Cysteine protease production by human osteosarcoma cells (MG63, SaOS2) and its modulation by soluble factors

Cytokine

Volumn 12, Issue 5, 2000, Pages 539-542

  Damiens, Christelle ^a   Grimaud, Eva ^a   Rousselle, Anne Valeérie ^a   Charrier, Ceéline ^a   Fortun, Yannick ^a   Heymann, Dominique ^a   Padrines, Marc ^a  

^a Universite de Nantes   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN L; COLLAGEN TYPE 1; CYSTEINE PROTEINASE; GROWTH HORMONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; ONCOSTATIN M; SOMATOMEDIN C;

ARTICLE; BONE REMODELING; CANCER CELL CULTURE; COLLAGEN DEGRADATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; OSSIFICATION; OSTEOLYSIS; OSTEOSARCOMA CELL; PRIORITY JOURNAL;

EID: 0033939293     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1999.0593     Document Type: Article

References (15)

1. Rodan GA, Rodan SB. The cells of bone. Riggs BL, Melton LJ. Osteoporosis: Etiology, Diagnosis and Management. 1995;1-39 Lippincott-Raven, Philadelphia.
2. Barnard R, Ng KW, Martin TJ, Waters MJ. Growth hormone (GH) receptors in clonal osteoblast-like cells mediate a mitogenic response to GH. Endocrinology. 128:1991;1459-1464.
3. Delany AM, Pash JM, Canalis E. Cellular and clinical perspectives on skeletal insulin-like growth factor I. J Cell Biochem. 55:1994;328-333.
4. Jay PR, Centrella M, Lorenzo J, Bruce AG, Horowitz MC. Oncostatin-M: a new bone active cytokine that activates osteoblasts and inhibits bone resorption. Endocrinology. 137:1996;1151-1158.
5. Cornish J, Callon K, King A, Edgar S, Reid IR. The effect of leukemia inhibitory factor on bone in vivo. Endocrinology. 132:1993;1359-1366.
6. Van Beek E, Van Der Wee-Pals L, Van de Ruit M, Nijweide P, Papopoulos S, Löwik C. Leukemia inhibitory factor inhibits osteoclastic resorption, growth, mineralization, and alkaline phosphatase activity in fetal mouse metacarpal bones in culture. J Bone Miner Res. 8:1993;191-198.
7. Greenfield EM, Horowitz MC, Lavish SA. Stimulation by parathyroid hormone of interleukin-6 and leukemia inhibitory factor expression in osteoblasts is an immediate-early gene response induced by cAMP signal transduction. J Biol Chem. 271:1996;10984-10989.
8. Aisa MC, Rahman S, Senin U, Maggio D, Russell RGG. Cathepsin B activity in normal human osteoblast-like cells and human osteoblastic osteosarcoma cells (MG63): regulation by interleukin-1β and parathyroid hormone. Biochim Biophys Acta. 1290:1996;29-36.
9. Park I, Lee S, Jeon D, Lee J, Hawng C, Hawng B, Lee S, Hong W, Hong S. Enhanced expression of cathepsin L in metastatic bone tumors. J Korean Med Sci. 11:1996;144-148.
10. Lah TT, Kos J. Cysteine proteinases in cancer progression and their clinical relevance for prognosis. Biol Chem. 379:1998;125-130.
11. Barton BE. IL-6: Insights into Novel Biological Activities. Clin Immunol Immunopathol. 85:1997;16-20.
12. Heymann D, Godard A, Raher S, Bentouimou N, Blanchard F, Cherel M, Hallet MM, Jacques Y. Leukemia inhibitory factor (LIF) and oncostatin M (OSM) high affinity binding require additional receptor subunits besides gp130 and gp190. Cytokine. 8:1996;197-205.
13. Bellido T, Borba VZC, Roberson P, Manolagas SC. Activation of the janus kinase/STAT (signal transducer and activator of transcription) signal transduction. Pathway by interleukin-6-type cytokines promotes osteoblast differentiation. Endocrinology. 138:1997;3666-3676.
14. Okasaki R, Conover CA, Harris SA, Spelsberg T, Riggs KBL. Normal human osteoblast-like cells consistently express genes for insulin-like growth factors I and II but transformed human osteoblast cell lines do not. J Bone Miner Res. 10:1995;788-795.
15. Buck MR, Karustis DG, Day NA, Honn KV, Sloane BF. Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumor tissues. Biochem J. 282:1992;273-278.