Review: Lamina-associated polypeptide 2 isoforms and related proteins in cell cycle-dependent nuclear structure dynamics

Journal of Structural Biology

Volumn 129, Issue 2-3, 2000, Pages 335-345

  Dechat, Thomas ^a   Vlcek, Sylvia ^a   Foisner, Roland ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Chromosomes; Lamina associated polypeptide; Lamins; Mitosis; Nuclear envelope

Indexed keywords

CHROMOSOME PROTEIN; DOCKING PROTEIN; LAMIN B; LAMINA ASSOCIATED POLYPEPTIDE 2; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; CELL NUCLEUS MEMBRANE; CHROMATIN STRUCTURE; EMERY DREIFUSS MUSCULAR DYSTROPHY; GENETIC STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; REVIEW; XENOPUS;

EID: 0033926099     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsbi.2000.4212     Document Type: Article

References (70)

1. Alsheimer M., Fecher E., Benavente R. Nuclear envelope remodelling during rat spermiogenesis: Distribution and expression pattern of LAP2/thymopoietins. J. Cell. Sci. 111:1998;2227-2234.
2. Ashery-Padan R., Ulitzur N., Arbel A., Goldberg M., Weiss A. M., Maus N., Fisher P. A., Gruenbaum Y. Localization and posttranslational modifications of otefin, a protein required for vesicle attachment to chromatin, during Drosophila melanogaster development. Mol. Cell Biol. 17:1997a;4114-4123.
3. Ashery-Padan R., Weiss A. M., Feinstein N., Gruenbaum Y. Distinct regions specify the targeting of otefin to the nucleoplasmic side of the nuclear envelope. J. Biol. Chem. 272:1997b;2493-2499.
4. Berger R., Theodor L., Brok-Simoni F., Ben-Bassat H., Trakhtenbrot L., Shoham J., Rechavi G. Demonstration of thymopoietin transcripts in different hematopoietic cell lines. Acta Haematol. 93:1995;62-66.
5. Berger R., Theodor L., Shoham J., Gokkel E., Brok-Simoni F., Avraham K. B., Copeland N. G., Jenkins N. A., Rechavi G., Simon A. J. The characterization and localization of the mouse thymopoietin/lamina-associated polypeptide 2 gene and its alternatively spliced products. Genome Res. 6:1996;361-370.
6. Bione S., Maestrini E., Rivella S., Mancini M., Regis S., Romeo G., Toniolo D. Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy. Nature Genet. 8:1994;323-327.
7. Bonne G., Di Barletta M. R., Varnous S., Becane H. M., Hammouda E. H., Merlini L., Muntoni F., Greenberg C. R., Gary F., Urtizberea J. A., Duboc D., Fardeau M., Toniolo D., Schwartz K. Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy. Nature Genet. 21:1999;285-288.
8. Bridger J. M., Kill I. R., O'Farrell M., Hutchison C. J. Internal lamin structures within G1 nuclei of human dermal fibroblasts. J. Cell Sci. 104:1993;297-306.
9. Broers J. L., Machiels B. M., van Eys G. J., Kuijpers H. J., Manders E. M., van Driel R., Ramaekers F. C. Dynamics of the nuclear lamina as monitored by GFP-tagged A-type lamins. J. Cell Sci. 112:1999;3463-3475.
10. Buendia B., Courvalin J. C. Domain-specific disassembly and reassembly of nuclear membranes during mitosis. Exp. Cell. Res. 230:1997;133-144.
11. Cartegni L., di Barletta M. R., Barresi R., Squarzoni S., Sabatelli P., Maraldi N., Mora M., Di Blasi C., Cornelio F., Merlini L., Villa A., Cobianchi F., Toniolo D. Heart-specific localization of emerin: new insights into Emery-Dreifuss muscular dystrophy. Hum. Mol. Genet. 6:1997;2257-2264.
12. Chaudhary N., Courvalin J. C. Stepwise reassembly of the nuclear envelope at the end of mitosis. J. Cell Biol. 122:1993;295-306.
13. Dechat T., Gotzmann J., Stockinger A., Harris C. A., Talle M. A., Siekierka J. J., Foisner R. Detergent-salt resistance of LAP2alpha in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics. EMBO J. 17:1998;4887-4902.
