-
1
-
-
0343343009
-
Warm hearts in a cold land
-
4 March
-
Kiernan V. Warm hearts in a cold land. New Scientist 4 March 1995:10.
-
(1995)
New Scientist
, pp. 10
-
-
Kiernan, V.1
-
2
-
-
0028028224
-
Chopin's illnesses
-
Kuzemko JA. Chopin's illnesses. J R Soc Med 1994;87:769-72.
-
(1994)
J R Soc Med
, vol.87
, pp. 769-772
-
-
Kuzemko, J.A.1
-
3
-
-
0031974454
-
The long suffering of Frederic Chopin
-
Kubba AK, Young M. The long suffering of Frederic Chopin. Chest 1997;113:210-6.
-
(1997)
Chest
, vol.113
, pp. 210-216
-
-
Kubba, A.K.1
Young, M.2
-
5
-
-
0019321009
-
Kinetics of association of serine proteinases with native and oxidized α-1-proteinase inhibitor and α-1-antichymotrypsin
-
Beatty K, Bieth J, Travis J. Kinetics of association of serine proteinases with native and oxidized α-1-proteinase inhibitor and α-1-antichymotrypsin. J Biol Chem 1980;255:3931-4.
-
(1980)
J Biol Chem
, vol.255
, pp. 3931-3934
-
-
Beatty, K.1
Bieth, J.2
Travis, J.3
-
7
-
-
0013828812
-
1-antitrypsin deficiency
-
1-antitrypsin deficiency. Acta Med Scand 1965;432(Suppl):1-85.
-
(1965)
Acta Med Scand
, vol.432
, Issue.SUPPL.
, pp. 1-85
-
-
Eriksson, S.1
-
8
-
-
0032085755
-
Alpha1-antitrypsin deficiency, cirrhosis and emphysema
-
Mahadeva R, Lomas DA. Alpha1-antitrypsin deficiency, cirrhosis and emphysema. Thorax 1998;53: 501-5.
-
(1998)
Thorax
, vol.53
, pp. 501-505
-
-
Mahadeva, R.1
Lomas, D.A.2
-
11
-
-
0029925466
-
C-antineutrophil cytoplasmic antibody positivity in vasculitis patients is associated with the Z allele of alpha-1-antitrypsin, and P-antineutrophil cytoplasmic antibody positivity with the S allele
-
Griffith ME, Lovegrove JU, Gaskin G, Whitehouse DB, Pusey CD. C-antineutrophil cytoplasmic antibody positivity in vasculitis patients is associated with the Z allele of alpha-1-antitrypsin, and P-antineutrophil cytoplasmic antibody positivity with the S allele. Nephrol Dial Transplant 1996;11:438-43.
-
(1996)
Nephrol Dial Transplant
, vol.11
, pp. 438-443
-
-
Griffith, M.E.1
Lovegrove, J.U.2
Gaskin, G.3
Whitehouse, D.B.4
Pusey, C.D.5
-
12
-
-
0023898432
-
Molecular basis of alpha-1-antitrypsin deficiency
-
Brantly M, Nukiwa T, Crystal RG. Molecular basis of alpha-1-antitrypsin deficiency. Am J Med 1988;84(Suppl 6A):13-31.
-
(1988)
Am J Med
, vol.84
, Issue.SUPPL. 6A
, pp. 13-31
-
-
Brantly, M.1
Nukiwa, T.2
Crystal, R.G.3
-
14
-
-
0017163949
-
1-antitrypsin PiZ
-
1-antitrypsin PiZ. FEBS Lett 1976;65:195-7.
-
(1976)
FEBS Lett
, vol.65
, pp. 195-197
-
-
Jeppsson, J.-O.1
-
15
-
-
0017195778
-
Molecular abnormality of human alpha 1-antitrypsin variant (Pi-ZZ) associated with plasma activity deficiency
-
Yoshida A, Lieberman J, Gaidulis L, Ewing C. Molecular abnormality of human alpha 1-antitrypsin variant (Pi-ZZ) associated with plasma activity deficiency. Proc Natl Acad Sci USA 1976;73:1324-8.
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 1324-1328
-
-
Yoshida, A.1
Lieberman, J.2
Gaidulis, L.3
Ewing, C.4
-
16
-
-
0017099344
-
Liver disease in alpha 1-antitrypsin deficiency detected by screening of 200,000 infants
-
Sveger T. Liver disease in alpha 1-antitrypsin deficiency detected by screening of 200,000 infants. N Engl J Med 1976;294:1316-21.
-
(1976)
N Engl J Med
, vol.294
, pp. 1316-1321
-
-
Sveger, T.1
-
17
-
-
0024238708
-
1-antitrypsin deficient children
-
1-antitrypsin deficient children. Acta Paediatr Scand 1988;77:847-51.
-
(1988)
Acta Paediatr Scand
, vol.77
, pp. 847-851
-
-
Sveger, T.1
-
18
-
-
0022637178
-
Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency
-
Eriksson S, Carlson J, Velez R. Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency. N Engl J Med 1986;314: 736-9.
-
(1986)
N Engl J Med
, vol.314
, pp. 736-739
-
-
Eriksson, S.1
Carlson, J.2
Velez, R.3
-
19
-
-
0028206262
-
The serpin superfamily of proteinase inhibitors: Structure, function, and regulation
-
Potempa J, Korzus E, Travis J. The serpin superfamily of proteinase inhibitors: structure, function, and regulation. J Biol Chem 1994; 269:15957-60.
