메뉴 건너뛰기




Volumn 30, Issue 6, 2000, Pages 565-574

Identification of enzymes responsible for rifalazil metabolism in human liver microsomes

Author keywords

[No Author keywords available]

Indexed keywords

4 CHLOROMERCURIBENZOIC ACID; 4 NITROPHENYL PHOSPHATE; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); ASTEMIZOLE; AZITHROMYCIN; CLARITHROMYCIN; CLOFAZIMINE; CYCLOSPORIN A; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; DYFLOS; ESTERASE; ESTERASE INHIBITOR; FLUCONAZOLE; KETOCONAZOLE; LORATADINE; MICONAZOLE; MIDAZOLAM; NEOSTIGMINE; NIFEDIPINE; PHYSOSTIGMINE; RIFALAZIL; TROLEANDOMYCIN; UNCLASSIFIED DRUG;

EID: 0033922469     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982500406408     Document Type: Article
Times cited : (18)

References (34)
  • 1
    • 0343193275 scopus 로고
    • Serum esterases: Two types of esterase (A and B) hydrolysing p-nitrophenyl acetate, propionate and butyrate, and a method for their determination
    • ALDRIDGE, W. N., 1953, Serum esterases: two types of esterase (A and B) hydrolysing p-nitrophenyl acetate, propionate and butyrate, and a method for their determination. Biochemical Journal, 53, 110-117.
    • (1953) Biochemical Journal , vol.53 , pp. 110-117
    • Aldridge, W.N.1
  • 3
    • 0027971263 scopus 로고
    • Activity of KRM-1648 alone or in combination with ethambutol or clarithromycin against Mycobacterium avium in beige mouse model of disseminated infection
    • BERMUDEZ, L. E., KOLONOSKI, P., YOUNG, L. S. and INDERLIED, C. B., 1994, Activity of KRM-1648 alone or in combination with ethambutol or clarithromycin against Mycobacterium avium in beige mouse model of disseminated infection. Antimicrobial Agents and Chemotherapys, 38, 1844-1848.
    • (1994) Antimicrobial Agents and Chemotherapys , vol.38 , pp. 1844-1848
    • Bermudez, L.E.1    Kolonoski, P.2    Young, L.S.3    Inderlied, C.B.4
  • 5
    • 0028352117 scopus 로고
    • In vitro and in vivo antibacterial activities of KRM-1648 and KRM-1657, new rifamycin derivatives
    • FUJH, K., TSUJI, A., MIYAZAKI, S., YAMAGUCHI, K. and GOTO, S., 1994, In vitro and in vivo antibacterial activities of KRM-1648 and KRM-1657, new rifamycin derivatives. Antimicrobial Agents and Chemotherapy, 38, 1118-1122.
    • (1994) Antimicrobial Agents and Chemotherapy , vol.38 , pp. 1118-1122
    • Fujh, K.1    Tsuji, A.2    Miyazaki, S.3    Yamaguchi, K.4    Goto, S.5
  • 8
    • 0029872462 scopus 로고    scopus 로고
    • Identification and antimicrobial activity of urinary metabolites of a rifamycin derivative in dog
    • HOSOE, K., MAE, T., YAMASHITA, K., FUJH, K., YAMANE, T., HIDAKA, T. and OHASI, T., 1996b, Identification and antimicrobial activity of urinary metabolites of a rifamycin derivative in dog. Xenobiotica, 26, 321-332.
    • (1996) Xenobiotica , vol.26 , pp. 321-332
    • Hosoe, K.1    Mae, T.2    Yamashita, K.3    Fujh, K.4    Yamane, T.5    Hidaka, T.6    Ohasi, T.7
  • 9
    • 0030903839 scopus 로고    scopus 로고
    • Metabolism of rifabutin in human enterocyte and liver microsomes: Kinetic parameters, identification of enzyme systems, and drug interactions with macrolides and antifungal agents
    • IATSIMIRSKAIA, E., TULEBAEV, S., STOROZHUK, E., UTKIN, I., SMITH, D., GERBER, N. and KOUDRIAKOVA, T., 1997, Metabolism of rifabutin in human enterocyte and liver microsomes: kinetic parameters, identification of enzyme systems, and drug interactions with macrolides and antifungal agents. Clinical Pharmacology and Therapeutics, 61, 554-562.