14. Drummond S., Ferrigno P., Lyon C., Murphy J., Goldberg M., Allen T., Smythe C., Hutchison C. J. Temporal differences in the appearance of NEP-B78 and an LBR-like protein during Xenopus nuclear envelope reassembly reflect the ordered recruitment of functionally discrete vesicle types. J. Cell Biol. 144:1999;225-240.
15. Ellenberg J., Siggia E. D., Moreira J. E., Smith C. L., Presley J. F., Worman H. J., Lippincott-Schwartz J. Nuclear membrane dynamics and reassembly in living cells: Targeting of an inner nuclear membrane protein in interphase and mitosis. J. Cell Biol. 138:1997;1193-1206.
16. Ellis J. A., Craxton M., Yates J. R., Kendrick-Jones J. Aberrant intracellular targeting and cell cycle-dependent phosphorylation of emerin contribute to the Emery-Dreifuss muscular dystrophy phenotype. J. Cell Sci. 111:1998;781-792.
17. Ellis J. A., Yates J. R., Kendrick-Jones J., Brown C. A. Changes at P183 of emerin weaken its protein-protein interactions resulting in X-linked Emery-Dreifuss muscular dystrophy. Hum. Genet. 104:1999;262-268.
18. Fairley E. A., Kendrick-Jones J., Ellis J. A. The Emery-Dreifuss muscular dystrophy phenotype arises from aberrant targeting and binding of emerin at the inner nuclear membrane. J. Cell Sci. 112:1999;2571-2582.
19. Foisner R. Dynamic organisation of intermediate filaments and associated proteins during the cell cycle. Bioessays. 19:1997;297-305.
20. Foisner R., Gerace L. Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation. Cell. 73:1993;1267-1279.
21. Furukawa K. LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction. J. Cell Sci. 112:1999;2485-2492.
22. Furukawa K., Fritze C. E., Gerace L. The major nuclear envelope targeting domain of LAP2 coincides with its lamin binding region but is distinct from its chromatin interaction domain. J. Biol. Chem. 273:1998;4213-4219.
23. Furukawa K., Glass C., Kondo T. Characterization of the chromatin binding activity of lamina-associated polypeptide (LAP) 2. Biochem. Biophys. Res. Commun. 238:1997;240-246.
24. Furukawa K., Kondo T. Identification of the lamina-associated-polypeptide-2-binding domain of B-type lamin. Eur. J. Biochem. 251:1998;729-733.
25. Furukawa K., Pante N., Aebi U., Gerace L. Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope. EMBO J. 14:1995;1626-1636.
26. Gant T. M., Harris C. A., Wilson K. L. Roles of LAP2 proteins in nuclear assembly and DNA replication: Truncated LAP2beta proteins alter lamina assembly, envelope formation, nuclear size, and DNA replication efficiency in Xenopus laevis extracts. J. Cell Biol. 144:1999;1083-1096.
27. Gant T. M., Wilson K. L. Nuclear assembly. Annu. Rev. Cell Dev. Biol. 13:1997;669-695.
28. Gerace L., Foisner R. Integral membrane proteins and dynamic organization of the nuclear envelope. Trends Cell Biol. 4:1994;127-131.
29. Goldberg M., Harel A., Gruenbaum Y. The nuclear lamina: Molecular organization and interaction with chromatin. Crit. Rev. Eukaryote Gene Expression. 9:1999;285-293.
30. Goldberg M., Lu H., Stuurman N., Ashery-Padan R., Weiss A. M., Yu J., Bhattacharyya D., Fisher P. A., Gruenbaum Y., Wolfner M. F. Interactions among Drosophila nuclear envelope proteins lamin, otefin, and YA. Mol. Cell Biol. 18:1998;4315-4323.
31. Goldman A. E., Moir R. D., Montag-Lowy M., Stewart M., Goldman R. D. Pathway of incorporation of microinjected lamin A into the nuclear envelope. J. Cell Biol. 119:1992;725-735.
32. Gotzmann J., Foisner R. Lamins and lamin-binding proteins in functional chromatin organization. Crit. Rev. Eukaryote Gene Expression. 9:1999;257-265.
