메뉴 건너뛰기




Volumn 68, Issue 7, 2000, Pages 3799-3807

Identification of three essential regulatory gene loci governing expression of Staphylococcus epidermidis polysaccharide intercellular adhesin and biofilm formation

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; POLYSACCHARIDE;

EID: 0033931998     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.7.3799-3807.2000     Document Type: Article
Times cited : (106)

References (45)
  • 2
    • 0028116666 scopus 로고
    • A method to isolate RNA from gram-positive bacteria and mycobacteria
    • Cheung, A. L., K. J. Eberhardt, and V. A. Fischetti. 1994. A method to isolate RNA from gram-positive bacteria and mycobacteria. Anal. Biochem. 222: 511-514.
    • (1994) Anal. Biochem. , vol.222 , pp. 511-514
    • Cheung, A.L.1    Eberhardt, K.J.2    Fischetti, V.A.3
  • 3
    • 0019989894 scopus 로고
    • Adherence of slime-producing strains of Staphylococcus epidermidis to smooth surfaces
    • Christensen, G. D., W. A. Simpson, A. L. Bisno, and E. H. Beachey. 1982. Adherence of slime-producing strains of Staphylococcus epidermidis to smooth surfaces. Infect. Immun. 37:318-326.
    • (1982) Infect. Immun. , vol.37 , pp. 318-326
    • Christensen, G.D.1    Simpson, W.A.2    Bisno, A.L.3    Beachey, E.H.4
  • 4
    • 0022377451 scopus 로고
    • Adherence of coagulase-negative staphylococci to plastic tissue culture plates: A quantitative model for the adherence of staphylococci to medical devices
    • Christensen, G. D., W. A. Simpson, J. J. Younger, L. M. Baddour, F. F. Barrett, D. M. Melton, and E. H. Beachey. 1985. Adherence of coagulase-negative staphylococci to plastic tissue culture plates: a quantitative model for the adherence of staphylococci to medical devices. J. Clin. Microbiol. 22: 996-1006.
    • (1985) J. Clin. Microbiol. , vol.22 , pp. 996-1006
    • Christensen, G.D.1    Simpson, W.A.2    Younger, J.J.3    Baddour, L.M.4    Barrett, F.F.5    Melton, D.M.6    Beachey, E.H.7
  • 5
    • 0033038971 scopus 로고    scopus 로고
    • Characterization of the relationship between polysaccharide intercellular adhesin and hemagglutination in Staphylococcus epidermidis
    • Fey, P. D., J. S. Ulphani, F. Götz, C. Heilmann, D. Mack, and M. E. Rupp. 1999. Characterization of the relationship between polysaccharide intercellular adhesin and hemagglutination in Staphylococcus epidermidis. J. Infect. Dis. 179:1561-1564.
    • (1999) J. Infect. Dis. , vol.179 , pp. 1561-1564
    • Fey, P.D.1    Ulphani, J.S.2    Götz, F.3    Heilmann, C.4    Mack, D.5    Rupp, M.E.6
  • 6
    • 0032540949 scopus 로고    scopus 로고
    • Characterization of the N-acetylglucosaminyltransferase activity involved in the biosynthesis of the Staphylococcus epidermidis polysaccharide intercellular adhesin
    • Gerke, C., A. Kraft, R. Süssmuth, O. Schweitzer, and F. Götz. 1998. Characterization of the N-acetylglucosaminyltransferase activity involved in the biosynthesis of the Staphylococcus epidermidis polysaccharide intercellular adhesin. J. Biol. Chem. 273:18586-18593.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18586-18593
    • Gerke, C.1    Kraft, A.2    Süssmuth, R.3    Schweitzer, O.4    Götz, F.5
  • 7
    • 0029955369 scopus 로고    scopus 로고
    • Insertional mutagenesis and recovery of interrupted genes of Streptococcus mutans by using transposon Tn917: Preliminary characterization of mutants displaying acid sensitivity and nutritional requirements
    • Gutierrez, J. A., P. J. Crowley, D. P. Brown, J. D. Hillman, P. Youngman, and A. S. Bleiweis. 1996. Insertional mutagenesis and recovery of interrupted genes of Streptococcus mutans by using transposon Tn917: preliminary characterization of mutants displaying acid sensitivity and nutritional requirements. J. Bacteriol. 178:4166-4175.
