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Volumn 106, Issue 1 I, 2000, Pages 101-109

Comparison of inflammatory responses to genetically engineered hypoallergenic derivatives of the major birch pollen allergen Bet v 1 and to recombinant Bet v 1 wild type in skin chamber fluids collected from birch pollen-allergic patients

Author keywords

CD69; Eosinophil cationic protein; Eosinophils; Hyopallergenic derivatives; RBet v 1; Recombinant birch pollen allergens; Skin blister chambers

Indexed keywords

ALLERGEN; CHEMOKINE; CYTOKINE; EOSINOPHIL CATIONIC PROTEIN; HISTAMINE; POLLEN ANTIGEN;

EID: 0033942152     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2000.106924     Document Type: Article
Times cited : (40)

References (37)
  • 1
    • 0024309396 scopus 로고
    • IgE and IgG antibodies of patients with allergy to birch pollen as tools to define the allergen profile of Betula verrucosa
    • Jarolim E, Rumpold H, Endler AT, Ebner H, Breitenbach M, Schneider, et al. IgE and IgG antibodies of patients with allergy to birch pollen as tools to define the allergen profile of Betula verrucosa. Allergy 1989;44:385-95.
    • (1989) Allergy , vol.44 , pp. 385-395
    • Jarolim, E.1    Rumpold, H.2    Endler, A.T.3    Ebner, H.4    Breitenbach, M.5    Schneider6
  • 2
    • 0030933864 scopus 로고    scopus 로고
    • Different profiles in specific IgE to rBet v 1 and rBet v 2 in patients allergic to birch pollen from six countries
    • Elfman L, Svensson M, Lidholm J, Pauli G, Valenta R. Different profiles in specific IgE to rBet v 1 and rBet v 2 in patients allergic to birch pollen from six countries. Int Arch Allergy Immunol 1997;113:249-51.
    • (1997) Int Arch Allergy Immunol , vol.113 , pp. 249-251
    • Elfman, L.1    Svensson, M.2    Lidholm, J.3    Pauli, G.4    Valenta, R.5
  • 3
    • 0024443144 scopus 로고
    • The gene coding for the major birch pollen allergen, Bet v 1, is highly homologous to a pea diseases resistance response gene
    • Breiteneder H, Pettenburger K, Bito A, Valenta R, Kraft D, Rumpold H, et al. The gene coding for the major birch pollen allergen, Bet v 1, is highly homologous to a pea diseases resistance response gene. EMBO J 1989;8:1935-8.
    • (1989) EMBO J , vol.8 , pp. 1935-1938
    • Breiteneder, H.1    Pettenburger, K.2    Bito, A.3    Valenta, R.4    Kraft, D.5    Rumpold, H.6
  • 4
    • 0030937231 scopus 로고    scopus 로고
    • Conversion of the major birch pollen allergen, Bet v 1, into two non-anaphylactic T cell epitope-containing fragments: Candidates for a novel form of specific immunotherapy
    • Vrtala S, Hirtenlehner K, Vangelista L, Pastore A, Eichler HG, Sperr WR, et al. Conversion of the major birch pollen allergen, Bet v 1, into two non-anaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapy. J Clin Invest 1997;99:1673-81.
    • (1997) J Clin Invest , vol.99 , pp. 1673-1681
    • Vrtala, S.1    Hirtenlehner, K.2    Vangelista, L.3    Pastore, A.4    Eichler, H.G.5    Sperr, W.R.6
  • 5
    • 0032963493 scopus 로고    scopus 로고
    • Genetic engineering of recombinant hypoallergenic oligomers of the major pollen allergen, Bet v 1: Candidates for specific immunotherapy
    • Vrtala S, Hirtenlehner K, Susani M, Hufnagl P, Binder BR, Vangelista L, et al. Genetic engineering of recombinant hypoallergenic oligomers of the major pollen allergen, Bet v 1: candidates for specific immunotherapy. Int Arch Allergy Immunol 1999;118:218-9.
