Xylitol disturbs protein synthesis including the expression of HSP-70 and HSP-60, in Streptococcus mutans

Oral Microbiology and Immunology

Volumn 15, Issue 4, 2000, Pages 249-257

  Hrimech, M ^a   Mayrand, D ^b   Grenier, D ^a   Trahan, L ^a,b  

^a Groupe de Recherche en Ecologie Buccale   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

Caries; Mutans streptococci; Prevention; Stress proteins; Xylitol

Indexed keywords

BACTERIAL PROTEIN; CHAPERONIN; DNAK PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; HEAT SHOCK PROTEIN 70; PROTEIN SYNTHESIS INHIBITOR; XYLITOL;

ANTIBIOTIC RESISTANCE; ARTICLE; AUTORADIOGRAPHY; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; STREPTOCOCCUS MUTANS; WESTERN BLOTTING;

AUTORADIOGRAPHY; BACTERIAL PROTEINS; BLOTTING, WESTERN; CHAPERONIN 60; DRUG RESISTANCE, MICROBIAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI PROTEINS; GROEL PROTEIN; HSP70 HEAT-SHOCK PROTEINS; HYDROGEN-ION CONCENTRATION; PROTEIN SYNTHESIS INHIBITORS; STREPTOCOCCUS MUTANS; XYLITOL;

EID: 0033925307     PISSN: 09020055     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-302X.2000.150407.x     Document Type: Article

References (55)

