Polymer-supported silyl cyanide and silyl azide: Useful reagents for solid-phase applications

Biotechnology and Bioengineering

Volumn 71, Issue 1, 2000, Pages 38-43

  Missio, Andrea ^a,c   Marchioro, Carla ^a   Rossi, Tino ^a   Panunzio, Mauro ^b   Selva, Simona ^b   Seneci, Pierfausto ^a  

^a GSK   (Italy)

^b CNR   (Italy)

^c Research Pharmaceuticals: Chemistry   (Austria)

Author keywords

Polymer supported cyanohydrins; Polymer supported silyl azide; Polymer supported silyl cyanide

Indexed keywords

ALDEHYDES; CYANIDES; ESTERS; KETONES; SILICON COMPOUNDS;

CYANOHYDRINS; SILYL AZIDE; SILYL CYANIDE; TRIALKYLSILANES;

SYNTHESIS (CHEMICAL);

ALDEHYDE; AZIDE; CYANIDE; CYANOHYDRIN; KETONE; POLYMER; POLYSTYRENE; REAGENT; SILANE DERIVATIVE;

ARTICLE; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID STATE; SYNTHESIS;

ALDEHYDES; AZIDES; CYANIDES; INDICATORS AND REAGENTS; KETONES; MOLECULAR STRUCTURE; NITRILES; POLYMERS; SPECTROMETRY, MASS, SECONDARY ION;

EID: 0033949964     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(200024)71:1<38::AID-BIT6>3.0.CO;2-B     Document Type: Article

References (16)

1. Novel Bioactive Compounds Conference, Zurich, CH, October 1998.
2. Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gordon, E. M. J Med Chem 1994, 37, 1233-1251.
3. Gordon, E. M.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gallop, M. A. J Med Chem 1994, 37, 1385-1401.
4. Drewry, D. H.; Coe, D. M.; Poon, S. Med Res Rev 1998, 19, 97-148.
5. Hu, Y.; Porco, J. A. Jr.; Labadie, J. W.; Gooding, O. W.; Trost, B. M. J Org Chem 1998, 63, 4518.
6. Still, W. C.; Kahn, M.; Mitra, A. J. J Org Chem 1978, 43, 2923.
7. Harwood, L. M. Aldrichimica Acta 1985, 18, 25.
8. Hu, Y.; Porco, J. A., Jr. Tetrahedron Lett 1998, 39, 2711-2714.
9. Ruhlmann, K.; Reiche, A.; Becker, M. Chem Ber 1965, 98, 1814.
10. Scialdone, M. A.; Shuey, S. W.; Soper, P.; Hamuro, Y.; Burns, D. M. J Org Chem 1998, 63, 4802.
11. Evans, D. A.; Truesdale, L. K.; Carroll, G. L. J Chem Soc Chem Commun 1973, 55-56.
12. Evans, D. A.; Carroll, G. L.; Truesdale, L. K. J Org Chem 1974, 39, 914-917.
13. Deuchert, K.; Hertentein, U.; Hunig, S. Synthesis 1973, 777-779.
14. Saravanan, P.; Anand, R. V.; Singh, V. K. Tetrahedron Lett 1998, 39, 3823-3824.
15. Fitch, W. L.; Detre, G.; Holmes, C. P.; Shoolery, J. N.; Keifer, P. A. J Org Chem 1994, 59, 7955-7956.
16. Look, G. C.; Holmes, C. P.; Chinn, J. P.; Gallop, M. A. J Org Chem 1994, 59, 7588-7590.