    • (1999) Int Arch Allergy Immunol , vol.118 , pp. 218-219
    • Vrtala, S.1    Hirtenlehner, K.2    Susani, M.3    Hufnagl, P.4    Binder, B.R.5    Vangelista, L.6
  • 6
    • 0032739068 scopus 로고    scopus 로고
    • Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: Results obtained with a mix of two recombinant Bet v 1 fragments and rBet v 1 trimer in a Swedish population before the birch pollen season
    • van Hage-Hamsten M, Kronqvist M, Zetterström O, Johansson E, Niederberger V, Vrtala S, et al. Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: results obtained with a mix of two recombinant Bet v 1 fragments and rBet v 1 trimer in a Swedish population before the birch pollen season. J Allergy Clin Immunol 1999;104:969-72.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 969-972
    • Van Hage-Hamsten, M.1    Kronqvist, M.2    Zetterström, O.3    Johansson, E.4    Niederberger, V.5    Vrtala, S.6
  • 7
    • 85031589678 scopus 로고    scopus 로고
    • Comparison of genetically engineered hypoallergenic rBet v 1 derivatives with rBet v 1 wildtype by skin prick and intradermal testing: Results obtained in a French population
    • In press
    • Pauli G, Purohit A, Oster J-P, De Blay F, Vrtala S, Niederberger V, et al. Comparison of genetically engineered hypoallergenic rBet v 1 derivatives with rBet v 1 wildtype by skin prick and intradermal testing: results obtained in a French population. Clin Exp Allergy. In press.
    • Clin Exp Allergy
    • Pauli, G.1    Purohit, A.2    Oster, J.-P.3    De Blay, F.4    Vrtala, S.5    Niederberger, V.6
  • 8
    • 0027930218 scopus 로고
    • Eosinophils in the 1990s: New perspectives on their role in health and disease
    • Wardlaw AJ. Eosinophils in the 1990s: new perspectives on their role in health and disease. Postgrad Med J 1994;70:536-52.
    • (1994) Postgrad Med J , vol.70 , pp. 536-552
    • Wardlaw, A.J.1
  • 10
    • 0027231657 scopus 로고
    • Cellular and biochemival analysis of induced sputum from asthmatic and from healthy subjects
    • Fahy JV, Liu J, Wong H, Boushey HA. Cellular and biochemival analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993;147:1126-31.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 1126-1131
    • Fahy, J.V.1    Liu, J.2    Wong, H.3    Boushey, H.A.4
  • 12
    • 0027507513 scopus 로고
    • CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines
    • Hartnell A, Robinson DS, Kay AB, Wardlaw AJ. CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines. Immunology 1993;80:281-6.
    • (1993) Immunology , vol.80 , pp. 281-286
    • Hartnell, A.1    Robinson, D.S.2    Kay, A.B.3    Wardlaw, A.J.4
  • 13
    • 0026736706 scopus 로고
    • In vivo expression on lung eosinophils in eosinophilic pneumonia: CD69 as a possible activation marker for eosinophils
    • Nishikawa K, Morii T, Ako H, Hamada K, Saito S, Narita N. In vivo expression on lung eosinophils in eosinophilic pneumonia: CD69 as a possible activation marker for eosinophils. J Allergy Clin Immunol 1992;90:169-74.
    • (1992) J Allergy Clin Immunol , vol.90 , pp. 169-174
    • Nishikawa, K.1    Morii, T.2    Ako, H.3    Hamada, K.4    Saito, S.5    Narita, N.6
  • 14
    • 0029885142 scopus 로고    scopus 로고
    • Anti-IgE-induced accumulation of leukocytes, mediators, and albumin in skin chamber fluid from healthy and atopic subjects
    • Raud J, Halldén G, Roquet A, van Hage-Hamsten M, Alkner U, Hed J, et al. Anti-IgE-induced accumulation of leukocytes, mediators, and albumin in skin chamber fluid from healthy and atopic subjects. J Allergy Clin Immunol 1996;97:1151-63.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 1151-1163
    • Raud, J.1    Halldén, G.2    Roquet, A.3    Van Hage-Hamsten, M.4    Alkner, U.5    Hed, J.6
  • 15
    • 0032734015 scopus 로고    scopus 로고
    • Characterisation of eosinophils and detection of eotaxin in skin chamber fluid after challenge with relevant allergen in patients with mild asthma
    • Fernvik E, Grönneberg R, Lundahl J, Raud J, Zetterström O, van Hage-Hamsten M, et al. Characterisation of eosinophils and detection of eotaxin in skin chamber fluid after challenge with relevant allergen in patients with mild asthma. Clin Exp Allergy 1999;29:1515-25.
