The Entamoeba histolytica mitochondrion-derived organelle (crypton) contains double-stranded DNA and appears to be bound by a double membrane

Infection and Immunity

Volumn 68, Issue 7, 2000, Pages 4319-4322

  Ghosh, Sudip ^a   Field, Jessica ^a   Rogers, Rick ^a   Hickman, Mark ^a   Samuelson, John ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA ANTIBODY; DOUBLE STRANDED DNA; FLUOROCHROME; HEAT SHOCK PROTEIN 60; MONOCLONAL ANTIBODY;

ARTICLE; CELL ORGANELLE; CONTROLLED STUDY; DNA BINDING; ENTAMOEBA HISTOLYTICA; INTRACELLULAR MEMBRANE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; DNA, PROTOZOAN; ENTAMOEBA HISTOLYTICA; INTRACELLULAR MEMBRANES; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MITOCHONDRIA; ORGANELLES;

EID: 0033932808     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.7.4319-4322.2000     Document Type: Article

References (32)

1. Akhmanova, A., F. Voncken, T. van Alen, A. van Hoek, B. Boxma, G. Vogels, M. Veenhuis, and J. H. Hackstein. 1998. A hydrogenosome with a genome. Nature 396:527-528.
2. Andersson, S. G. E., and C. G. Kurland. 1999. Origins of mitochondria and hydrogenosomes. Curr. Opin. Microhiol. 2:535-541.
3. Benchimol, M., P. J. Johnson, and W. Desouza. 1996. Morphogenesis of the hydrogenosome - an ultrastructural study. Biol. Cell 87:197-205.
4. Bradley, P. J., C. J. Lahti, E. Plumper, and P. J. Johnson. 1997. Targeting and translocation of proteins into the hydrogenosome of the protist Trichomonas: similarities with mitochondrial protein import. EMBO J. 16: 3484-3493.
5. Bui, E. T. N., P. J. Bradley, and P. J. Johnson. 1996. A common evolutionary origin for mitochondria and hydrogenosomes. Proc. Natl. Acad. Sci. USA 93:9651-9656.
6. Bui, E. T., and P. J. Johnson. 1996. Identification and characterization of [Fe]-hydrogenases in the hydrogenosome of Trichomonas vaginalis. Mol. Biochem. Parasitol. 76:305-310.
7. Cavalier-Smith, T. 1987. Eukaryotes with no mitochondria. Nature 326:332-333.
8. Clark, C. G., and A. J. Roger. 1995. Direct evidence for secondary loss of mitochondria in Entamoeba histolytica. Proc. Natl. Acad. Sci. USA 92:6518-6521.
9. Claros, M. G., and P. Vincens. 1996. Computational method to predict mitochondrially imported proteins and their targeting sequences. Eur. J. Biochem. 241:779-786.
10. Ghosh, S. K., J. Field, M. Frisardi, B. Rosenthal, Z. Mai, R. Rogers, and J. Samuelson. 1999. Chitinase secretion by encysting Entamoeba invadens and transfected Entamoeba histolytica trophozoites: localization of secretory vesicles, endoplasmic reticulum, and Golgi apparatus. Infect. Immun. 67:3073-3081.
11. Gray, M. W. G. Burger, and B. F. Land. 1999. Mitochondrial evolution. Science 283:1476-1481.
12. Hartl, F. U. 1996. Molecular chaperones in cellular protein folding. Nature 381:571-580.
13. Jang, Y.-J., D. Sanford, H. Y. Chung, S. Y. Back, and B. D. Stollar. 1998. The structural basis for DNA binding by an anti-DNA autoantibody. Mol. Immunol. 35:1207-1217.
14. Kamentsky, L. A., D. E. Burger, R. J. Gershman, L. D. Kamentsky, and E. Luther. 1997. Slide-based laser scanning cytometry. Acta Cytolog. 41:123-143.
15. +-dependent alcohol dehydrogenase gene of Entamoeba histolytica. Proc. Natl. Acad. Sci. USA 85:1782-1786.