33. Harris C. A., Andryuk P. J., Cline S., Chan H. K., Natarajan A., Siekierka J. J., Goldstein G. Three distinct human thymopoietins are derived from alternatively spliced mRNAs. Proc. Natl. Acad. Sci. USA. 91:1994;6283-6287.
34. Harris C. A., Andryuk P. J., Cline S. W., Mathew S., Siekierka J. J., Goldstein G. Structure and mapping of the human thymopoietin (TMPO) gene and relationship of human TMPO beta to rat lamin-associated polypeptide 2. Genomics. 28:1995;198-205.
35. Hozak P., Sasseville A. M., Raymond Y., Cook P. R. Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells. J. Cell Sci. 108:1995;635-644.
36. Ishijima Y., Toda T., Matsushita H., Yoshida M., Kimura N. Expression of thymopoietin beta/lamina-associated polypeptide 2 (TP beta/LAP2) and its family proteins as revealed by specific antibody induced against recombinant human thymopoietin. Biochem. Biophys. Res. Commun. 226:1996;431-438.
37. Lang C., Paulin-Levasseur M., Gajewski A., Alsheimer M., Benavente R., Krohne G. Molecular characterization and developmentally regulated expression of Xenopus lamina-associated polypeptide 2 (XLAP2). J. Cell Sci. 112:1999;749-759.
38. Lopez J. M., Song K., Hirshfeld A. B., Lin H., Wolfner M. F. The Drosophila fs(1)Ya protein, which is needed for the first mitotic division, is in the nuclear lamina and in the envelopes of cleavage nuclei, pronuclei, and nonmitotic nuclei. Dev. Biol. 163:1994;202-211.
39. Lopez J. M., Wolfner M. F. The developmentally regulated Drosophila embryonic nuclear lamina protein 'Young Arrest' (fs(1)Ya) is capable of associating with chromatin. J. Cell Sci. 110:1997;643-651.
40. Lourim D., Krohne G. Lamin-dependent nuclear envelope reassembly following mitosis. Trends Cell Biol. 4:1994;324-318.
41. Maison C., Pyrpasopoulou A., Theodoropoulos P. A., Georgatos S. D. The inner nuclear membrane protein LAP1 forms a native complex with B-type lamins and partitions with spindle-associated mitotic vesicles. EMBO J. 16:1997;4839-4850.
42. Manilal S., Nguyen T. M., Morris G. E. Colocalization of emerin and lamins in interphase nuclei and changes during mitosis. Biochem. Biophys. Res. Commun. 249:1998a;643-647.
43. Manilal S., Recan D., Sewry C. A., Hoeltzenbein M., Llense S., Leturcq F., Deburgrave N., Barbot J., Man N., Muntoni F., Wehnert M., Kaplan J., Morris G. E. Mutations in Emery-Dreifuss muscular dystrophy and their effects on emerin protein expression. Hum. Mol. Genet. 7:1998b;855-864.
44. Manilal S., Sewry C. A., Pereboev A., Man N., Gobbi P., Hawkes S., Love D. R., Morris G. E. Distribution of emerin and lamins in the heart and implications for Emery-Dreifuss muscular dystrophy. Hum. Mol. Genet. 8:1999;353-359.
45. Manilal S., thi Man N., Sewry C. A., Morris G. E. The Emery-Dreifuss muscular dystrophy protein, emerin, is a nuclear membrane protein. Hum. Mol. Genet. 5:1996;801-808.
46. Marshall I. C. B., Wilson K. L. Nuclear envelope assembly after mitosis. Trends Cell Biol. 7:1997;69-74.
47. Martin L., Crimaudo C., Gerace L. cDNA cloning and characterization of lamina-associated polypeptide 1C (LAP1C), an integral protein of the inner nuclear membrane. J. Biol. Chem. 270:1995;8822-8828.
48. Mical T. I., Monteiro M. J. The role of sequences unique to nuclear intermediate filaments in the targeting and assembly of human lamin B: Evidence for lack of interaction of lamin B with its putative receptor. J. Cell Sci. 111:1998;3471-3485.
49. Moir R. D., Spann T. P., Goldman R. D. The dynamic properties and possible functions of nuclear lamins. Int. Rev. Cytol. 162B:1995;141-182.
