same intensive pediatric protocol. Ann Oncol 8:S77-S81, 1997 (suppl 1)