    • (1996) J. Bacteriol. , vol.178 , pp. 4166-4175
    • Gutierrez, J.A.1    Crowley, P.J.2    Brown, D.P.3    Hillman, J.D.4    Youngman, P.5    Bleiweis, A.S.6
  • 8
    • 0031936896 scopus 로고    scopus 로고
    • Further characterization of Staphylococcus epidermidis transposon mutants deficient in primary attachment or intercellular adhesion
    • Heilmann, C., and F. Götz. 1998. Further characterization of Staphylococcus epidermidis transposon mutants deficient in primary attachment or intercellular adhesion. Zentbl. Bakteriol. 287:69-83.
    • (1998) Zentbl. Bakteriol. , vol.287 , pp. 69-83
    • Heilmann, C.1    Götz, F.2
  • 9
    • 0030798156 scopus 로고    scopus 로고
    • Evidence for autolysin-mediated primary attachment of Staphylococcus epidermidis to a polystyrene surface
    • Heilmann, C., M. Hussain, G. Peters, and F. Götz. 1997. Evidence for autolysin-mediated primary attachment of Staphylococcus epidermidis to a polystyrene surface. Mol. Microbiol. 24:1013-1024.
    • (1997) Mol. Microbiol. , vol.24 , pp. 1013-1024
    • Heilmann, C.1    Hussain, M.2    Peters, G.3    Götz, F.4
  • 10
    • 0029888438 scopus 로고    scopus 로고
    • Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis
    • Heilmann, C., O. Schweitzer, C. Gerke, N. Vanittanakom, D. Mack, and F. Götz. 1996. Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis. Mol. Microbiol. 20:1083-1091.
    • (1996) Mol. Microbiol. , vol.20 , pp. 1083-1091
    • Heilmann, C.1    Schweitzer, O.2    Gerke, C.3    Vanittanakom, N.4    Mack, D.5    Götz, F.6
  • 12
    • 0031017470 scopus 로고    scopus 로고
    • A 140-kilodalton extracellular protein is essential for the accumulation of Staphylococcus epidermidis strains on surfaces
    • Hussain, M., M. Herrmann, C. von Eiff, F. Perdreau-Remington, and G. Peters. 1997. A 140-kilodalton extracellular protein is essential for the accumulation of Staphylococcus epidermidis strains on surfaces. Infect. Immun. 65:519-524.
    • (1997) Infect. Immun. , vol.65 , pp. 519-524
    • Hussain, M.1    Herrmann, M.2    Von Eiff, C.3    Perdreau-Remington, F.4    Peters, G.5
  • 13
    • 0027583376 scopus 로고
    • The slime of coagulase-negative staphylococci: Biochemistry and relation to adherence
    • Hussain, M., M. H. Wilcox, and P. J. White. 1993. The slime of coagulase-negative staphylococci: biochemistry and relation to adherence. FEMS Microbiol. Rev. 10:191-207.
    • (1993) FEMS Microbiol. Rev. , vol.10 , pp. 191-207
    • Hussain, M.1    Wilcox, M.H.2    White, P.J.3
  • 14
    • 0026513435 scopus 로고
    • Importance of medium and atmosphere type to both slime production and adherence by coagulase-negative staphylococci
    • Hussain, M., M. H. Wilcox, P. J. White, M. K. Faulkner, and R. C. Spencer. 1992. Importance of medium and atmosphere type to both slime production and adherence by coagulase-negative staphylococci. J. Hosp. Infect. 20:173-184.
    • (1992) J. Hosp. Infect. , vol.20 , pp. 173-184
    • Hussain, M.1    Wilcox, M.H.2    White, P.J.3    Faulkner, M.K.4    Spencer, R.C.5
  • 15
    • 0033392045 scopus 로고    scopus 로고
    • Molecular mechanisms of Staphylococcus epidermidis biofilm formation
    • Mack, D. 1999. Molecular mechanisms of Staphylococcus epidermidis biofilm formation. J. Hosp. Infect. 43(Suppl.):S113-S125.
    • (1999) J. Hosp. Infect. , vol.43 , Issue.SUPPL.