    • (1997) Clinical Pharmacology and Therapeutics , vol.61 , pp. 554-562
    • Iatsimirskaia, E.1    Tulebaev, S.2    Storozhuk, E.3    Utkin, I.4    Smith, D.5    Gerber, N.6    Koudriakova, T.7
  • 10
    • 0031455260 scopus 로고    scopus 로고
    • HIV protease inhibitors, saquinavir, indinavir and ritonavir: Inhibition of CYP3A4-mediated metabolism of testosterone and benzoxazinorifamycin, KRM-1648, in human liver microsomes
    • INABA, T., FISCHER, N. E., RIDDICK, D. S., STEWART, D. J. and HIDAKA, T., 1997, HIV protease inhibitors, saquinavir, indinavir and ritonavir: inhibition of CYP3A4-mediated metabolism of testosterone and benzoxazinorifamycin, KRM-1648, in human liver microsomes. Toxicology Letters, 93, 215-219.
    • (1997) Toxicology Letters , vol.93 , pp. 215-219
    • Inaba, T.1    Fischer, N.E.2    Riddick, D.S.3    Stewart, D.J.4    Hidaka, T.5
  • 11
    • 0028114141 scopus 로고
    • Activity of the benzoxazinorifamycin KRM-1648 against the Mycobacterium avium complex in vitro and in macrophages
    • INDERLIED, C. B., BARBARA-BURNHAM, L., WU, M., YOUNG, L. and BERMUDEZ, L. E., 1994, Activity of the benzoxazinorifamycin KRM-1648 against the Mycobacterium avium complex in vitro and in macrophages. Antimicrobial Agents and Chemotherapy, 38, 1838-1843.
    • (1994) Antimicrobial Agents and Chemotherapy , vol.38 , pp. 1838-1843
    • Inderlied, C.B.1    Barbara-Burnham, L.2    Wu, M.3    Young, L.4    Bermudez, L.E.5
  • 12
    • 0030764254 scopus 로고    scopus 로고
    • Rifampicin and rifabutin and their metabolism by human liver esterases
    • JAMIS-DOW, C. A., KATKI, A. G., COLLINS, J. M. and KLECKER, R. W., 1997, Rifampicin and rifabutin and their metabolism by human liver esterases. Xenobiotica, 27, 1015-1024.
    • (1997) Xenobiotica , vol.27 , pp. 1015-1024
    • Jamis-Dow, C.A.1    Katki, A.G.2    Collins, J.M.3    Klecker, R.W.4
  • 13
    • 0029829728 scopus 로고    scopus 로고
    • Low-dose aerosol infection model for testing drugs for efficacy against Mycobacterium tuberculosis
    • KELLY, B. P., FURNEY, S. K., JESSEN, M. T. and ORME, I. M., 1996, Low-dose aerosol infection model for testing drugs for efficacy against Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy, 40, 2809-2812.
    • (1996) Antimicrobial Agents and Chemotherapy , vol.40 , pp. 2809-2812
    • Kelly, B.P.1    Furney, S.K.2    Jessen, M.T.3    Orme, I.M.4
  • 14
    • 0028093427 scopus 로고
    • Activity of KRM-1648, a new benzoxazinorifamycin, against Mycobacterium tuberculosis in a murine model
    • KLEMENS, S. P., GROSSI, M. A. and CYNAMON, M. H., 1994, Activity of KRM-1648, a new benzoxazinorifamycin, against Mycobacterium tuberculosis in a murine model. Antimicrobial Agents and Chemotherapy, 38, 2245-2248.
    • (1994) Antimicrobial Agents and Chemotherapy , vol.38 , pp. 2245-2248
    • Klemens, S.P.1    Grossi, M.A.2    Cynamon, M.H.3
  • 15
    • 0028835430 scopus 로고
    • In vitro activity of the benzoxazinorifamycin KRM-1648 against drug-susceptible and multidrug-resistant tubercle bacilli
    • LUNA-HERRERA, J., REDDY, M. V. and GANGADHARAM, P. R. J., 1995, In vitro activity of the benzoxazinorifamycin KRM-1648 against drug-susceptible and multidrug-resistant tubercle bacilli. Antimicrobial Agents and Chemotherapy, 39, 440-444.
