Paclitaxel exposure time determines the nature of the interaction with radiation in HeLa cellsthe role of apoptosis

European Journal of Cancer

Volumn 36, Issue 11, 2000, Pages 1426-1432

  Yildiz, F ^a,b   Perez, R ^a   Redpath, J L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Apoptosis; HeLa cells; Paclitaxel; Radiation

Indexed keywords

PACLITAXEL;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL SURVIVAL; DOSE TIME EFFECT RELATION; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RADIATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HELA CELLS; HUMANS; PACLITAXEL; RADIATION-SENSITIZING AGENTS; TIME FACTORS; TUMOR STEM CELL ASSAY;

EID: 0033931439     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(00)00115-5     Document Type: Article

References (23)

1. Rowinsky E.K., Donehower R.C. Paclitaxel (Taxol). N. Engl. J. Med. 332:1995;1004-1014.
2. Chen D.M., Paley P.J., Potish R.A., Twiggs L.B. Phase I trial of Taxol as a radiation sensitizer with cisplatin in advanced cervical cancer. Gynecol. Oncol. 67:1997;131-136.
3. Choy H., Rodriguez F.F., Koester S., Hilsenbeck S., Von Hoff D.D. Investigation of Taxol as a potential radiation sensitizer. Cancer. 71:1993;3774-3778.
4. Formenti S.C., Danenberg P.F. Paclitaxel-induced radiosensitization. myth or reality? Adv. Oncol. 51:1999;25-29.
5. Geard C.R., Jones J.M. Radiation and Taxol effects in synchronized human cervical carcinoma cells. Int. J. Radiat. Oncol. Biol. Phys. 29:1994;565-569.
6. Gorodetzsky R., Levdansky L., Ringel I., Vexler A. Paclitaxel-induced modification of the effects of radiation and alterations in the cell cycle in normal and tumor mammalian cells. Radiat. Res. 150:1998;283-291.
7. Gupta N., Hu L.J., Deen D.F. Cytotoxicity and cell-cycle effects of paclitaxel when used as a single agent and in combination with ionizing radiation. Int. J. Radiat. Oncol. Biol. Phys. 37:1997;885-895.
8. Hennequin C., Giocanti N., Favaudon N. Interaction of ionizing radiation with paclitaxel (taxol) and docetaxel (taxotere) in HeLa and SQ20B cells. Cancer Res. 56:1996;1842-1850.
9. Ingram M.J., Redpath J.L. Subadditive interaction of radiation and taxol in vitro. Int. J. Radiat. Oncol. Biol. Phys. 37:1997;1139-1144.
10. Leonard C.E., Chan D.C., Chou T.-C., Kumar R., Bunn P.A. Paclitaxel enhances in vitro radiosensitivity of squamous carcinoma cell lines of the head and neck. Cancer Res. 56:1996;5198-5204.
11. Liebmann J., Cook J.A., Fisher J., Teague D., Mitchell J.B. Changes in radiation survival curve parameters in human and rodent cells exposed to paclitaxel (Taxol). Int. J. Radiat. Oncol. Biol. Phys. 29:1994;559-564.
12. Liebmann J., Herscher J., Fisher J., Teague D., Cook J.A. Antagonism of paclitaxel toxicity by X-rays. implications for combined modality therapy Int. J. Oncol. 8:1996;991-996.
13. Liebmann J., Cook J.A., Fisher J., Teague D., Mitchell J.B. In vitro studies of taxol as a radiation sensitizer in human tumor cells. J. Nat. Cancer Inst. 84:1994;441-446.
14. Minarik L., Hall E.J. Taxol in combination with acute and low dose-rate irradiation. Radiother. Oncol. 32:1994;124-128.
15. Rosenthal DI, Okani O, Truelson JM, et al. Intensive radiation therapy concurrent with up to 7-week continuous-infusion paclitaxel for locally advanced solid tumors: phase I studies. Semin Oncol 1997, 24(Suppl. 2), S2-81-S2-84.
16. Tischler R.B., Geard C.R., Hall E.J., Schiff P.B. Taxol sensitizes human astrocytoma cells to radiation. Cancer Res. 52:1992;3495-3497.
17. Zanelli G.D., Quaia M., Robieux I.et al. Paclitaxel as a radiosensitizer. a proposed schedule of administration based on in vitro data and pharmacokinetic calculations Eur. J. Cancer. 33:1997;486-492.
18. Jung M., Kern F.G., Jorgensen T.J., McCleskey S.W., Blair O.C., Dritschillo A. Fibroblast growth factor-4 enhanced G2 arrest and cell survival following ionizing radiation. Cancer Res. 54:1994;5194-5197.
19. Talwar N., Redpath J.L. Schedule dependence of the interaction of radiation and taxol in HeLa cells. Radiat. Res. 148:1997;48-53.
20. Taylor I.W. A rapid single step staining technique for DNA analysis by flow microfluorimetry. J. Histochem. Cytochem. 28:1980;1021-1024.
21. Chen C.H., Zhang J., Ling C.C. Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. Radiat. Res. 139:1994;307-315.
22. Thigpen T., Vance R., Khansur T., Malamud F. The role of paclitaxel in the management of patients with carcinoma of the cervix. Semin. Oncol. 24(Suppl. 2):1997;S2-41. S2-46.
23. Vogt H.-G., Martin T., Kolotas C., Schneider L., Strassman G., Zamboglou N. Simultaneous paclitaxel and radiotherapy. initial clinical experience in lung cancer and other malignancies Semin. Oncol. 24(Suppl. 12):1997;S12-101. S12-105.