    • Mack, D.1
  • 17
    • 0030065904 scopus 로고    scopus 로고
    • The intercellular adhesin involved in biofilm accumulation of Staphylococcus epidermidis is a linear beta-1,6-linked glucosaminoglycan: Purification and structural analysis
    • Mack, D., W. Fischer, A. Krokotsch, K. Leopold, R. Hartmann, H. Egge, and R. Laufs. 1996. The intercellular adhesin involved in biofilm accumulation of Staphylococcus epidermidis is a linear beta-1,6-linked glucosaminoglycan: purification and structural analysis. J. Bacteriol. 178:175-183.
    • (1996) J. Bacteriol. , vol.178 , pp. 175-183
    • Mack, D.1    Fischer, W.2    Krokotsch, A.3    Leopold, K.4    Hartmann, R.5    Egge, H.6    Laufs, R.7
  • 18
    • 0029792827 scopus 로고    scopus 로고
    • Association of biofilm production of coagulase-negative staphylococci with expression of a specific polysaccharide intercellular adhesin
    • Mack, D., M. Haeder, N. Siemssen, and R. Laufs. 1996. Association of biofilm production of coagulase-negative staphylococci with expression of a specific polysaccharide intercellular adhesin. J. Infect. Dis. 174:881-884.
    • (1996) J. Infect. Dis. , vol.174 , pp. 881-884
    • Mack, D.1    Haeder, M.2    Siemssen, N.3    Laufs, R.4
  • 19
    • 0027978175 scopus 로고
    • Characterization of transposon mutants of biofilm-producing Staphylococcus epidermidis impaired in the accumulative phase of biofilm production: Genetic identification of a hexosamine-containing polysaccharide intercellular adhesin
    • Mack, D., M. Nedelmann, A. Krokotsch, A. Schwarzkopf, J. Heesemann, and R. Laufs. 1994. Characterization of transposon mutants of biofilm-producing Staphylococcus epidermidis impaired in the accumulative phase of biofilm production: genetic identification of a hexosamine-containing polysaccharide intercellular adhesin. Infect. Immun. 62:3244-3253.
    • (1994) Infect. Immun. , vol.62 , pp. 3244-3253
    • Mack, D.1    Nedelmann, M.2    Krokotsch, A.3    Schwarzkopf, A.4    Heesemann, J.5    Laufs, R.6
  • 20
    • 0032934733 scopus 로고    scopus 로고
    • Essential functional role of the polysaccharide intercellular adhesin of Staphylococcus epidermidis in hemagglutination
    • Mack, D., J. Riedewald, H. Rohde, T. Magnus, H. H. Feucht, H. A. Elsner, R. Laufs, and M. E. Rupp. 1999. Essential functional role of the polysaccharide intercellular adhesin of Staphylococcus epidermidis in hemagglutination. Infect. Immun. 67:1004-1008.
    • (1999) Infect. Immun. , vol.67 , pp. 1004-1008
    • Mack, D.1    Riedewald, J.2    Rohde, H.3    Magnus, T.4    Feucht, H.H.5    Elsner, H.A.6    Laufs, R.7    Rupp, M.E.8
  • 21
    • 0026751268 scopus 로고
    • Parallel induction by glucose of adherence and a polysaccharide antigen specific for plastic-adherent Staphylococcus epidermidis: Evidence for functional relation to intercellular adhesion
    • Mack, D., N. Siemssen, and R. Laufs. 1992. Parallel induction by glucose of adherence and a polysaccharide antigen specific for plastic-adherent Staphylococcus epidermidis: evidence for functional relation to intercellular adhesion. Infect. Immun. 60:2048-2057.
    • (1992) Infect. Immun. , vol.60 , pp. 2048-2057
    • Mack, D.1    Siemssen, N.2    Laufs, R.3
  • 22
    • 0000376664 scopus 로고
    • Identification of a cell cluster associated antigen specific for plastic-adherent Staphylococcus epidermidis which is functional related to intercellular adhesion
    • Mack, D., N. Siemssen, and R. Laufs. 1994. Identification of a cell cluster associated antigen specific for plastic-adherent Staphylococcus epidermidis which is functional related to intercellular adhesion. Zentbl. Bakteriol. Suppl. 26:411-413.
