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Volumn 9, Issue 4, 2000, Pages 327-341

Presymptomatic genetic testing with an APP mutation in Early-onset Alzheimer disease: A descriptive study of sibship dynamics

Author keywords

Alzheimer disease; Genetic counseling; Predictive testing

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

EID: 0033927573     PISSN: 10597700     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009406229745     Document Type: Review
Times cited : (8)

References (22)
  • 1
    • 0031918785 scopus 로고    scopus 로고
    • The genetics of Alzheimer disease: Current status and future prospects
    • Blacker D, Tanzi RE (1998) The genetics of Alzheimer disease: Current status and future prospects. Arch Neurol 55:294-296.
    • (1998) Arch Neurol , vol.55 , pp. 294-296
    • Blacker, D.1    Tanzi, R.E.2
  • 2
    • 0026310588 scopus 로고
    • The ethical justification for minimal paternalism in the use of the predictive test for Huntington's disease
    • DeGrazia D (1991) The ethical justification for minimal paternalism in the use of the predictive test for Huntington's disease. J Clin Ethics 2:219-228.
    • (1991) J Clin Ethics , vol.2 , pp. 219-228
    • DeGrazia, D.1
  • 4
    • 0343581405 scopus 로고    scopus 로고
    • APP Mutations Directory, January 26, 2000
    • Hardy J (2000) APP Mutations Directory, Alzheimer Research Forum On-line Resources at www. alzforum.org, January 26, 2000.
    • (2000)
    • Hardy, J.1
  • 5
    • 0026879650 scopus 로고
    • Presenile dementia and cerebral hemorrhage linked to a mutation at codon 692 of the B-amyloid precursor protein gene
    • Hendricks M, van Duijn CM, Cras P (1992) Presenile dementia and cerebral hemorrhage linked to a mutation at codon 692 of the B-amyloid precursor protein gene. Na Genet 1:218-221.
    • (1992) Na Genet , vol.1 , pp. 218-221
    • Hendricks, M.1    Van Duijn, C.M.2    Cras, P.3
  • 8
    • 0002797321 scopus 로고    scopus 로고
    • Genetic testing and counseling for early-onset autosomal dominant Alzheimer disease
    • Post SG, Whitehouse PJ (eds) Baltimore: Johns Hopkins University Press
    • Karlinsky H (1998) Genetic testing and counseling for early-onset autosomal dominant Alzheimer disease. In: Post SG, Whitehouse PJ (eds) Genetic Testing for Alzheimer Disease: Ethical and Clinical Issues. Baltimore: Johns Hopkins University Press, pp. 103-117.
    • (1998) Genetic Testing for Alzheimer Disease: Ethical and Clinical Issues , pp. 103-117
    • Karlinsky, H.1
  • 10
    • 0028794826 scopus 로고
    • Genetic counseling of a Swedish Alzheimer family with amyloid precursor protein mutation
    • Lannfelt L, Axelman K, Lilius L, Basun H (1995) Genetic counseling of a Swedish Alzheimer family with amyloid precursor protein mutation. Am J Hum Genet 56:332-335.
    • (1995) Am J Hum Genet , vol.56 , pp. 332-335
    • Lannfelt, L.1    Axelman, K.2    Lilius, L.3    Basun, H.4
  • 13
    • 0026907151 scopus 로고
    • A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of B-amyloid
    • Mullan MJ, Crawford F, Axelman K (1992) A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of B-amyloid. Nat Genet 1:345-347.
    • (1992) Nat Genet , vol.1 , pp. 345-347
    • Mullan, M.J.1    Crawford, F.2    Axelman, K.3
  • 14
    • 0025950987 scopus 로고
    • A mutation in the amyloid precurson protein associated with hereditary Alzheimer's disease
    • Murrell J, Farlow M, Ghetti B, Benson MD (1991) A mutation in the amyloid precurson protein associated with hereditary Alzheimer's disease. Science 254:97-99.
    • (1991) Science , vol.254 , pp. 97-99
    • Murrell, J.1    Farlow, M.2    Ghetti, B.3    Benson, M.D.4
  • 15
    • 0343581404 scopus 로고    scopus 로고
    • Early-onset Alzheimer disease caused by a new mutation (V717L) in the APP gene
    • Murrell JR, Hake A, Quaid KA, Farlow MR (2000) Early-onset Alzheimer disease caused by a new mutation (V717L) in the APP gene. Arch Neurol.
    • (2000) Arch Neurol.
    • Murrell, J.R.1    Hake, A.2    Quaid, K.A.3    Farlow, M.R.4
  • 20
    • 0031037982 scopus 로고    scopus 로고
    • Preparing for presymptomatic DNA testing for early onset Alzheimer's disease/cerebral haemorrhage and hereditary Pick disease
    • Tibben A, Stevens M, Wert GMWR, Niermeijer MF, van Duijn CM, van Swieten JC (1997) Preparing for presymptomatic DNA testing for early onset Alzheimer's disease/cerebral haemorrhage and hereditary Pick disease. J Med Genet 34:63-72.
    • (1997) J Med Genet , vol.34 , pp. 63-72
    • Tibben, A.1    Stevens, M.2    Wert, G.M.W.R.3    Niermeijer, M.F.4    Van Duijn, C.M.5    Van Swieten, J.C.6
  • 21
    • 0025059035 scopus 로고
    • Ethical issues policy statement on Huntington's disease molecular genetics predictive test
    • World Federation of Neurology, Predictive Testing Committee, Research Group on Huntington's Chorea (1990) Ethical issues policy statement on Huntington's disease molecular genetics predictive test. J Med Genet 27:34-38.
    • (1990) J Med Genet , vol.27 , pp. 34-38
  • 22
    • 0028031125 scopus 로고
    • Guidelines for molecular genetics predictive test in Huntington Disease
    • World Federation of Neurology, Predictive Testing Committee, Research Group on Huntington's Chorea (1994) Guidelines for molecular genetics predictive test in Huntington Disease. Neurology 44:1533-1536.
    • (1994) Neurology , vol.44 , pp. 1533-1536


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.