Acute hypoxic pulmonary vascular response does not accompany plasma endothelin-1 elevation in subjects susceptible to high altitude pulmonary edema

Internal Medicine

Volumn 35, Issue 4, 1996, Pages 257-260

  Droma, Yunden ^a   Ri Li, Ge ^a   Tanaka, Masao ^a   Koizumi, Tomonobu ^a   Hanaoka, Masayuki ^a   Miyahara, Takashige ^a   Yamaguchi, Shinji ^a   Okada, Kazuyoshi ^a   Yoshikawa, Sawako ^a   Fujimoto, Keisaku ^a   Matsuzawa, Yukinori ^a   Kubo, Keishi ^a   Kobayashi, Toshio ^a   Sekiguchi, Morie ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Doppler echocardiography; High altitude pulmonary edema (HAPE); Hypoxia; Pulmonary hypertension

Indexed keywords

ENDOTHELIN 1;

ACUTE DISEASE; ADULT; ALTITUDE DISEASE; ANOXIA; ARTICLE; BLOOD; CASE CONTROL STUDY; FEMALE; HUMAN; LUNG CIRCULATION; LUNG EDEMA; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION;

ACUTE DISEASE; ADULT; ALTITUDE SICKNESS; ANOXIA; CASE-CONTROL STUDIES; ENDOTHELIN-1; FEMALE; HUMANS; MALE; MIDDLE AGED; PULMONARY CIRCULATION; PULMONARY EDEMA;

EID: 0030122146     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.35.257     Document Type: Article

References (14)

1. Kawashima A, Kubo K, Kobayashi T, Sekiguchi M. Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema. J Appl Physiol 67: 1982, 1989.
2. Allen SW, Chatfield BA, Koppenhafer SL, et al. Circulating immunoreactive endothelin-1 (irET-1) and hypoxic pulmonary vasoconstriction in childhood pulmonary hypertension. Pediatr Res 31: 16A, 1992.
3. Shirakami G, Nakao K, Saito Y, et al. Acute pulmonary alveolar hypoxia increases lung and plasma endothelin-1 levels in conscious rats. Life Sci 48:969, 1991.
4. Vanhoutte PM, Auch-Schwelk W, Boulanger C, et al. Does endothetin-1 mediate endothelium-dependent contractions during anoxia? J Cardiovasc Pharmacol 13 Suppl 5: S124, 1989.
5. Yagi H, Yamada H, Kobayashi T, Sekiguchi M. Doppler assessment of pulmonary hypertension induced by hypoxic breathing in subjects susceptible to high altitude pulmonary edema. Am Rev Respir Dis 142:76, 1990.
6. Hultgren HN, Marticorena EA. High altitude pulmonary edema. Epidemiologic observation in Peru. Chest 74: 372, 1978.
7. Kitabatake A, Inoue M, Asao M, et al. Noninvasive evaluation of pulmonary hypertension by a pulsed Doppler technique. Circulation 68: 302, 1983.
8. Currie PJ, Seward JB, Chan KL, et al. Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler-cathetenzation study in 127 patients. J Am Coll Cardiol 6: 750, 1985.
9. Ando K, Hirata Y, Shichiri M, Emort T, Marumo F. Presence of immunoreactive endothelin in human plasma. FEBS Lett 245: 164, 1989.
10. Tramarin R, Torbicki A, Marchandise B, Laaban JP, Morpurgo M. Doppler echocardiographic evaluation of pulmonary artery pressure in chronic obstructive pulmonary disease. A European multicentre study. Working Group on Noninvasive Evaluation of Pulmonary Artery Pressure. European Office of the World Health Organization, Copenhagen. Eur Heart J 12: 103, 1991.
11. Chan KL, Currie PJ, Seward JB, Hagler DJ, Mair DD, Tajik AJ. Comparison of three Doppler ultrasound methods in the prediction of pulmonary artery pressure. J Am Coll Cardiol 9: 549, 1987.
12. Douglas SA, Vickery-Clark LM, Ohlstein EH, et al. Endothelin-1 does not mediate hypoxic vasoconstriction in canine isolated blood vessels: effect of BQ-123. Br J Pharmacol 108: 418, 1993.
13. Wong J, Vanderford PA, Winters JW, Chang R, Soifer SJ, Fineman JR. Endothelin-1 dose not mediate acute hypoxic pulmonary vasoconstriction in the intact newborn lamb. J Cardiovasc Pharmacol 22 Suppl 8 S262, 1993.
14. Li H, Chen SJ, Chen YF, et al. Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia. J Appl Physiol 77: 1451, 1994.