    • (1995) Antimicrobial Agents and Chemotherapy , vol.39 , pp. 440-444
    • Luna-Herrera, J.1    Reddy, M.V.2    Gangadharam, P.R.J.3
  • 16
    • 0029822605 scopus 로고    scopus 로고
    • In vitro metabolism of a rifamycin derivative by animal and human liver microsomes, whole blood and expressed human CYP3A isoform
    • MAE, T., HOSOE, K., FUJH, K., YAMASHITA, K., YAMANE, T., HIDAKA, T. and OHASHI, T., 1996, In vitro metabolism of a rifamycin derivative by animal and human liver microsomes, whole blood and expressed human CYP3A isoform. Xenobiotica, 26, 793-802.
    • (1996) Xenobiotica , vol.26 , pp. 793-802
    • Mae, T.1    Hosoe, K.2    Fujh, K.3    Yamashita, K.4    Yamane, T.5    Hidaka, T.6    Ohashi, T.7
  • 17
    • 0031691174 scopus 로고    scopus 로고
    • Effect of a new rifamycin derivative, rifalazil, on liver microsomal enzyme induction in rat and dog
    • MAE, T., HOSOE, K., YAMAMOTO, T., HIDAKA, T., OHASHI, T., KLEEMAN, J. M. and ADAMS, P. E., 1998, Effect of a new rifamycin derivative, rifalazil, on liver microsomal enzyme induction in rat and dog. Xenobiotica, 28, 759-766.
    • (1998) Xenobiotica , vol.28 , pp. 759-766
    • Mae, T.1    Hosoe, K.2    Yamamoto, T.3    Hidaka, T.4    Ohashi, T.5    Kleeman, J.M.6    Adams, P.E.7
  • 18
    • 0032693695 scopus 로고    scopus 로고
    • Isolation and identification of major metabolites of rifalazil in mouse and human
    • MAE, T., KONISHI, E., HOSOE, K. and HIDAKA, T., 1999, Isolation and identification of major metabolites of rifalazil in mouse and human. Xenobiotica, 29, 1073-1087.
    • (1999) Xenobiotica , vol.29 , pp. 1073-1087
    • Mae, T.1    Konishi, E.2    Hosoe, K.3    Hidaka, T.4
  • 19
    • 0029861539 scopus 로고    scopus 로고
    • Comparative antimycobacterial activities of rifampin, rifapentine, and KRM-1648 against a collection of rifampin-resistant Mycobacterium tuberculosis isolates with known rpoB mutations
    • MOGHAZEH, S. L., PAN, X., ARAIN, T., STOVER, C. K., MUSSER, J. M. and KREISWIRTH, B. N., 1996, Comparative antimycobacterial activities of rifampin, rifapentine, and KRM-1648 against a collection of rifampin-resistant Mycobacterium tuberculosis isolates with known rpoB mutations. Antimicrobial Agents and Chemotherapy, 40, 2655-2657.
    • (1996) Antimicrobial Agents and Chemotherapy , vol.40 , pp. 2655-2657
    • Moghazeh, S.L.1    Pan, X.2    Arain, T.3    Stover, C.K.4    Musser, J.M.5    Kreiswirth, B.N.6
  • 20
    • 0029950710 scopus 로고    scopus 로고
    • Bacteriostatic and bactericidal activities of benzoxazinorifamycin KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium in human macrophages
    • MOR, N., SIMON, B. and HEIFETS, L., 1996, Bacteriostatic and bactericidal activities of benzoxazinorifamycin KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium in human macrophages. Antimicrobial Agents and Chemotherapy, 40, 1482-1485.
    • (1996) Antimicrobial Agents and Chemotherapy , vol.40 , pp. 1482-1485
    • Mor, N.1    Simon, B.2    Heifets, L.3
  • 22
    • 0029881154 scopus 로고    scopus 로고
    • Chemotherapeutic activity of benzoxazinorifamycin, KRM-1648, against Mycobacterium tuberculosis in C57BL/6 mice
    • REDDY, M. V., LUNA-HERRERA, J., DANELUZZI, D. and GANGADHARAM, P. R., 1996, Chemotherapeutic activity of benzoxazinorifamycin, KRM-1648, against Mycobacterium tuberculosis in C57BL/6 mice. Tubercle and Lung Disease, 77, 154-159.
