Laser-polarized 3He as a probe for dynamic regional measurements of lung perfusion and ventilation using magnetic resonance imaging

Magnetic Resonance in Medicine

Volumn 44, Issue 1, 2000, Pages 1-4

  Viallon, Magalie ^a   Berthezène, Yves ^b   Décorps, Michel ^c   Wiart, Marlène ^b   Callot, Virginie ^a   Bourgeois, Marc ^a   Humblot, Hubert ^d   Briguet, André ^a   Crémillieux, Yannick ^a,e  

^a UNIVERSITÉ LYON 1   (France)

^b LOUIS PRADEL HOSPITAL   (France)

^c GRENOBLE UNIVERSITY HOSPITAL   (France)

^d INSTITUT LAUE LANGEVIN   (France)

^e UNIVERSITÉ DE LYON   (France)

Author keywords

Hyperpolarized gas; Lung MRI; Pulmonary blood volume map; Ventilation perfusion

Indexed keywords

BIOLOGICAL ORGANS; BLOOD; DISEASES; HEMODYNAMICS; INERT GASES; MAGNETISM; PROBES; RESONANCE;

BLOOD VOLUMES; EXPERIMENTAL ANIMALS; HYPERPOLARIZED; INHOMOGENEOUS STRUCTURE; LUNG MRIS; MAGNETIC RESONANCE PERFUSIONS; PATHOLOGICAL CONDITIONS; PULMONARY VENTILATION;

MAGNETIC RESONANCE IMAGING;

HELIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; LASER; LUNG BLOOD VOLUME; LUNG EMBOLISM; LUNG VENTILATION PERFUSION RATIO; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RADIOFREQUENCY; RAT;

EID: 0033923377     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/1522-2594(200007)44:1<1::AID-MRM1>3.0.CO;2-U     Document Type: Article

References (25)

1. 129Xe. Nature 1994;370:199-201.
2. Middleton H, Black RD, Saam B, Cates GD, Cofer GP, Guenther R, Happer W, Hedlund LW, Johnson GA, Juvan K, Swartz J. MR imaging with hyperpolarized 3He gas. Magn Reson Med 1995;33:271-275.
3. Ebort M, Grossmann T, Heil W, Otten EW, Surkau R, Leduc M, Bachert P, Knopp MV, Schad LR, Thelen M. Nuclear magnetic resonance imaging with hyperpolarized Helium-3. Lancet 1996;347:1297-1299.
4. Alderson PO, Martin EC. Pulmonary embolism: diagnosis with multiple imaging modalities. Radiology 1987;164:297-312.
5. Berthezène Y, Vexler V, Clément O, Mühlor A, Moseley ME, Brasch RC. Contrast-enhanced MR imaging of the lung: assessments of ventilation and perfusion. Radiology 1992;183:667-672.
6. Hatabu H, Gaa J, Kim D, Li W, Prasad PV, Edelman RR. Pulmonary perfusion: qualitative assessment with dynamic contrast-enhanced MRI using ultra-short TE and inversion recovery Turbo FLASH. Magn Reson Med 1996;36:503-508.
7. Mai VM, Berr SS. MR perfusion imaging of pulmonary parenchyma using pulsed arterial spin labeling techniques: FAIRER and FAIR. J Magn Reson Imag 1999;9:483-487.
8. Cutillo AG, editor. Application of magnetic resonance to the study of lung. Armonk, NY: Futura Publishing Company; 1996. p 187.
9. Colegrove FD, Schearer LD, Walters GK. Polarization of 3He gas by optical pumping. Phys Rev 1963;132:2561-2572.
10. Becker J, Heil W, Krug B. Study of mechanical compression of spin-polarized 3He gas. Nucl Instrum Methods 1994:A346:45-51.
11. Pochon S, Hyacinthe R, Terrettaz J, Robert F, Schneider M, Tournier H. Long circulating superparamagnetic particles with high T2 relaxivity. Ada Radiologica 1997;38(suppl. 412):69-72.
12. Crémillieux Y, Berthezène Y, Humblot H, Viallon M, Canet E, Bourgeois M, Albert T, Heil W, Briguet A. A combined 1H perfusion/3He ventilation NMR study in rat lungs. Magn Reson Med 1999;41:645-648.
13. Ahn CB, Kim JH, Cho ZH. High speed spiral-scan echo planar NMR imaging. IEEE 1986; MI-5,1:2-7.
14. Meyer CH, Hu BS, Nishimura DG, Macovski A. Fast coronary artery imaging. Magn Reson Med 1992;28:202-213.
15. Ruppert K, Brookeman JR, Mugler JP. Real time MR imaging of pulmonary gas-flow dynamics with hyperpolarized He3. In: Proceedings of the 6th Annual Meeting of the ISMRM, Sydney, 1998. p 1909.
16. Johnson GA, Cates GD, Chen XJ, Cofer GP, Driehuys B, Happer W. Hedlund LW, Saam B, Shattuck MD. Dynamics of magnetization in hyporpolarized gas MRI of the lungs. Magn Reson Med 1997;38:66-71.
17. Möller HE, Chen XJ, Chawla MS, Driehuys B, Hedlund LW, Johnson GA. Signal dynamics in magnetic resonance imaging of the lung with hyperpolarized gases. J Magn Reson 1998;135:133-143.
18. Majumdar S, Gore JC. Studies of diffusion in random fields produced by variations in susceptibility. J Magn Reson 1988;78:41-55.
19. Ogawa S, Lee T, Nayak AS, Glynn P. Oxygenation-sensitive contrast in Magnetic Resonance Image of rodent brain at high magnetic fields. Magn Reson Med 1990;14:68-78.
20. Villringer A, Rosen BR, Belliveau JW, Ackerman JL, Lauffer RB, Buxton RB, Chao Y, Wedeen VJ, Brady TJ. Dynamic imaging with lanthanide chelates in normal brain: contrast due to magnetic susceptibility effects. J Magn Reson 1988;78:41-55.
21. Rosen BR, Belliveau JW, Vevea JM, Brady TJ. Perfusion imaging with NMR contrast agent. Magn Reson Med 1990;14:249-265.
22. Axel L. Methods using blood pool tracers. In: Le Bihan D, editor. Diffusion and perfusion magnetic resonance imaging. New York: Raven Press; 1995. p 205-211.
23. Caramia F, Aronenn HJ, Sorensen AG, Belliveau JW, Gonzalez RG, Rosen BR. Perfusion MR imaging with exogenous contrast agents. In: Le Bihan D, editor. Diffusion and perfusion magnetic resonance imaging. New York: Raven Press; 1995. p 255-207.
24. Ostergaard L, Weisskopf RM, Chesler DA, Gyldensted C, Rosen BR. High resolution measurement of rCBF using intravascular tracer bolus passages. Part 1: Mathematical approach and statistical analysis. Magn Reson Med 1996;36:715-725.
25. 2. Magn Reson Med 1999;42:729-737.