Mycophenolate mofetil in stem cell transplant patients in relation to plasma level of active metabolite

Clinical Biochemistry

Volumn 33, Issue 3, 2000, Pages 203-208

  Kiehl, Michael G ^a   Shipkova, Maria ^b   Basara, Nadezda ^a   Blau, Igor W ^a   Schütz, Ekkehard ^b   Armstrong, Victor W ^b   Oellerich, Michael ^b   Fauser, Axel A ^a  

^a Bone Marrow Transplant U Dr O ^*  (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

AGvHD treatment; Bone marrow transplantation; Graft versus host disease; Mycophenolate mofetil; Mycophenolic acid; Stem cell transplantation

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; ETOPOSIDE; METHOTREXATE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE;

ARTICLE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; GRAFT VERSUS HOST REACTION; HUMAN; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; WHOLE BODY RADIATION;

DRUG THERAPY, COMBINATION; GLUCURONATES; GLUCURONIDES; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MYCOPHENOLIC ACID; PROSPECTIVE STUDIES; TISSUE DONORS;

EID: 0033930360     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(00)00053-9     Document Type: Article

References (30)

1. Thomas E.D. Marrow transplantation for malignant diseases. J Clin Oncol. 1:1983;517.
2. Kernan N.A., Bartsch G., Ash R.C., et al. Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program. N Engl J Med. 328:1993;593.
3. Thomas E.D., Storb R., Clift R.A., et al. Bone-marrow transplantation. N Engl J Med. 292:1975;895.
4. Anasetti C., Hansen J.A. Bone marrow transplantation from HLA-partially matched related donors and unrelated volunteer donors. Forman S.J., Blume K.G., Thomas E.D. Bone marrow transplantation. 1994;665 Blackwell Scientific Publications, Oxford.
5. Beatty P.G., Hansen J.A., Longton G.M., et al. Marrow transplantation from HLA-matched unrelated donors for treatment of hematologic malignancies. Transplantation. 51:1991;443.
6. Hansen J.A., Clift R.A., Thomas E.D., Buckner C.D., Storb R., Giblett E.R. Transplantation of marrow from an unrelated donor to a patient with acute leukemia. N Engl J Med. 303:1980;565.
7. Ash R.C., Casper J.T., Chitambar C.R., et al. Successful allogeneic transplantation of T-cell-depleted bone marrow from closely HLA-matched unrelated donors. N Engl J Med. 322:1990;485.
8. McGlave P., Bartsch G., Anasetti C., et al. Unrelated donor marrow transplantation therapy for chronic myelogenous leukemia initial experience of the National Marrow Donor Program . Blood. 81:1993;543.
9. Nademanee A., Schmidt G.M., Parker P., et al. The outcome of matched unrelated donor bone marrow transplantation in patients with hematologic malignancies using molecular typing for donor selection and graft-versus-host disease prophylaxis regimen of cyclosporine, methotrexate, and prednisone. Blood. 86:1995;1228.
10. Storb R., Pepe M., Anasetti C., et al. What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants? Blood. 76:1990;1037.
11. Anasetti C., Etzioni R., Petersdorf E.W., Martin P.J., Hansen J.A. Marrow transplantation from unrelated volunteer donors. Ann Rev Med. 46:1995;169-179.
12. Sollinger H.W. Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group. Transplantation. 60:1995;225.
13. Basara N., Blau I.W., Kiehl M.G., et al. Efficacy and safety of mycophenolate mofetil for the treatment of acute and chronic GVHD in bone marrow transplant recipient. Transplant Proc. 30:1998;4087.
14. Basara N., Blau I.W., Römer E., et al. Mycophenolate mofetil for the treatment of acute and chronic GVHD in bone marrow transplant patients. Bone Marrow Transplant. 22:1998;61-68.
15. Weber L.T., Shipkova M., Lamersdorf T., et al. Pharmacokinetics of mycophenolic acid (MPA) and determinants of MPA free fraction in pediatric and adult renal transplant recipients. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients. J Am Soc Nephrol. 9:1998;1511.
16. Bullingham R.E.S., Nicholls A.J., Kamm B.R. Clinical pharmacokinetics of mycophenolate mofetil. Clin Pharmacokinet. 34:1998;429-455.
17. Przepiorka D., Weisdorf D., Martin P., et al. 1994 Consensus Conference on Acute GVHD Grading. Bone Marrow Transplant. 15:1995;825.
18. Shipkova M., Niedmann P.D., Armstrong V.W., et al. Simultaneous determination of mycophenolic acid and its glucuronide in human plasma using a simple high-performance liquid chromatography. Clin Chem. 44:1998;1481.
19. Martin P.J., Schoch G., Fisher L., et al. A retrospective analysis of therapy for acute graft-versus-host disease initial treatment . Blood. 76:1990;1464.
20. Castelo-Branco C. Management of osteoporosis. An overview. Drugs Aging. 12:(Suppl 1):1998;25-32.
21. Eastell R., Boyle I.T., Compston J., et al. Management of male osteoporosis report of the UK Consensus Group . QJM. 91:1998;71.
22. Moe S.M. The treatment of steroid-induced bone loss in transplantation. Curr Opin Nephrol Hypertens. 6:1997;544.
23. Picado C., Luengo M. Corticosteroid-induced bone loss. Prevention and management. Drug Safety. 15:1996;347.
24. Byers V.S., Henslee P.J., Kernan N.A., et al. Use of an anti-pan T-lymphocyte ricin a chain immunotoxin in steroid- resistant acute graft-versus-host disease. Blood. 75:1990;1426.
25. Herve P., Racadot E., Wijdenes J., et al. Monoclonal anti TNF alpha antibody in the treatment of acute GvHD refractory both to corticosteroids and anti IL-2 R antibody. Bone Marrow Transplant. 7:(Suppl 2):1991;149.
26. Herve P., Wijdenes J., Bergerat J.P., et al. Treatment of corticosteroid resistant acute graft-versus-host disease by in vivo administration of anti-interleukin-2 receptor monoclonal antibody (B-B10). Blood. 75:1990;1017.
27. Neylan J.F. Immunosuppressive therapy in high-risk transplant patients dose-dependent efficacy of mycophenolate mofetil in African-American renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group. Transplantation. 64:1997;1277.
28. Shaw L.M., Nicholls A., Hale M., et al. Therapeutic monitoring of mycophenolic acid. A consensus panel report. Clin Biochem. 31:1998;317-322.
29. Strassburg C.P., Nguyen N., Manns M.P., Turkey R.H. UDP-glucuronosyltransferase activity in human liver and colon. Gastroenterology. 116:1999;149-160.
30. Radominska-Pandya A., Little J.M., Pandya J.T., et al. UDP-glucuronosyltransferases in human intestinal mucosa. Biochim Biophys Acta. 1394:1998;199-208.