    • (1999) Clin Exp Allergy , vol.29 , pp. 1515-1525
    • Fernvik, E.1    Grönneberg, R.2    Lundahl, J.3    Raud, J.4    Zetterström, O.5    Van Hage-Hamsten, M.6
  • 17
    • 0024435624 scopus 로고
    • A new membrane permeabilization method for the detection of intracellular antigens by flow cytometry
    • Halldén G, Andersson U, Hed J, Johansson SGO. A new membrane permeabilization method for the detection of intracellular antigens by flow cytometry. J Immunol Meth 1989;124:103-9.
    • (1989) J Immunol Meth , vol.124 , pp. 103-109
    • Halldén, G.1    Andersson, U.2    Hed, J.3    Johansson, S.G.O.4
  • 18
    • 0027731105 scopus 로고
    • Counts of activated blood eosinophils for monitoring asthma
    • Hed J, Halldén G. Counts of activated blood eosinophils for monitoring asthma. Allergy 1993;48:1787-93.
    • (1993) Allergy , vol.48 , pp. 1787-1793
    • Hed, J.1    Halldén, G.2
  • 19
    • 0032982263 scopus 로고    scopus 로고
    • Allergen induced accumulation of eosinophils and lymphocytes in skin chambers is associated with increased levels of IL-4 and sVCAM-1
    • Fernvik E, Halldén G, Lundahl J, Raud J, Alkner U, van Hage-Hamsten M, et al. Allergen induced accumulation of eosinophils and lymphocytes in skin chambers is associated with increased levels of IL-4 and sVCAM-1. Allergy 1999;54:455-63.
    • (1999) Allergy , vol.54 , pp. 455-463
    • Fernvik, E.1    Halldén, G.2    Lundahl, J.3    Raud, J.4    Alkner, U.5    Van Hage-Hamsten, M.6
  • 20
    • 0033195032 scopus 로고    scopus 로고
    • Eotaxin. An essential mediator of eosinophil trafficking into mucosal tissue
    • Rothenberg ME. Eotaxin. An essential mediator of eosinophil trafficking into mucosal tissue. Am J Respir Cell Mol Biol 1999;21:291-5.
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 291-295
    • Rothenberg, M.E.1
  • 21
    • 0021367563 scopus 로고
    • Monoclonal antibodies distinguish between storage and secreted forms of eosinophil cationic protein
    • Tai PC, Spry CJF, Peterson C, Venge P, Olsson I. Monoclonal antibodies distinguish between storage and secreted forms of eosinophil cationic protein. Nature 1984;309:182-4.
    • (1984) Nature , vol.309 , pp. 182-184
    • Tai, P.C.1    Spry, C.J.F.2    Peterson, C.3    Venge, P.4    Olsson, I.5
  • 22
    • 0032870091 scopus 로고    scopus 로고
    • Reactivity of monoclanal antibodies EG1 and EG2 with eosinophils and their granule proteins
    • Nakajima H, Loegering DA, Kita H, Kephart GM, Gleich GJ. Reactivity of monoclanal antibodies EG1 and EG2 with eosinophils and their granule proteins. J Leukoc Biol 1999;66:447-54.
