Co-occurrence of non-toxic (Cyanopeptolin) and toxic (Microcystin) peptides in a bloom of Microcystis sp. fuom a Chilean lake

Systematic and Applied Microbiology

Volumn 23, Issue 2, 2000, Pages 191-197

  Neumann, Uwe ^a   Campos, Victoriano ^b   Cantarero, Sergio ^b   Urrutia, Homero ^c   Heinze, Rita ^d   Weckesser, Jürgen ^a   Erhard, Marcel ^e  

^a UNIVERSITY OF FREIBURG   (Germany)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO   (Chile)

^c UNIVERSITY OF CONCEPCIÓN   (Chile)

^d UMWELTBUNDESAMT   (Germany)

^e Biotechnologiepark Luckenwalde   (Germany)

Author keywords

Bloom; Chile; Cyanobacteria; Cyanopeptolin; Enzyme inhibition; MALDI TOF; Microcystin; Microcystis; Peptides

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL TOXIN; CYANOGINOSIN; CYANOPEPTOLIN; ELASTASE; GLUTATHIONE TRANSFERASE; PAPAIN; PHOSPHOPROTEIN PHOSPHATASE 1; PLASMIN; PROTEIN KINASE; SERINE PROTEINASE; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; CHILE; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; LAKE; MASS SPECTROMETRY; MICROCYSTIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEASONAL VARIATION;

BACTERIA (MICROORGANISMS); CYANOBACTERIA; MICROCYSTIS; MICROCYSTIS SP.;

EID: 0033924249     PISSN: 07232020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0723-2020(00)80004-1     Document Type: Article

References (36)