16. Luna-Arias, J. P., R. Hernandez-Rivas, G. de Dios-Bravo, J. Garcia, L. Mendoza, and E. Orozco. 1999. The TATA-binding protein of Entamoeba histolytica: cloning of the gene location of the protein by immunofluores-cence and confocal microscopy. Microbiol. 145:33-40.
17. Mai, Z., S. Ghosh, M. Frisardi, B. Rosenthal, R. Rogers, and J. Samuelson. 1999. Hsp60 is targeted to a cryptic mitochondrion-derived organelle ("crypton") in the microaerophilic protozoan parasite Entamoeba histolytica. Mol. Cell. Biol. 19:2198-2205.
18. McNeil, J. A., C. V. Johnson, K. C. Carter, R. H. Singer, and J. B. Lawrence. 1991. Localizing DNA and RNA within nuclei and chromosomes by fluorescence in situ hybridization. Genet. Anal. Tech. Applic. 8:41-58.
19. Muller, M. 1993. The hydrogenosome. J. Gen. Microbiol. 139:2879-2889.
20. Orozco, E., R. Gharaibeh, A. M. Riveron, D. M. Delgadillo, M. Mercado, T. Sanchez, E. Gomez, Conde, M. A. Vargas, and R. Lopez-Revilla. 1997. A novel cytoplasmic structure containing DNA networks in Entamoeba histolytica trophozoites. Mol. Gen. Genet. 254:250-257.
21. Reeves, R. E. 1984. Metabolism of Entamoeba histolytica Schaudinn, 1903. Adv. Parasitol. 23:105-142.
22. +-dependent alcohol dehydrogenase gene. Biochim. Biophys. Acta 1306:23-26.
23. Rodriguez, M. A., R. M. Garcia-Perez, L. Mendoza, T. Sanchez, N. Guillen, and E. Orozco. 1998. The pyruvate:ferredoxin oxidoreductase enzyme is located in the plasma membrane and in a cytoplasmic structure in Entamoeba. Microb. Pathog. 25:1-10.
24. Roger, A. J., S. G. Svard, J. Tovar, C. G. Clark, M. W. Smith, F. D. Gillin, and M. L. Sogin. 1998. A mitochondrial-like chaperonin 60 gene in Giardia lamblia: evidence that diplomonads once harbored an endosymbiont related to the progenitor of mitochondria. Proc. Natl. Acad. Sci. USA 95:229-234.
25. Rosenthal, B., Z. Mai, D. Caplivski, S. Ghosh, H. de la Vega, T. Graf, and J. Samuelson. 1997. Evidence for the bacterial origin of genes encoding fermentation enzymes of the amitochondriate protozoan parasite Entamoeba histolytica. J. Bacteriol. 179:3736-3745.
26. Sehgal, D., V. Mittal, S. Ramachandran, S. K. Dhar, and A. Bhattacharya. 1994. Nucleotide sequence organization and analysts of the nuclear ribosomal DNA circle of the protozoan parasite Entamoeba histolytica. Mol. Biochem. Parasitol. 67:205-214.
27. Shapiro, H. Practical flow cytometry. Alton R. Liss, New York, N.Y.
28. Tovar, J., A. Fischer, and C. G. Clark. 1999. The mitosome, a novel organelle related to mitochondria in the amitochondrial parasite Entamoeba histolytica. Mol. Microbiol. 32:1013-1021.
29. Willhoeft, U., and E. Tannich. 1999. The electrophoretic karyotype of Entamoeba histolytica. Mol. Biochem. Parasitol. 99:41-53.
30. Willhoeft, U., and E. Tannich. 2000. Fluorescence microscopy and fluorescence in situ hybridization of Entamoeba histolytica nuclei to analyse mitosis and the localization of repetitive DNA. Mol. Biochem. Parasitol. 105:291-296, 2000
31. Yang, D., Y. Oyaizu, H. Oyaizu, G. J. Olsen, and C. R. Woese. 1985. Mitochondrial origins. Proc. Natl. Acad. Sci. USA 82:4443-4447.
32. Yang, W., E. Li, T. Kairong, and S. L. Stanley, Jr. 1994. Entamoeba histolytica has an alcohol dehydrogenase homologous to the multifunctional adhE gene product of Escherichia coli. Mol. Biochem. Parasitol. 64:253-260.