50. Morris G. E., Manilal S. Heart to heart: From nuclear proteins to Emery-Dreifuss muscular dystrophy. Hum. Mol. Genet. 8:1999;1847-1851.
51. Nagano A., Koga R., Ogawa M., Kurano Y., Kawada J., Okada R., Hayashi Y. K., Tsukuhara T., Arahata K. Emerin deficiency at the nuclear membrane in patients with Emery-Dreyfuss muscular dystrophy. Nature Genet. 12:1996;254-259.
52. Neri L. M., Raymond Y., Giordano A., Capitani S., Martelli A. M. Lamin A is part of the internal nucleoskeleton of human erythroleukemia cells. J. Cell Physiol. 178:1999;284-295.
53. Ognibene A., Sabatelli P., Petrini S., Squarzoni S., Riccio M., Santi S., Villanova M., Palmeri S., Merlini L., Maraldi N. M. Nuclear changes in a case of X-linked Emery-Dreifuss muscular dystrophy. Muscle Nerve. 22:1999;864-869.
54. Ostlund C., Ellenberg J., Hallberg E., Lippincott-Schwartz J., Worman H. J. Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein. J. Cell Sci. 112:1999;1709-1719.
55. Paulin-Levasseur M., Blake D. L., Julien M., Rouleau L. The MAN antigens are non-lamin constituents of the nuclear lamina in vertebrate cells. Chromosoma. 104:1996;367-379.
56. Pugh G. E., Coates P. J., Lane E. B., Raymond Y., Quinlan R. A. Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells. J. Cell Sci. 110:1997;2483-2493.
57. Pyrpasopoulou A., Meier J., Maison C., Simos G., Georgatos S. D. The lamin B receptor (LBR) provides essential chromatin docking sites at the nuclear envelope. EMBO J. 15:1996;7108-7119.
58. Simos G., Georgatos S. D. The inner nuclear membrane protein p58 associates in vivo with a p58 kinase and the nuclear lamins. EMBO J. 11:1992;4027-4036.
59. Theodor L., Shoham J., Berger R., Gokkel E., Trachtenbrot L., Simon A. J., Brok-Simon F., Nir U., Ilan E., Zevin-Sonkin D., Friedman E., Rechavi G. Ubiquitous expression of a cloned murine thymopoietin cDNA. Acta Haematol. 97:1997;153-163.
60. Vigers G. P., Lohka M. J. A distinct vesicle population targets membranes and pore complexes to the nuclear envelope in Xenopus eggs. J. Cell Biol. 112:1991;545-556.
61. Vlcek S., Just H., Dechat T., Foisner R. Functional diversity of LAP2 and LAP2β in postmitotic chromosome association is caused by an a-specific nuclear targeting region. EMBO J. 18. 1999.
62. Wilson K. L. The nuclear envelope and disease. Trends Cell Biol. 3:2000.
63. Worman H. J., Evans C. D., Blobel G. The lamin B receptor of the nuclear envelope inner membrane: A polytopic protein with eight potential transmembrane domains. J. Cell Biol. 111:1990;1535-1542.
64. Worman H. J., Yuan J., Blobel G., Georgatos S. D. A lamin B receptor in the nuclear envelope. Proc. Natl. Acad. Sci. USA. 85:1988;8531-8534.
65. Yang L., Guan T., Gerace L. Integral membrane proteins of the nuclear envelope are dispersed throughout the endoplasmic reticulum during mitosis. J. Cell Biol. 137:1997a;1199-1210.
66. Yang L., Guan T., Gerace L. Lamin-binding fragment of LAP2 inhibits increase in nuclear volume during the cell cycle and progression into S phase. J. Cell Biol. 139:1997b;1077-1087.
67. Ye Q., Barton R. M., Worman H. J. Nuclear lamin-binding proteins. Herrmann H., Harris J. R. Subcellular Biochemistry: Intermediate Filaments. 1998;587-610 Plenum P, London.
68. Ye Q., Callebaut I., Pezhman A., Courvalin J. C., Worman H. J. Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR. J. Biol. Chem. 272:1997;14983-14989.
69. Ye Q., Worman H. J. Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane. J. Biol. Chem. 269:1994;11306-11311.
70. Ye Q., Worman H. J. Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1. J. Biol. Chem. 271:1996;14653-14656.