1. AN, J.S.; CARMICHAEL, W.W.: Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins. Toxicon 32: 1495-1507 (1994)
2. AZEVEDO, S. M. F. O, EVANS, W. R, CARMICHAEL, W. W, NAMIKOSHI, M.: First report of microcystin from a Brazilian isolate of the cyanobacterium Microcystis aeruginosa. J. Appl. Phycol. 6: 261-265 (1994).
3. BARRETT, A.J.: Cystatin, the egg white inhihitor of cysteine proteinases. Meth. Enzym. 80: 771-778 (1981).
4. BIETH, J.; SPIESS, B.; WERMUTH, C.G.: The synthesis and analytical use of a highly sensitive and convenient substrate of elastase. Biochem. Med. 11: 350-357 (1974).
5. BIRK, I.M.; DIERSTEIN, R.; KAISER, I.; MATERN, U.; KÖNIG G.; W.A.; KREBBER, R.; WECKESSER, J.: Nontoxic and toxic oligopeptides with D-amino acids and unusual residues in Microcystis aeruginosa PCC 7806. Arch. Microbiol. 151: 411-415 (1989).
6. CAMPOS, V.; CANTARERO, S.; URRUTIA, H.; HEINZE, R.; WIRSING, B.; NEUMANN, U.; WECKESSER, J.: Microcystin in cyanobacterial blooms in a chilean lake. Syst. Appl. Microbiol. 22: 169-173 (1999).
7. CARMICHAEL, W.W.: The toxins of cyanobacteria. Scient. Amer. 270: 64-72 (1994).
8. CHU, F.S.; X. HUANG, R.D. WEI, CARMICHAEL, W.W.: Production and characterization of antibodies against microcystins. Appl. Environ. Microbiol. 55: 1928-1933 (1989).
9. COOK, P.F.; NEVILLE, JR. M.E.; VRANA, K.E.; HARTL, F.T.; ROSKOSKI, JR. R.: Adenosine cyclic 3′,5′monophosphate dependent protein kinase: kinetic mechanism for the bovine skeletal catalytic subunit. Biochem. 21: 5794-5799 (1982).
10. 3H]methyltrienolon. Biochem. J. 288: 361-367 (1992).
11. DITTMANN, E.; NEILAN, B.A.; ERHARD, M.; VON DÖHREN H.; BÖRNER, T.: Insertional mutagenesis of a peptide synthetase gene that is responsible for hepatotoxin production in the cyanobacterium Microcystis aeruginosa PCC 7806. Mol. Microbiol. 26: 779-787 (1997).
12. ELFANT, M.; BRYANT L.; STARCHER, B.: Isolation and characterization of a proteinase inhibitor from marama beans (42184). Proc. Soc. Exp. Biol. Med. 180: 329-333 (1985).
13. ERHARD, M.; VON DÖHREN, H.; JUNGBLUT, P.: Rapid typing and elucidation of new secondary metabolites of intact cyanobacteria using MALDI-TOF mass spectrometry. Nature Biotech. 15: 906-909 (1997).
14. ERHARD, M.: Matrix Assisted Laser Desorption/Ionisation -Time of Flight Massen-spektrometrie von Cyanobakterien und Untersuchungen zur Biosynthese und Funktion der Microcystine. Thesis, Technische Universität Berlin (1999).
15. FALCONER, I. R. Algal toxins and human helath. In: The Handbook of Environmental Chemistry Vol 5, part C, Quality and Teatment of Drinking Water II (ed. by J. Hrubec), pp. 53-82. Springer-Verlag Berlin Heidelberg (1998).
16. JAKOBI, C.; OBERER, L.; QUIQUEREZ, C.; KÖNIG, W.A.; WECKESSER, J.: Cyanopeptolin S, a sulphate containing depsipeptide from a water bloom of Microcystis sp. FEMS Microbiol. Lett. 129: 129-134 (1995).
17. JAKOBI, C.; RINEHART, K.L. CODD, G.A.; CARMIENKE, I.; WECKESSER, J.: Occurrence of toxic water blooms containing microcystins in a German lake over a three year period. J. Syst. Appl. Microbiol. 19: 249-254 (1996a).
18. JAKOBI, C.; RINEHART, K.L.; NEUBER, R.; MEZ, K.; WECKESSER, J.: Cyanopeptolin SS, a disulfated depsipeptide from a water bloom in Leipzig (Germany): structural elucidation and biological activities. Phycologia 35: 111-116 (1996b).
19. HABIG, W.H.; PABST, M.J.; JAKOBY W.B.: Glutathione S-transferase. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249: 7130-7139 (1974).
20. LAWTON, L. A.; EDWARDS, C.; CODD, G. A.: Extraction and high-performance liquid chromatographic method for the determination of microcystins in raw and treated waters. Analyst 119: 1525-1530 (1994).
21. LOPEZ, M.F.; PATTON, W.F.; SAWLICH, W.B.; ERDJUMENT-BROMAGE, H.; BARRY, P.; GMYREK, K.; HINES, T, TEMPST, P, SKEA, W.M.: A glutathione S-transferase (GST) isozyme from broccoli with significant sequence homology to the mammalian theta-class of GSTs. Biochim. Biophys. Acta 1205: 29-38 (1994).
22. LOTTENBERG, R.; CHRISTENSEN, U.; JACKSON, C.M.; AND COLEMAN, P.L.: Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates. Meth. Enzym. 80: 341-361 (1981).
23. MARTIN, C.; OBERER, L.; INO, T.; KÖNIG;, W.A.; BUSCH, M.; WECKESSER., J.: Cyanopeptolins, new depsipeptides from the cyanobacterium Microcystis sp. PCC 7806. J. Antibiot. 46: 1550-1556 (1993).
24. MOORE, R.E.: Cyclic peptides and depsipeptides from cyanobacteria: a review. J. Ind. Microbiol. Biotech. 16: 134-143 (1996).
25. NAMIKOSHI, M.; RINEHART, K.L.: Bioactive compounds produced by cyanobacteria. J. Ind. Microbiol. Biotech. 17: 373-384 (1996).
26. NEUMANN, U.; FORCHERT, A.; FLURY, T.; WECKESSER, J.: Microginin FR1, a linear peptide from a water bloom of Microcystis sp. FEMS Microbiol. Lett. 153: 475-478 (1997).
27. OKINO, T.; MURAKAMI, M.; HARAGUCHI, R.; MUNEKATA, H.; MATSUDA, H.; YAMAGUCHI, K.: Micropeptins A and B, plasmin and trypsin inhibitors from the blue-green alga Microcystis aeruginosa. Tetrahedron Lett. 34: 8131-8134 (1993).
28. PILETTE, J.F.; XO, Y.C.; FAN, T.S.; SKOCZENSKI, B.A.; CHU, F.S.; HUANG, X.: The detection of microcystins (algal hepatotoxins) in water by enzyme immunoassay. In: O. Moestrup (Ed). First International Congress on Toxic Cyanobacteria, 21.-24. August 1995, Ronne, Denmark (1995).
29. RINEHART, K.L.; NAMIKOSHI, M.; CHOI, B.W.: Structure and biosynthesis of toxins from blue-green algae (cyanobacteria). J. Appl. Phycol. 6: 159-176 (1994)
30. SCARAFIA, M. E.; AGNESE, A. M.; CABRERA, J. L.: Microcystis aeruginosa: behaviour and toxic features in San Roque dam (Argentina). Nat. Toxins 3: 75-77 (1995).
31. SHI, L.; CARMICHAEL, W.W.; MILLER, I.: Immuno-gold localization of hepatotoxins in cyanobacterial cells Arch. Microbiol. 163: 7-15 (1995).
32. TSUKAMOTO, S.; PAINULY, P.; YOUNG, K.A.; YANG, X.; SHIMIZU, Y.; CORNEIL, L.: Microcystilide A: a novel cell-differentiation-promoting depsipeptide from Microcystis aeruginosa NO-15-1840. J. Am. Chem. Soc. 115: 11046-11047 (1993).
33. WATANABE, M.F.; HARADA, K.; CARMICHAEL, W.W.; FUJIKI, H.: Toxic Microcystis. CRC-Press, Boca Raton, Florida (USA), (1996).
34. WECKESSER, J.; MARTIN, C.; JAKOBI, C.: Depsipeptides from cyanobacteria: structures and biological activities. J. Syst. Appl. Microbiol. 19: 133-138 (1996).
35. WIRSING, B.; FLURY, T.; WIEDNER, C.; NEUMANN, U.; WECKESSER, J.: Estimation of the microcystin content in field samples from German lakes using the colorimetric protein-phosphatase inhibition assay and RP-HPLC. Environ. Tox. Water Qual. 14: 23-29 (1999).
36. ZUÑIGA, L.R.; CARVAJAL, M.A.: Cyanobacterial blooms in lake Peñuelas, adrinking water reservoir. Proceedings, II. Biennial Water Quality Symposium. Aug. 1990, Viña del Mar/Chile, pp. 297-301 (1990).