    • (1999) J Leukoc Biol , vol.66 , pp. 447-454
    • Nakajima, H.1    Loegering, D.A.2    Kita, H.3    Kephart, G.M.4    Gleich, G.J.5
  • 23
    • 0029129339 scopus 로고
    • Eosinophil activity reflects clinical status in patients with asthma before and during a predisolone course
    • Skedinger M, Halldén G, Lundahl J, Hed J, Zetterström O. Eosinophil activity reflects clinical status in patients with asthma before and during a predisolone course. Ann Allergy Asthma Immunol 1995;75:250-5.
    • (1995) Ann Allergy Asthma Immunol , vol.75 , pp. 250-255
    • Skedinger, M.1    Halldén, G.2    Lundahl, J.3    Hed, J.4    Zetterström, O.5
  • 24
    • 0029809934 scopus 로고    scopus 로고
    • The degree of natural allergen exposure modifies eosinophil activity markers in the circulation of patients with mild asthma
    • Fernvik E, Grönneberg R, Lundahl J, Hed J, Andersson O, Johansson SGO, et al. The degree of natural allergen exposure modifies eosinophil activity markers in the circulation of patients with mild asthma. Allergy 1996;51:697-705.
    • (1996) Allergy , vol.51 , pp. 697-705
    • Fernvik, E.1    Grönneberg, R.2    Lundahl, J.3    Hed, J.4    Andersson, O.5    Johansson, S.G.O.6
  • 25
    • 0032754936 scopus 로고    scopus 로고
    • Conditions in blood sampling conditions that extend the ex vivo stability of eosinophil activity markers in peripheral blood from allergic patients and healthy controls
    • Halldén G, Nopp A, Ihre E, Peterson C, Lundahl J. Conditions in blood sampling conditions that extend the ex vivo stability of eosinophil activity markers in peripheral blood from allergic patients and healthy controls. Ann Allergy Asthma Immunol 1999;83:413-21.
    • (1999) Ann Allergy Asthma Immunol , vol.83 , pp. 413-421
    • Halldén, G.1    Nopp, A.2    Ihre, E.3    Peterson, C.4    Lundahl, J.5
  • 26
    • 0033982186 scopus 로고    scopus 로고
    • The impact of eotaxin- and IL5-induced adhesion and transmigration of eosinophil activity markers
    • Fernvik E, Lundahl J, Halldén G. The impact of eotaxin-and IL5-induced adhesion and transmigration of eosinophil activity markers. Inflammation 2000;1:73-87.
    • (2000) Inflammation , vol.1 , pp. 73-87
    • Fernvik, E.1    Lundahl, J.2    Halldén, G.3
  • 27
    • 0033963981 scopus 로고    scopus 로고
    • Quantitative, rather than qualitative, differences in CD69 upregulation in human blood eosinophils upon activation with selected stimuli
    • Nopp A, Lundahl J, Halldén G. Quantitative, rather than qualitative, differences in CD69 upregulation in human blood eosinophils upon activation with selected stimuli. Allergy 2000;55:148-56.
    • (2000) Allergy , vol.55 , pp. 148-156
    • Nopp, A.1    Lundahl, J.2    Halldén, G.3
  • 28
    • 0033010012 scopus 로고    scopus 로고
    • The effect of in vitro activation and platelet interaction on the CD9 distribution and adhesion properties of human eosinophils
    • Fernvik E, Lundahl J, Magnusson CGM, Halldén G. The effect of in vitro activation and platelet interaction on the CD9 distribution and adhesion properties of human eosinophils. Inflamm Res 1999;48:28-35.
    • (1999) Inflamm Res , vol.48 , pp. 28-35
    • Fernvik, E.1    Lundahl, J.2    Magnusson, C.G.M.3    Halldén, G.4
  • 29
    • 0025745450 scopus 로고
    • Granulocyte/machrophage colony-stimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils
    • Kita H, Ohnishi T, Okubo Y, Weiler D, Abrams JS, Gleich GJ. Granulocyte/machrophage colony-stimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils. J Exp Med 1991;174:745-8.
    • (1991) J Exp Med , vol.174 , pp. 745-748
    • Kita, H.1    Ohnishi, T.2    Okubo, Y.3    Weiler, D.4    Abrams, J.S.5    Gleich, G.J.6
  • 30
    • 0032777880 scopus 로고    scopus 로고
    • Cytokines in asthma
    • Chung KF, Barnes PJ. Cytokines in asthma. Thorax 1999;54:825-57.