    • (1994) Zentbl. Bakteriol. Suppl. , vol.26 , pp. 411-413
    • Mack, D.1    Siemssen, N.2    Laufs, R.3
  • 23
    • 0031657783 scopus 로고    scopus 로고
    • The ica locus of Staphylococcus epidermidis encodes production of the capsular polysaccharide/adhesin
    • McKenney, D., J. Hübner, E. Muller, Y. Wang, D. A. Goldmann, and G. B. Pier. 1998. The ica locus of Staphylococcus epidermidis encodes production of the capsular polysaccharide/adhesin. Infect. Immun. 66:4711-4720.
    • (1998) Infect. Immun. , vol.66 , pp. 4711-4720
    • McKenney, D.1    Hübner, J.2    Muller, E.3    Wang, Y.4    Goldmann, D.A.5    Pier, G.B.6
  • 24
    • 0027475377 scopus 로고
    • Isolation and characterization of transposon mutants of Staphylococcus epidermidis deficient in capsular polysaccharide/adhesin and slime
    • Muller, E., J. Hübner, N. Gutierrez, S. Takeda, D. A. Goldmann, and G. B. Pier. 1993. Isolation and characterization of transposon mutants of Staphylococcus epidermidis deficient in capsular polysaccharide/adhesin and slime. Infect. Immun. 61:551-558.
    • (1993) Infect. Immun. , vol.61 , pp. 551-558
    • Muller, E.1    Hübner, J.2    Gutierrez, N.3    Takeda, S.4    Goldmann, D.A.5    Pier, G.B.6
  • 25
    • 0031895927 scopus 로고    scopus 로고
    • Generalized transduction for genetic linkage analysis and transfer of transposon insertions in different Staphylococcus epidermidis strains
    • Nedelmann, M., A. Sabottke, R. Laufs, and D. Mack. 1998. Generalized transduction for genetic linkage analysis and transfer of transposon insertions in different Staphylococcus epidermidis strains. Zentbl. Bakteriol. 287: 85-92.
    • (1998) Zentbl. Bakteriol. , vol.287 , pp. 85-92
    • Nedelmann, M.1    Sabottke, A.2    Laufs, R.3    Mack, D.4
  • 27
    • 0023034851 scopus 로고
    • Modulation of adherence of coagulase-negative staphylococci to Teflon catheters in vitro
    • Pascual, A., A. Fleer, N. A. Westerdaal, and J. Verhoef. 1986. Modulation of adherence of coagulase-negative staphylococci to Teflon catheters in vitro. Eur. J. Clin. Microbiol. 5:518-522.
    • (1986) Eur. J. Clin. Microbiol. , vol.5 , pp. 518-522
    • Pascual, A.1    Fleer, A.2    Westerdaal, N.A.3    Verhoef, J.4
  • 28
    • 0344562918 scopus 로고    scopus 로고
    • Functional studies of a fibrinogen binding protein from Staphylococcus epidermidis
    • Pei, L., M. Palma, M. Nilsson, B. Guss, and J. I. Flock. 1999. Functional studies of a fibrinogen binding protein from Staphylococcus epidermidis. Infect. Immun. 67:4525-4530.
    • (1999) Infect. Immun. , vol.67 , pp. 4525-4530
    • Pei, L.1    Palma, M.2    Nilsson, M.3    Guss, B.4    Flock, J.I.5
  • 29
    • 0026701976 scopus 로고
    • Hemagglutination and adherence to plastic by Staphylococcus epidermidis
    • Rupp, M. E., and G. L. Archer. 1992. Hemagglutination and adherence to plastic by Staphylococcus epidermidis. Infect. Immun. 60:4322-4327.
    • (1992) Infect. Immun. , vol.60 , pp. 4322-4327
    • Rupp, M.E.1    Archer, G.L.2
  • 30
    • 0027982653 scopus 로고
    • Coagulase-negative staphylococci: Pathogens associated with medical progress
    • Rupp, M. E., and G. L. Archer. 1994. Coagulase-negative staphylococci: pathogens associated with medical progress. Clin. Infect. Dis. 19:231-243.
    • (1994) Clin. Infect. Dis. , vol.19 , pp. 231-243
    • Rupp, M.E.1    Archer, G.L.2
  • 31
    • 0028791316 scopus 로고
    • Characterization of the hemagglutinin of Staphylococcus epidermidis
    • Rupp, M. E., N. Sloot, H. G. Meyer, J. Han, and S. Gatermann. 1995. Characterization of the hemagglutinin of Staphylococcus epidermidis. J. Infect. Dis. 172:1509-1518.
