The inner nuclear membrane protein LAP1 forms a native complex with B-type lamins and partitions with spindle-associated mitotic vesicles

EMBO Journal

Volumn 16, Issue 16, 1997, Pages 4839-4850

  Maison, Christele ^a,b,d   Pyrpasopoulou, Athina ^a,c,d   Theodoropoulos, Panayiotis A ^d   Georgatos, Spyros D ^d  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b INSTITUT CURIE   (France)

^c ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^d UNIVERSITY OF CRETE   (Greece)

Author keywords

Integral membrane proteins; Lamina associated polypeptides; Nuclear lamina

Indexed keywords

LAMIN B; MEMBRANE PROTEIN; POLYPEPTIDE; PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; INTERPHASE; MEMBRANE VESICLE; MICROTUBULE; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; IMMUNOHISTOCHEMISTRY; INTERPHASE; LAMIN TYPE B; LAMINS; MEMBRANE PROTEINS; MITOSIS; MITOTIC SPINDLE APPARATUS; MOLECULAR SEQUENCE DATA; NUCLEAR ENVELOPE; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PHOSPHOPEPTIDES; PROTEIN KINASES; RATS; SEQUENCE ANALYSIS;

ANIMALIA; MAMMALIA;

EID: 0030745846     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.16.4839     Document Type: Article

References (44)