    • (1999) Thorax , vol.54 , pp. 825-857
    • Chung, K.F.1    Barnes, P.J.2
  • 31
    • 0028850516 scopus 로고
    • Identification of messenger RNA for IL-4 in human eosinophils with granule localization and release of the translated product
    • Moqbel R, Ying S, Barkans J, Newman TM, Kimmitt P, Wakelin M, et al. Identification of messenger RNA for IL-4 in human eosinophils with granule localization and release of the translated product. J Immunol 1995;155:4939-47.
    • (1995) J Immunol , vol.155 , pp. 4939-4947
    • Moqbel, R.1    Ying, S.2    Barkans, J.3    Newman, T.M.4    Kimmitt, P.5    Wakelin, M.6
  • 32
    • 0029047108 scopus 로고
    • Expression of interleukin-4 and interleukin-5 mRNA in developing cutaneous late phase reactions
    • Vowels BR, Rook AH, Cassin M, Zweiman B. Expression of interleukin-4 and interleukin-5 mRNA in developing cutaneous late phase reactions. J Allergy Clin Immunol 1995;96:92-6.
    • (1995) J Allergy Clin Immunol , vol.96 , pp. 92-96
    • Vowels, B.R.1    Rook, A.H.2    Cassin, M.3    Zweiman, B.4
  • 33
    • 0030853853 scopus 로고    scopus 로고
    • Cytokine levels and inflammatory responses in developing late-phase reactions in the skin
    • Zweiman B, Kaplan AP, Tong L, Moskovitz BS. Cytokine levels and inflammatory responses in developing late-phase reactions in the skin. J Allergy Clin Immunol 1997;100:104-9.
    • (1997) J Allergy Clin Immunol , vol.100 , pp. 104-109
    • Zweiman, B.1    Kaplan, A.P.2    Tong, L.3    Moskovitz, B.S.4
  • 35
    • 0025980415 scopus 로고
    • Prednisone inhibits the appearance of inflammatory mediators and the influx of eosinophils and basophils associated with the cutaneous late-phase response to allergen
    • Charlesworth EN, Kagney-Sobotka A, Schleimer RP, Norman PS, Lichtenstein LM. Prednisone inhibits the appearance of inflammatory mediators and the influx of eosinophils and basophils associated with the cutaneous late-phase response to allergen. J Immunol 1991;146:671-6.
    • (1991) J Immunol , vol.146 , pp. 671-676
    • Charlesworth, E.N.1    Kagney-Sobotka, A.2    Schleimer, R.P.3    Norman, P.S.4    Lichtenstein, L.M.5
  • 36
    • 0033214919 scopus 로고    scopus 로고
    • C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: Association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 34-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (monocyte chemoattractant protein-3 and RANTES)
    • Ying S, Robinson DS, Meng Q, Barata LT, McEuen AR, Buckley MG, et al. C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 34-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (monocyte chemoattractant protein-3 and RANTES). J Immunol 1999;163:3976-84.
    • (1999) J Immunol , vol.163 , pp. 3976-3984
    • Ying, S.1    Robinson, D.S.2    Meng, Q.3    Barata, L.T.4    McEuen, A.R.5    Buckley, M.G.6
  • 37
    • 0029619450 scopus 로고
    • Chronologic analysis of in situ cytokine expression in mite allergen-induced dermatitis in atopic subjects
    • Yamada N, Wakugawa M, Kuwata S, Yoshida T, Nakagawa H. Chronologic analysis of in situ cytokine expression in mite allergen-induced dermatitis in atopic subjects. J Allergy Clin Immunol 1995;96:1069-75.
    • (1995) J Allergy Clin Immunol , vol.96 , pp. 1069-1075
    • Yamada, N.1    Wakugawa, M.2    Kuwata, S.3    Yoshida, T.4    Nakagawa, H.5


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