    • (1995) J. Infect. Dis. , vol.172 , pp. 1509-1518
    • Rupp, M.E.1    Sloot, N.2    Meyer, H.G.3    Han, J.4    Gatermann, S.5
  • 32
    • 0032899375 scopus 로고    scopus 로고
    • Characterization of the importance of polysaccharide intercellular adhesin/ hemagglutinin of Staphylococcus epidermidis in the pathogenesis of biomaterial-based infection in a mouse foreign body infection model
    • Rupp, M. E., J. S. Ulphani, P. D. Fey, K. Bartscht, and D. Mack. 1999. Characterization of the importance of polysaccharide intercellular adhesin/ hemagglutinin of Staphylococcus epidermidis in the pathogenesis of biomaterial-based infection in a mouse foreign body infection model. Infect. Immun. 67:2627-2632.
    • (1999) Infect. Immun. , vol.67 , pp. 2627-2632
    • Rupp, M.E.1    Ulphani, J.S.2    Fey, P.D.3    Bartscht, K.4    Mack, D.5
  • 33
    • 0032947603 scopus 로고    scopus 로고
    • Characterization of Staphylococcus epidermidis polysaccharide intercellular adhesin/hemagglutinin in the pathogenesis of intravascular catheter-associated infection in a rat model
    • Rupp, M. E., J. S. Ulphani, P. D. Fey, and D. Mack. 1999. Characterization of Staphylococcus epidermidis polysaccharide intercellular adhesin/hemagglutinin in the pathogenesis of intravascular catheter-associated infection in a rat model. Infect. Immun. 67:2656-2659.
    • (1999) Infect. Immun. , vol.67 , pp. 2656-2659
    • Rupp, M.E.1    Ulphani, J.S.2    Fey, P.D.3    Mack, D.4
  • 35
    • 0028269740 scopus 로고
    • Comparative analysis of a biofilm-forming Staphylococcus epidermidis strain and its adhesion-positive, accumulation-negative mutant M7
    • Schumacher-Perdreau, F., C. Heilmann, G. Peters, F. Götz, and G. Pulverer. 1994. Comparative analysis of a biofilm-forming Staphylococcus epidermidis strain and its adhesion-positive, accumulation-negative mutant M7. FEMS Microbiol. Lett. 117:71-78.
    • (1994) FEMS Microbiol. Lett. , vol.117 , pp. 71-78
    • Schumacher-Perdreau, F.1    Heilmann, C.2    Peters, G.3    Götz, F.4    Pulverer, G.5
  • 36
    • 0027259064 scopus 로고
    • Phenotypical and genotypical characterization of epidemic clumping factor-negative, oxacillin-resistant Staphylococcus aureus
    • Schwarzkopf, A., H. Karch, H. Schmidt, W. Lenz, and J. Heesemann. 1993. Phenotypical and genotypical characterization of epidemic clumping factor-negative, oxacillin-resistant Staphylococcus aureus. J. Clin. Microbiol. 31: 2281-2285.
    • (1993) J. Clin. Microbiol. , vol.31 , pp. 2281-2285
    • Schwarzkopf, A.1    Karch, H.2    Schmidt, H.3    Lenz, W.4    Heesemann, J.5
  • 37
    • 0022407696 scopus 로고
    • Complete nucleotide sequence of macrolide-lincosamide-streptogramin B- Resistance transposon Tn917 in Streptococcus faecalis
    • Shaw, J. H., and D. B. Clewell. 1985. Complete nucleotide sequence of macrolide-lincosamide-streptogramin B- resistance transposon Tn917 in Streptococcus faecalis. J. Bacteriol. 164:782-796.
    • (1985) J. Bacteriol. , vol.164 , pp. 782-796
    • Shaw, J.H.1    Clewell, D.B.2
  • 38
    • 0032130852 scopus 로고    scopus 로고
    • Increasing bacteremia due to coagulase-negative staphylococci: Fiction or reality?
    • Thylefors, J. D., S. Harbarth, and D. Pittet. 1998. Increasing bacteremia due to coagulase-negative staphylococci: fiction or reality? Infect. Control Hosp. Epidemiol. 19:581-589.
