Assessment of the percutaneous absorption of trichloroethylene in rats and humans using MS/MS real-time breath analysis and physiologically based pharmacokinetic modeling

Toxicological Sciences

Volumn 56, Issue 1, 2000, Pages 61-72

  Poet, Torka S ^a   Corley, Richard A ^a   Thrall, Karla D ^a   Edwards, Jeffrey A ^a   Tanojo, Hanafi ^b   Weitz, Karl K ^a   Hui, Xiaoying ^b   Maibach, Howard I ^b   Wester, Ronald C ^b  

^a BATTELLE MEMORIAL INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

PBPK modeling; Percutaneous absorption; Permeability coefficient; Realtime breath analysis

Indexed keywords

TRICHLOROETHYLENE;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; BIOLOGICAL MODEL; BREATH ANALYSIS; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NONHUMAN; NORMAL HUMAN; PARTITION COEFFICIENT; PREDICTION; RAT; RISK ASSESSMENT; SKIN ABSORPTION; SKIN PERMEABILITY; SOIL POLLUTION; SPECIES DIFFERENCE; TOXICOKINETICS; VALIDATION PROCESS; VOLATILIZATION; WATER POLLUTION;

ANIMALIA;

EID: 0033948075     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/56.1.61     Document Type: Article

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