1. Aebi, U., Cohn, J. Buhle, L. and Gerace, L. (1986) The nuclear lamina is a meshwork of intermediate filaments. Nature, 323, 560-564.
2. Appelbaum, J., Blobel, G. and Georgatos, S.D. (1990) In vivo phosphorylation of the lamin B receptor. J. Biol. Chem., 265, 4181-4184.
3. Bajer, A. and Mole-Bajer, J. (1969) Formation of spindle fibers, kinetochore orientation, and behavior of the nuclear envelope during mitosis in endosperm. Chromosoma (Berl.), 27, 448-484.
4. Chaudhary, N. and Courvalin, J.-C. (1993) Stepwise reassembly of the nuclear envelope at the end of mitosis. J. Cell Biol., 112, 295-306.
5. Courvalin, J.-C., Segil, N., Blobel, G. and Worman, H.J. (1992) The lamin B receptor of the inner nuclear membrane undergoes mitosis-specific phosphorylation and is a substrate for p34cdc2-type kinase. J. Biol. Chem., 267, 19035-19038.
6. Foisner, R. and Gerace, L. (1993) Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation. Cell, 73, 1267-1279.
7. Foisner, R., Traub, P. and Wiche, G. (1991) Protein kinase A-and protein kinase C-regulated interaction of plectin with lamin B and vimentin. Proc. Natl Acad. Sci. USA, 88, 3812-3816.
8. Furukawa, K., Pante, N., Aebi, U. and Gerace, L. (1995) Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope. EMBO J., 14, 1626-1636.
9. Georgatos, S.D. (1994) Towards an understanding of nuclear morphogenesis. J. Cell. Biochem., 55, 69-76.
10. Georgatos, S.D., Meier, J. and Simos, G. (1994) Lamins and lamin-associated proteins. Curr. Opin. Cell Biol., 6, 347-353.
11. Georgatos, S.D., Pyrpasopoulou, A. and Theodoropoulos, P.A. (1997) Nuclear envelope breakdown in mammalian cells involves stepwise lamina disassembly and microtubule-driven deformation of the nuclear envelope. J. Cell Sci., in press.
12. Gerace, L. and Burke, B. (1988) Functional organization of the nuclear envelope. Annu. Rev. Cell Biol., 4, 335-374.
13. Goldberg, M.W. and Allen, T.D. (1995) Structural and functional organization of the nuclear envelope. Curr. Opin. Cell Biol., 7, 301-309.
14. Griffiths, G. (1993) Fine Structure Immunochemistry. Springer-Verlag, Berlin, Germany
15. Harris, C.A., Andryuk, P.J., Cline, S., Chan, H.K., Natarajan, A., Siekierka, J.J. and Golstein, G. (1994) Three distinct human thymopoietins are derived from alternatively spliced mRNAs. Proc. Natl Acad. Sci. USA, 91, 6283-6287.
16. Hepler, P.K. and Wolniak, S.M. (1984) Membranes in the mitotic apparatus. Their structure and function. Int. Rev. Cytol., 90, 169-238.
17. Lourim, D. and Krohne, G. (1994) Lamin-dependent nuclear envelope reassembly following mitosis: an argument. Trends Cell Biol., 4, 314-318.
18. Lourim, D., Kempf, A. and Krohne, G. (1996) Characterization and quantitation of three B-type lamins in Xenopus oocytes and eggs: increase of lamin LI protein synthesis during meiotic maturation. J. Cell Sci., 109, 1775-1785.
19. Maison, C., Horstmann, H. and Georgatos, S.D. (1993) Regulated docking of nuclear membrane vesicles to vimentin filaments during mitosis. J. Cell Biol., 123, 1491-1505.
20. Maison, C., Pyrpasopoulou, A. and Georgatos, S.D. (1995) Vimentin-associated mitotic vesicles interact with chromosomes in a lamin B-and phosphorylation-dependent manner. EMBO J., 14, 3311-3324.
21. Martin, L., Crimaudo, C. and Gerace, L. (1995) cDNA cloning and characterization of lamina-associated polypeptide 1C (LAPIC), an integral protein of the inner nuclear membrane. J. Biol. Chem., 270, 8822-8828.
22. Meier, J. and Georgatos, S.D. (1994) Type B lamins remain associated with the integral membrane protein p58 during mitosis: implications for nuclear reassembly. EMBO J., 13, 1888-1898.
23. Murray, R.G., Murray, A.S. and Pizzo, A. (1965) The fine structure of mitosis in rat thymic lymphocytes. J. Cell Biol., 26, 601-619.
24. Newport, J. and Spann, T. (1987) Disassembly of the nucleus in mitotic extracts: membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes. Cell, 48, 219-230.
25. Nigg, E.A. (1992) Assembly-disassembly of the nuclear lamina. Curr. Opin. Cell Biol., 4, 105-109.
26. Nikolakaki, E., Simos, G., Georgatos, S.D. and Giannakouros, T. (1996) Nuclear envelope associated kinase phosphorylates arginine-serine motifs and modulates interactions between the lamin B receptor and other nuclear proteins. J. Biol. Chem., 271, 8365-8372.
27. Nikolakaki, E., Meier, J., Simos, G., Georgatos, S.D. and Giannakouros, T. (1997) Mitotic phosphorylation of the lamin B receptor by a serine/ arginine kinase and p34cdc2. J. Biol. Chem., 272, 6208-6213.
28. Papamarcaki, T., Kouklis, P., Kreis, T. and Georgatos, S.D. (1991) The 'lamin B-fold'. J. Biol. Chem., 266, 21247-21251.
29. Peter, M., Nakagawa, J., Dorée, M., Labbé, J.C. and Nigg, E.A. (1990) In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell, 61, 591-602.
30. Powell, L. and Burke, B. (1990) Internuclear exchange of an inner nuclear protein (p55) in heterokaryons: in vivo evidence for the interaction of p55 with the nuclear lamina. J. Cell Biol., 111, 2225-2234.
31. Pyrpasopoulou, A., Meier, J., Maison, C. Simos, G. and Georgatos, S.D. (1996) The lamin B receptor (LBR) provides essential chromatin docking sites at the nuclear envelope. EMBO J., 15, 7108-7119.
32. Senior, A. and Gerace, L. (1988) Integral membrane proteins specific to the inner nuclear membrane and associated with the nuclear lamin. J. Cell Biol., 107, 2029-2036.
33. Simos, G. and Georgatos, S.D. (1992) The inner nuclear membrane protein p58 associates in vivo with a p58 kinase and the nuclear lamins. EMBO J., 11, 4027-4036.
34. Simos, G. and Georgatos, S.D. (1994) The lamin B receptor-associated protein p34 shares sequence homology and antigenic determinants with the splicing factor 2-associated protein p32. FEBS Lett., 346, 225-228.
35. Simos, G., Maison, C. and Georgatos, S.D. (1996) Characterization of p18, a component of the lamin B receptor complex and a new integral membrane protein of the avian erythrocyte nuclear envelope. J. Biol. Chem., 271, 12617-12625.
36. Suprynowicz, F.A. and Gerace, L. (1986) A fractionated cell-free system for analysis of prophase nuclear disassembly. J. Cell Biol., 103, 2073-2081.
37. Svitkina, T., Verkhovsky, A.B. and Borisy, G.G. (1996) Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton. J. Cell Biol., 135, 991-1007.
38. Warren, G. (1993) Membrane partitioning during cell division. Annu. Rev. Biochem., 62, 323-348.
39. Wiche, G., Becker, B., Luber, K., Weitzer, G., Castanon, M.J., Hauptmann, R., Stratowa, C. and Stewart, M. (1991) Cloning and sequencing of rat plectin indicates a 466 kDa polypeptide chain with three-domain structure based on a central alpha-helical coiled coil. J. Cell Biol., 114, 83-99.
40. Wilson, L.K. and Wiese, C. (1996) Reconstituting the nuclear envelope and endoplasmic reticulum in vitro. Semin. Cell Dev. Biol., 7, 487-496.
41. Worman, J.H., Yuan, J., Blobel, G. and Georgatos, S.D. (1988) A lamin B receptor in the nuclear envelope. Proc. Natl Acad. Sci. USA, 85, 8531-8534.
42. Worman, J.H., Evans, C.D. and Blobel, G. (1990) The lamin B receptor of the nuclear envelope inner membrane: a polytopic protein with eight potential transmembrane domains. J. Cell Biol., 111, 1535-1542.
43. Ye, Q. and Worman, H.J. (1994) Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane. J. Biol. Chem., 269, 11306-11311.
44. Ye, Q. and Worman, J.H. (1996) Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1. J. Biol. Chem., 271, 14653-14656.