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Volumn 6, Issue SUPPL. 3, 2000, Pages

Bispecific antibodies in cancer therapy

Author keywords

[No Author keywords available]

Indexed keywords

BISPECIFIC ANTIBODY; HYBRID PROTEIN; MONOCLONAL ANTIBODY; TUMOR ANTIGEN;

EID: 0033928749     PISSN: 15289117     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (14)

References (14)
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    • Press, O.W.1    Eary, J.F.2    Applebaum, F.R.3
  • 2
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    • 131i] anti-B1 (anti-CD20) antibody
    • 131I] anti-B1 (anti-CD20) antibody. N Engl J Med 1993;329:459-465.
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  • 3
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    • Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER 2 overexpressing metastatic breast cancer (HER2+/MBC) markedly increased anticancer activity: A randomized, multinational controlled phase III trial
    • abstr
    • Slamon DJ et al. Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER 2 overexpressing metastatic breast cancer (HER2+/MBC) markedly increased anticancer activity: a randomized, multinational controlled phase III trial. Proc Am Soc Clin Oncol 1998;17:98a (abstr).
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Slamon, D.J.1
  • 4
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    • Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: A phase I study of an anti-CD33 calicheamicin immunoconjugate
    • Sievers EL, Appelbaum FR, Spielberger RT et al. Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate. Blood 1999;93:3678-3684.
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    • Sievers, E.L.1    Appelbaum, F.R.2    Spielberger, R.T.3
  • 5
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    • Randomised trial of monoclonal antibody for adjuvant therapy of resected Duke's c colorectal carcinoma: German Cancer Aid 17-1A Study Group
    • Riethmuller G et al. Randomised trial of monoclonal antibody for adjuvant therapy of resected Duke's C colorectal carcinoma: German Cancer Aid 17-1A Study Group. Lancet 1994;343:1177-1183.
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    • Riethmuller, G.1
  • 6
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    • Immune response to the carcinoembryonic antigen in patients treated with an anti-idiotype antibody vaccine
    • Foon KA et al. Immune response to the carcinoembryonic antigen in patients treated with an anti-idiotype antibody vaccine. J Clin Invest 1995;96:334-332.
    • (1995) J Clin Invest , vol.96 , pp. 334-1332
    • Foon, K.A.1
  • 8
    • 0030796916 scopus 로고    scopus 로고
    • Induction of multiple anti-c-erbB2 specificities accompanies a classical idiotypic cascade following 2B1 bispecific monoclonal antibody treatment
    • Clark JI et al. Induction of multiple anti-c-erbB2 specificities accompanies a classical idiotypic cascade following 2B1 bispecific monoclonal antibody treatment. Cancer Immunol Immunother 1997;44:265-272.
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    • Clark, J.I.1
  • 9
    • 0031942906 scopus 로고    scopus 로고
    • Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu
    • Adams GP, Schier R, McCall AM et al. Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu. Br J Cancer 1998;77:1405-1412.
    • (1998) Br J Cancer , vol.77 , pp. 1405-1412
    • Adams, G.P.1    Schier, R.2    McCall, A.M.3
  • 10
    • 0030575802 scopus 로고    scopus 로고
    • Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site
    • Schier R et al. Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site. J Mol Biol 1996;263:551-567.
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    • Schier, R.1
  • 11
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    • Modeling analysis of the global and microscopic distribution of immunoglobulin G, F(ab')2 and Fab in tumors
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  • 12
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    • Micropharmacology of monoclonal antibodies in solid tumors: Direct experimental evidence for binding site barrier
    • Juweid MN, Paik R, Perez-Barele C et al. Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for binding site barrier. Cancer Res 1992;52:5144-5153.
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    • Juweid, M.N.1    Paik, R.2    Perez-Barele, C.3
  • 13
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    • Isolation and characterization of an anti-CD16 single-chain Fv fragment and construction of an anti-HER2/neu/anti-CD16 bispecific scFv that triggers CD16-dependent tumor cytolysis
    • McCall AM, Adams GP, Amoroso AR et al. Isolation and characterization of an anti-CD16 single-chain Fv fragment and construction of an anti-HER2/neu/anti-CD16 bispecific scFv that triggers CD16-dependent tumor cytolysis. Molecular Immunology 1999;36:433-445.
    • (1999) Molecular Immunology , vol.36 , pp. 433-445
    • McCall, A.M.1    Adams, G.P.2    Amoroso, A.R.3
  • 14
    • 0031942906 scopus 로고    scopus 로고
    • Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu
    • Adams GP et al. Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu. Br J Cancer 1998;
    • (1998) Br J Cancer
    • Adams, G.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.