    • (1998) Infect. Control Hosp. Epidemiol. , vol.19 , pp. 581-589
    • Thylefors, J.D.1    Harbarth, S.2    Pittet, D.3
  • 39
    • 0023884459 scopus 로고
    • Isolation and characterization of a capsular polysaccharide adhesin from Staphylococcus epidermidis
    • Erratum, 158:268
    • Tojo, M., N. Yamashita, D. A. Goldmann, and G. B. Pier. 1988. Isolation and characterization of a capsular polysaccharide adhesin from Staphylococcus epidermidis. J. Infect. Dis. 157:713-722. (Erratum, 158:268.)
    • (1988) J. Infect. Dis. , vol.157 , pp. 713-722
    • Tojo, M.1    Yamashita, N.2    Goldmann, D.A.3    Pier, G.B.4
  • 40
    • 0345514343 scopus 로고    scopus 로고
    • Public Health Service: National nosocomial infectious surveillance (NNIS) report. Data summary from October 1986-April 1996, issued May 1996
    • U.S. Department of Health and Human Services. 1996. Public Health Service: National nosocomial infectious surveillance (NNIS) report. Data summary from October 1986-April 1996, issued May 1996. Am. J. Infect. Control 24:380-388.
    • (1996) Am. J. Infect. Control , vol.24 , pp. 380-388
  • 41
    • 0038852996 scopus 로고    scopus 로고
    • Public Health Service: National nosocomial infectious surveillance (NNIS) report. Data summary from October 1986-April 1997, issued May 1997
    • U.S. Department of Health and Human Services. 1997. Public Health Service: National nosocomial infectious surveillance (NNIS) report. Data summary from October 1986-April 1997, issued May 1997. Am. J. Infect. Control 24:477-487.
    • (1997) Am. J. Infect. Control , vol.24 , pp. 477-487
  • 42
    • 0025342589 scopus 로고
    • A new class of conjugative plasmid in Staphylococcus aureus
    • Udo, E. E., and W. B. Grubb. 1990. A new class of conjugative plasmid in Staphylococcus aureus. J. Med. Microbiol. 31:207-212.
    • (1990) J. Med. Microbiol. , vol.31 , pp. 207-212
    • Udo, E.E.1    Grubb, W.B.2
  • 43
    • 0025501771 scopus 로고
    • Conjugal transfer of plasmid pWBG637 from Staphylococcus aureus to Staphylococcus epidermidis and Streptococcus faecalis
    • Udo, E. E., and W. B. Grubb. 1990. Conjugal transfer of plasmid pWBG637 from Staphylococcus aureus to Staphylococcus epidermidis and Streptococcus faecalis. FEMS Microbiol. Lett. 60:183-187.
    • (1990) FEMS Microbiol. Lett. , vol.60 , pp. 183-187
    • Udo, E.E.1    Grubb, W.B.2
  • 44
    • 0030042535 scopus 로고    scopus 로고
    • Ultrastructural organization and regulation of a hiomaterial adhesin of Staphylococcus epidermidis
    • Veenstra, G. J., F. F. Cremers, H. van Dijk, and A. Fleer. 1996. Ultrastructural organization and regulation of a hiomaterial adhesin of Staphylococcus epidermidis. J. Bacteriol. 178:537-541.
    • (1996) J. Bacteriol. , vol.178 , pp. 537-541
    • Veenstra, G.J.1    Cremers, F.F.2    Van Dijk, H.3    Fleer, A.4
  • 45
    • 0032896896 scopus 로고    scopus 로고
    • A novel mechanism of phase variation of virulence in Staphylococcus epidermidis: Evidence for control of the polysaccharide intercellular adhesin synthesis by alternating insertion and excision of the insertion sequence element IS256
    • Ziebuhr, W., V. Krimmer, S. Rachid, I. Lössner, F. Götz, and J. Hacker. 1999. A novel mechanism of phase variation of virulence in Staphylococcus epidermidis: evidence for control of the polysaccharide intercellular adhesin synthesis by alternating insertion and excision of the insertion sequence element IS256. Mol. Microbiol. 32:345-356.
    • (1999) Mol. Microbiol. , vol.32 , pp. 345-356
    • Ziebuhr, W.1    Krimmer, V.2    Rachid, S.3    Lössner, I.4    Götz, F.5    Hacker, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.