The brain-heart axis in the perception of cardiac pain: The elusive link between ischaemia and pain

Annals of Medicine

Volumn 32, Issue 5, 2000, Pages 350-364

  Rosen, S D ^a   Camici, P G ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Angina; Myocardial ischaemia; Positron emission tomography; Syndrome X; Visceral pain

Indexed keywords

ADRENERGIC TRANSMISSION; ANGIOCARDIOGRAPHY; ARTICLE; AUTONOMIC NEUROPATHY; BRAIN BLOOD FLOW; BRAIN SCINTISCANNING; CINGULATE GYRUS; CLINICAL FEATURE; EXERCISE ELECTROCARDIOGRAPHY; FRONTAL LOBE; HEART MUSCLE ISCHEMIA; HUMAN; NOCICEPTIVE STIMULATION; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SYNDROME X; THALAMUS; THORAX PAIN;

EID: 0033931182     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853890008995938     Document Type: Article

References (61)

1. Transmural myocardial perfusion
2. The conceptualisation of cardiac pain as a non-specific and unreliable alarm system
3. Supraspinal mechanisms of visceral representation
4. The neuroanatomy of cardiac nociceptive pathways
5. Visceral pain: A review of experimental studies
6. Functional organization of central pathways regulating the cardiovascular system
7. Cardiac Pain. Anatomic pathways and physiologic mechanisms
8. Physiological significance of sympathetic resection in Basedow's disease, epilepsy, idiotism and glaucoma
9. Epidural spinal electrical stimulation in severe angina pectoris
10. Myocardial ischaemia and chest pain: A misunderstood and oversimplified relationship?
11. Remarks on angina pectoris
12. Painless acute infarction of the heart
13. Incidence and prognosis of unrecognised myocardial infarction: An update on the Framingham study
14. Transient asymptomatic ST segment depression during daily activity
15. Myocardial ischaemia during daily life in patients with stable angina: Its relation to symptoms and heart rate changes
16. Current concepts, myocardial ischemia: Silent or symptomatic
17. Silent ischemia as a marker for early unfavorable outcome in patients with unstable angina
18. Prognostic significance of ischemic episodes in patients with previous myocardial infarction
19. Silent ischemia on Holter monitoring predicts mortality in high risk post infarction patients
20. Life threatening ventricular tachycardia and fibrillation induced by painless myocardial ischemia during exercise testing
21. Is 'silent' myocardial ischemia really as severe as symptomatic ischemia? The analytical effect of patient selection biases
22. Detection of silent myocardial ischemia in diabetes mellitus
23. Differences in autonomic function in patients with silent and symptomatic myocardial ischaemia
24. Endogenous opioid peptides and pain mechanisms: A complex relationship
25. Mechanisms of pain perception in patients with silent myocardial ischemia
26. Pain perception and endogenous pain modulation in angina pectoris
27. Plasma beta-endorphin levels in silent myocardial ischemia induced by exercise
28. Correlation between beta-endorphin plasma levels and anginal symptoms in patients with coronary artery disease
29. Silent myocardial ischemia: Is the person or the event silent?
30. Imaging functional anatomy
31. Nonoxidative glucose consumption during focal physiologic neural activity
32. Circulatory and metabolic correlates of brain function in normal humans
33. Activity-dependent energy metabolism in rat posterior pituitary primarily reflects sodium pump activity
34. Central neural correlates of angina pectoris as a model of visceral pain
35. Beta adrenergic regulation of amine precursor amino-acid transport across the blood-brain barrier
36. Physical performance of a positron tomograph for brain imaging with retractable septa
37. The relationship between local and global changes in PET scans
38. Comparing functional (PET) images: Assessment of significant change
39. Localisation in PET images: Direct fitting of the intercommissural (AC- PC) line
40. 18F-fluorodeoxyglucose in postischemic myocardium of patients with exercise-induced angina
41. Silent ischaemia as a central problem: Regional brain activation compared in silent and painful myocardial ischaemia
42. The gate control theory of pain mechanisms. A re-examination and a re- statement
43. Anterior cingulate cortex in rodents: Connections, visceral control functions and implications for emotion
44. Rat medial frontal cortex: A visceral motor region with a direct projection to the solitary nucleus
45. Efferent projections of the inferolimbic cortex of the rat
46. Cingulate cortex of the rhesus monkey: II. cortical afferents
47. Connections of the monkey cingulate cortex
48. Cortical and subcortical localization of response to pain in man using positron emission tomography
49. Multiple representations of pain in human cerebral cortex
50. Angina pectoris: A syndrome caused by anoxemia of the myocardium
51. Insights into the pathophysiology of syndrome X obtained using positron emission tomography (PET)
52. Pathophysiological dilemma of syndrome X
53. Is altered cardiac sensation responsible for chest pain in patients with normal coronary arteries? Clinical observation during cardiac catheterisation
54. Abnormal cardiac sensitivity in patients with chest pain and normal coronary arteries
55. Intracoronary adenosine causes angina pectoris like pain - an inquiry into the nature of visceral pain
56. Lower threshold for adenosine-induced chest pain in patients with angina and normal coronary angiograms
57. Absence of myocardial dysfunction during pacing stress in patients with syndrome X
58. Investigation of the mechanism of chest pain in patients with angiographically normal coronary arteries using transesophageal dobutamine stress echo-cardiography