    • (1996) Tubercle and Lung Disease , vol.77 , pp. 154-159
    • Reddy, M.V.1    Luna-Herrera, J.2    Daneluzzi, D.3    Gangadharam, P.R.4
  • 25
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • SHIMADA, T., YAMAZAKI, H., MIMURA, M., INUI, Y. and GUENGERICH, F. P., 1994, Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. Journal of Pharmacology and Experimental Therapeutics, 270, 414-423.
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 26
    • 0033610010 scopus 로고    scopus 로고
    • Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver
    • SUMIDA, A., KINOSHITA, K., FUKUDA, T., MATSUDA, H., YAMAMOTO, I., INABA, T. and AZUMA, J., 1999, Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver. Biochemical and Biophysical Research Communications, 262, 499-503.
    • (1999) Biochemical and Biophysical Research Communications , vol.262 , pp. 499-503
    • Sumida, A.1    Kinoshita, K.2    Fukuda, T.3    Matsuda, H.4    Yamamoto, I.5    Inaba, T.6    Azuma, J.7
  • 27
    • 0027446212 scopus 로고
    • In vitro antimicrobial activity of benzoxazinorifamycin, KRM-1648, against Mycobacterium avium complex determined by the radiometric method
    • TOMIOKA, H., SAITO, H., FUJH, K., SATO, K. and HIDAKA, T., 1993, In vitro antimicrobial activity of benzoxazinorifamycin, KRM-1648, against Mycobacterium avium complex determined by the radiometric method. Antimicrobial Agents and Chemotherapy, 37, 67-70.
    • (1993) Antimicrobial Agents and Chemotherapy , vol.37 , pp. 67-70
    • Tomioka, H.1    Saito, H.2    Fujh, K.3    Sato, K.4    Hidaka, T.5
  • 28
    • 0026515252 scopus 로고
    • Chemotherapeutic efficacy of a newly synthesized benzoxazinorifamycin, KRM-1648, against Mycobacterium avium complex infection induced in mice
    • TOMIOKA, H., SAITO, H., SATO, K., YAMANE, T., YAMASHITA, K., HOSOE, K., FUJH, K. and HIDAKA, T., 1992, Chemotherapeutic efficacy of a newly synthesized benzoxazinorifamycin, KRM-1648, against Mycobacterium avium complex infection induced in mice. Antimicrobial Agents and Chemotherapy, 36, 387-393.
    • (1992) Antimicrobial Agents and Chemotherapy , vol.36 , pp. 387-393
    • Tomioka, H.1    Saito, H.2    Sato, K.3    Yamane, T.4    Yamashita, K.5    Hosoe, K.6    Fujh, K.7    Hidaka, T.8
  • 29
    • 0030999969 scopus 로고    scopus 로고
    • Metabolism rifabutin and its 25-desacetyl metabolite, LM565, by human liver microsomes and recombinant human cytochrome P-450 3A4: Relevance to clinical interaction with fluconazole
    • TRAPNELL, C. B., JAMIS-DOW, C., KLECKER, R. W. and COLLINS, J. M., 1997, Metabolism rifabutin and its 25-desacetyl metabolite, LM565, by human liver microsomes and recombinant human cytochrome P-450 3A4: relevance to clinical interaction with fluconazole. Antimicrobial Agents and Chemotherapy, 41, 924-926.
    • (1997) Antimicrobial Agents and Chemotherapy , vol.41 , pp. 924-926
    • Trapnell, C.B.1    Jamis-Dow, C.2    Klecker, R.W.3    Collins, J.M.4
  • 32
    • 0021996062 scopus 로고
    • Clinical significance of esterases in man
    • WILLIAMS, F. M., 1985, Clinical significance of esterases in man. Clinical Pharmacokinetics, 10, 392-403.
    • (1985) Clinical Pharmacokinetics , vol.10 , pp. 392-403
    • Williams, F.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.