1. Ang D, Liberek K, Skowyra D, Zylicz M, Georgopoulos C. Biological role and regulation of the universally conserved heat shock proteins. J Biol Chem 1991: 266: 2433-2436.
2. Ansorge W, Fast and sensitive detection of protein and DNA bands by treatment with potassium permanganate. J Biochem Biophys Methods 1985: 11: 13-20.
3. Assev S, Vegarud G, Rölla G. Growth inhibition of S'treptococcus mutans strain OMZ176 by xylitol. APMIS 1980: 88; 61-63.
4. Assev S, Wäler SM, Rölla G. Further studies on the growth inhibition on some oral bacteria by xylitol. APMIS 1983: 91: 261-265.
5. Bär A. Caries prevention with xylitol. A review of scientific evidence. World Rev Nutr Diet 1988: 55: 1-27.
6. Beckers HJA. Influence of xylitol on growth, establishment and cariogenicity of Streptococcus mutans in dental plaque of rats. Caries Res 1988: 22: 166-173.
7. Benkirane R, Gottschalk MG, Dubreuil JD. Identification of a Streptococcus suis 60-kDa heat-shock protein using Western blotting. FEMS Microbiol Lett 1997: 153: 379-385.
8. Bernhardt J, Völker U, Völker A, Antelmann H, Schmid R, Mach H et al. Specific and general stress proteins in Bacillus subtilis - a two-dimensional protein electrophoresis study. Microbiology 1997: 143: 999-1017.
9. Birkhed D. Cariological aspects of xylitol and its use in chewing gum - a review. Acta Odontol Scand 1994: 52: 1-12.
10. Brown AT, Wittenberger CL. Mannitol and sorbitol catabolism in Streptococcus mutans. Arch Oral Biol 1973: 18: 117-126.
11. Bukau B, Walker GC, Mutation altering heat shock specific subunit of RNA polymerase suppresses major cellular defects of Escherichia coli mutants lacking the DnaK chaperone. EMBO J 1990: 9: 4027-4036.
12. Carlsson J. Metabolic activities of oral bacteria. In: Thylstrup A, Fejerskov O, ed. Textbook of cariology. Copenhagen: Munksgaard, 1986: 74-100.
13. Csermely P. Stress of life: From molecules to man. Ann N Y Acad Sci 1998: 851.
14. -) strain of Streptococcus mutans from pure cultures and human saliva. Microb Ecol Health Dis 1990: 3: 113-120.
15. Foster JW. Salmonella acid shock proteins are required for the adaptive acid tolerance response. J Bacteriol 1991: 173: 6896-6902.
16. Garbe TR. Heat shock proteins and infection: interactions of pathogen and host. Experientia 1992: 48: 635-639.
17. Gauthier L, Vadeboncoeur C, Mayrand D. Loss of sensibility to xylitol by Streptococcus mutans LG-1. Caries Res 1984: 18: 289-295.
18. Gething MJ, Sambrook J. Protein folding in the cell. Nature 1992: 355: 33-44.
19. Hamel JMD, Brodeur BD. Heat shock response of Streptococcus pneumoniae: identification of immunoreactive stress proteins. Microb Pathog 1997: 23: 11-21.
20. Hardie JM, Bowden GH. Physiological classification of oral viridans streptococci. J Dent Res 1976: 55: 166-176.
21. Heyde M, Portaller R. Acid shock proteins of Escherichia coli. FEMS Microbiol Lett 1990: 57: 19-26.
22. Jayaraman GC, Burne RA. DnaK expression in response to heat shock of Streptococcus mutons. FEMS Microbiol Lett 1995: 131: 255-261.
23. Jayaraman GC, Penders JE, Burne RA. Transcriptional analysis of the Streptococcus mutans hrcA, grpE, and dnaK genes and regulation of expression in response to heat shock and environmental acidification. Mol Microbiol 1997: 25: 329-341.
24. Jenkens DE, Auger EA, Martin A. Role of RpoH, a heat shock regulation protein, in Escherichia coli carbon starvation and survival. J Bacteriol 1991: 173: 1992-1996.
25. Jenkens DE, Chaison SA, Martin A. Starvation-induced cross protection against osmotic challenge in Escherichia coli. J Bacteriol 1990: 172: 2779-2781.
26. 2 challenge in Escherichia coli. J Bacteriol 1988: 170: 3910-3914.
27. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970: 227: 680-685.
28. Lehner T, Lavery E, Smith R, van der Zee R, Mizushima Y, Shinnick T. Association between the 65-kilodalton heat shock protein, Streptococcus sanguis, and the corresponding antibodies in Behçet's syndrome. Infect Immun 1991: 59: 1434-1441.
29. Lindquist S, Craig EA. The heat shock proteins. Annu Rev Genet 1988: 22: 631-677.
30. Loesche WJ. Role of Streptococcus mutans in human dental decay. Microbiol Rev 1986: 50: 353-380.
31. Lorimer GH, Baldwin TO, ed. Molecular chaperones. Methods Enzymol 1998: 290: 1-563.
32. Mäkinen KK. Possible mechanisms for the cariostatic effect of xylitol. In: Ritzel G, Brubacher G, ed. Monosaccharides and polyalcohols in nutrition, therapy and dietetics. Berne: Huber, 1976: 368-380.
33. Mäkinen KK. Biochemical principles of the use of xylitol in medicine and nutrition with special consideration of dental aspects. Experientia 1978: 30 (suppl): 7-160.
34. Mäkinen KK. Latest dental studies on xylitol and mechanism of action of xylitol in caries limitation. In: Grenby T, ed. Progress in sweeteners. London: Elsevier, 1989: 331-362.
35. Mäkinen KK, Isokangas P. Relationship between carbohydrate sweeteners and oral diseases. Prog Food Nutr Sci 1988: 12: 73-109.
36. Morange M. Les molécules chaperons. Recherche 1993: 259: 1238-1245.
37. Peterson GL. Determination of total protein. Methods Enzymol 1981: 91: 95-119.
38. Rogers AH, Pilowsky KA, Zilm PS, Gully NJ. Effects of pulsing with xylitol on mixed continuous cultures of oral streptococci. Aust Dent J 1991: 36: 231-235.
39. Scheinin A. Le xylitol, sucre de substitution cariostatique. Actualité Odontol Stomatol 1987: 158: 213-222.
40. Söderling E, Isokangas P, Tenovuo J, Mustakallio S, Mäkinen KK. Long-term xylitol consumption and mutans streptococci in plaque. Caries Res 1991: 25: 153-157.
41. Söderling E, Mäkinen KK, Chen CY, Pape HR, Loesche W, Mäkinen PL. Effect of sorbitol, xylitol, and xylitol/sorbitol chewing gum on dental plaque. Caries Res 1989: 23: 378-384.
42. Spence JAC, Georgopoulos C. Role of Escherichia coli heat shock proteins DnaK and HtpG (C62.5) in response to nutritional deprivation. J Bacteriol 1990: 172: 7157-7166.
43. Taglicht D, Padan A, Oppenheim B, Schuldiner S. An alkaline shift induces the heat shock response in Escherichia coli. J Bacteriol 1987: 169: 885-887.
44. Terleckyj B, Willette NP, Shockman GD. Growth of several cariogenic strains of streptococci in a chemically defined medium. Infect Immun 1975: 11: 649-655.
45. Trahan L. Xylitol: a review of its action on mutans streptococci and dental plaque - its clinical significance. Int Dent J 1995: 45: 77-92.
46. Trahan L, Bareil M, Gauthier L, Vadeboncoeur C. Transport and phosphorylation of xylitol by a fructose phosphotransferase system in Streptococcus mutans. Caries Res 1985: 19: 53-63.
47. -) mutants from human isolates of mutans streptococci during growth on dietary sugars in the presence of xylitol. J Dent Res 1996: 75: 1892-1900.
48. Trahan L, Mouton C. Selection for Streptococcus mutans with an altered xylitol transport capacity in chronic xylitol consumers. J Dent Res 1987: 66: 982-988.
49. Trahan L, Néron S, Bareil M. Intracellular xylitol-phosphate hydrolysis and efflux of xylitol in Streptococcus sobrinus. Oral Microbiol Immunol 1991: 6: 41-50.
50. Trahan L, Söderling E, Dréan M-F, Chevrier M-C. Effect of xylitol consumption on the plaque-saliva distribution of mutans streptococci and the occurrence and long-term survival of xylitol-resistant strains. J Dent Res 1992: 71: 1785-1791.
51. Vadeboncoeur C, Trahan L. Comparative study of Streptococcus mutans laboratory strains and fresh isolates from carious and caries-free tooth surfaces and from subjects with hereditary fructose intolerance. Infect Immun 1983: 40: 81-90.
52. Vadeboncoeur C, Trahan L, Mouton C, Mayrand D. Effect of xylitol on the growth and glycolysis of acidogenic oral bacteria. J Dent Res 1983: 2: 882-884.
53. van Eden W, Young DB. Stress proteins in medicine. New York: Marcel Dekker, 1996.
54. van Houte J. Role of microorganisms in caries etiology. J Dent Res 1994: 73: 672-681.
55. Young D, Roman E, Moreno C, O'Brien R, Born W. Molecular chaperones and the immune response. Phil Trans R Soc Lond B 1993: 339: 363-368.