Further evidence for corticomotor hyperexcitability in amyotrophic lateral sclerosis

Muscle and Nerve

Volumn 23, Issue 7, 2000, Pages 1044-1050

  Naka, Daisuke ^a,b   Mills, Kerry R ^a,c  

^a RADCLIFFE INFIRMARY   (United Kingdom)

^b NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

ALS; Collision experiment; Hyperexcitability; Magnetic stimulation

Indexed keywords

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERACTIVITY; MALE; MOTOR CORTEX; MUSCLE ACTION POTENTIAL; NORMAL HUMAN; PRIORITY JOURNAL; SPINAL CORD MOTONEURON; STIMULUS RESPONSE; TRANSCRANIAL MAGNETIC STIMULATION;

ACTION POTENTIALS; ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; CEREBRAL CORTEX; ELECTRIC STIMULATION; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR NEURONS; MUSCLE, SKELETAL; REFLEX;

EID: 0033935841     PISSN: 0148639X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4598(200007)23:7<1044::AID-MUS6>3.0.CO;2-Q     Document Type: Article

References (24)

1. Awiszus F, Feistner H. Comparison of single motor unit responses to transcranial magnetic and peroneal nerve stimulation in the tibialis anterior muscle of patients with amyotrophic lateral sclerosis. Electroencephalogr Clin Neurophysiol 1995;97:90-95.
2. Brooks BR. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. J Neurol Sci 1994;124:96-107.
3. Burke D, Grades JM, Mazevet D, Meunier S, Pierrot Deseilligny E. Non-monosynaptic transmission of the cortical command for voluntary movement in man. J Physiol (Lond) 1994; 480:191-202.
4. Caramia MD, Cicinelli P, Paradiso C, Mariorenzi R, Zarola F, Bernardi G, Rossini PM. Excitability changes of muscular responses to magnetic brain stimulation in patients with central motor disorders. Electroencephalogr Clin Neurophysiol 1991;81:243-250.
5. Day BL, Rothwell JC, Thompson PD, Dick JP, Cowan JM, Berardelli A, Marsden CD. Motor cortex stimulation in intact man. 2. Multiple descending volleys. Brain 1987;110: 1191-1209.
6. Desiato MT, Caramia MD. Towards a neurophysiological marker of amyotrophic lateral sclerosis as revealed by changes in cortical excitability. Electroencephalogr Clin Neurophysiol 1997;105:1-7.
7. Di Lazzaro V, Restuccia D, Oliviero A, Profice L, Insola A, Mazzone P, Tonali P, Rothwell J. Effects of voluntary contraction on descending volleys by transcranial stimulation in conscious humans. J Physiol (Lond) 1998;508:625-633.
8. Eisen A, Entezari Taher M, Stewart H. Cortical projections to spinal motoneurons: changes with aging and amyotrophic lateral sclerosis. Neurology 1996;46:1396-1404.
9. Eisen A, Pant B, Stewart H. Cortical excitability in amyotrophic lateral sclerosis: a clue to pathogenesis. Can J Neurol Sci 1993;20:11-16.
10. Enterzari Taher M, Eisen A, Stewart H, Nakajima M. Abnormalities of cortical inhibitory neurons in amyotrophic lateral sclerosis. Muscle Nerve 1997;20:65-71.
11. Gracies JM, Meunier S, Pierrot Deseilligny E. Evidence for corticospinal excitation of presumed propriospinal neurones in man. J Physiol (Lond) 1994;475:509-518.
12. Hess CW, Mills KR, Murray NM. Responses in small hand muscles from magnetic stimulation of the human brain. J Physiol (Lond) 1987;388:397-419.
13. Kohara N, Kaji R, Kojima Y, Mills KR, Fujii H, Hamano T, Kimura J, Takamatsu N, Uchiyama T. Abnormal excitability of the corticospinal pathway in patients with amyotrophic lateral sclerosis: a single motor unit study using transcranial magnetic stimulation. Electroencephalogr Clin Neurophysiol 1996;101:32-41.
14. Maier M, Illert M, Kirkwood P, Nielsen J, Lemon R. Does a C3-C4 propriospinal system transmit conicospinal excitation in the primate? An investigation in the macaque monkey. J Physiol (Lond) 1998:511:191-212.
15. Mazevet D, Pierrot Deseilligny E, Rothwell JC. A propriospinal-like contribution to electromyographic responses evoked in wrist extensor muscles by transcranial stimulation of the motor cortex in man. Exp Brain Res 1996;109:495-499.
16. Mazzocchio R, Rothwell JC, Rossi A. Distribution of Ia effects onto human hand muscle motoneurones as revealed using an H reflex technique. J Physiol (Lond) 1995;489:263-273.
17. Mills KR. Motor neuron disease. Studies of the corticospinal excitation of single motor neurons by magnetic brain stimulation. Brain 1995;118:971-982.
18. Mills KR, Boniface SJ, Schubert M. Magnetic brain stimulation with a double coil: the importance of coil orientation. Electroencephalogr Clin Neurophysiol 1992;85:17-21.
19. Mills KR, Nithi KA. Corticomotor threshold is reduced in early idiopathic amyotrophic lateral sclerosis. Muscle Nerve 1997;20:1137-1141.
20. Mills KR, Nithi KA. Corticomotor threshold to magnetic stimulation: normal values and repeatability. Muscle Nerve 1997;20:570-576.
21. Nakajima M, Eisen A, McCarthy R, Olney RK, Aminoff MJ. Reduced corticomotoneuronal excitatory postsynaptic potentials (EPSPs) with normal Ia afferent EPSPs in amyotrophic lateral sclerosis. Neurology 1996;47:1555-1561.
22. Pauvert V, Picrrot-Deseilligny E, Rothwell J. Role of spinal premotoneurones in mediating corticospinal input to forelimb motoneurones in man. J Physiol (Lond) 1998;508: 301-312.
23. Yokota T, Yoshino A, Inaba A, Saito Y. Double cortical stimulation in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 1996;61:596-600.
24. Ziemann U, Winter M, Reimers CD, Reimers K, Tergau F, Paulus W. Impaired motor cortex inhibition in patients with amyotrophic lateral sclerosis. Evidence from paired transcranial magnetic stimulation. Neurology 1997;49:1292-1298.