-
(1994)
J Biol Chem
, vol.269
, pp. 15957-15960
-
-
Potempa, J.1
Korzus, E.2
Travis, J.3
-
20
-
-
0024423930
-
1-antitrypsin for structure and function of serpins
-
1-antitrypsin for structure and function of serpins. Biochemistry 1989;28:8951-66.
-
(1989)
Biochemistry
, vol.28
, pp. 8951-8966
-
-
Huber, R.1
Carrell, R.W.2
-
22
-
-
0018276853
-
Structural evidence for methionine at the reactive site of human α-1-proteinase inhibitor
-
Johnson D, Travis J. Structural evidence for methionine at the reactive site of human α-1-proteinase inhibitor. J Biol Chem 1978; 253:7142-4.
-
(1978)
J Biol Chem
, vol.253
, pp. 7142-7144
-
-
Johnson, D.1
Travis, J.2
-
23
-
-
0031036673
-
Major proteinase movement upon stable serpin-proteinase complex formation
-
Stratikos E, Gettins PGW. Major proteinase movement upon stable serpin-proteinase complex formation. Proc Natl Acad Sci USA 1997;4:453-8.
-
(1997)
Proc Natl Acad Sci USA
, vol.4
, pp. 453-458
-
-
Stratikos, E.1
Gettins, P.G.W.2
-
24
-
-
0031134386
-
Structural insights into serpin-protease complexes reveal the inhibitory mechanism of serpins
-
Wilczynska M, Fa M, Karolin J, Ohlsson P-I, et al. Structural insights into serpin-protease complexes reveal the inhibitory mechanism of serpins. Nat Struc Biol 1997;4:354-7.
-
(1997)
Nat Struc Biol
, vol.4
, pp. 354-357
-
-
Wilczynska, M.1
Fa, M.2
Karolin, J.3
Ohlsson, P.-I.4
-
25
-
-
0025828198
-
2-antiplasmin, angiotensinogen, and ovalbumin
-
2-antiplasmin, angiotensinogen, and ovalbumin. Biochemistry 1991;30:1723-30.
-
(1991)
Biochemistry
, vol.30
, pp. 1723-1730
-
-
Mast, A.E.1
Enghild, J.J.2
Pizzo, S.V.3
Salvesen, G.4
-
30
-
-
0032538299
-
Implications for function and therapy of a 2.9 Å structure of binary-complexed antithrombin
-
Skinner R, Chang W-SW, Jin L, Pei X, et al. Implications for function and therapy of a 2.9 Å structure of binary-complexed antithrombin. J Mol Biol 1998;283:9-14.
-
(1998)
J Mol Biol
, vol.283
, pp. 9-14
-
-
Skinner, R.1
Chang, W.-S.W.2
Jin, L.3
Pei, X.4
-
32
-
-
0021151426
-
Occurrence of alpha-1-antitrypsin deficiency in 155 patients with alcoholic liver disease
-
Roberts EA, Cox DW, Medline A, Wanless IR. Occurrence of alpha-1-antitrypsin deficiency in 155 patients with alcoholic liver disease. Am J Clin Pathol 1984;82:424-7.
-
(1984)
Am J Clin Pathol
, vol.82
, pp. 424-427
-
-
Roberts, E.A.1
Cox, D.W.2
Medline, A.3
Wanless, I.R.4
-
34
-
-
0029012309
-
52Phe deleted) forms loop-sheet polymers in vivo: Evidence for the C sheet mechanism of polymerisation
-
52Phe deleted) forms loop-sheet polymers in vivo: evidence for the C sheet mechanism of polymerisation. J Biol Chem 1995;270:16864-70.
-
(1995)
J Biol Chem
, vol.270
, pp. 16864-16870
-
-
Lomas, D.A.1
Elliott, P.R.2
Sidhar, S.K.3
Foreman, R.C.4
-
37
-
-
15844416550
-
1-antitrypsin Z and S is distinct from that for an unassembled membrane protein
-
1-antitrypsin Z and S is distinct from that for an unassembled membrane protein. J Biol Chem 1996;271:13215-20.
-
(1996)
J Biol Chem
, vol.271
, pp. 13215-13220
-
-
Teckman, J.H.1
Perlmutter, D.H.2
-
38
-
-
0017888482
-
1-antitrypsin deficiency in early childhood
-
1-antitrypsin deficiency in early childhood. Pediatrics 1978;62:22-5.
-
(1978)
Pediatrics
, vol.62
, pp. 22-25
-
-
Sveger, T.1
-
41
-
-
0032586927
-
Decline in FEV1 related to smoking status in individuals with severe alpha1-antitrypsin deficiency
-
Piitulainen E, Eriksson S. Decline in FEV1 related to smoking status in individuals with severe alpha1-antitrypsin deficiency. Eur Respir J 1999;13:247-51.
-
(1999)
Eur Respir J
, vol.13
, pp. 247-251
-
-
Piitulainen, E.1
Eriksson, S.2
-
42
-
-
0018128288
-
Natural history and life expectancy in severe alpha1-antitrypsin deficiency, PiZ
-
Larsson C. Natural history and life expectancy in severe alpha1-antitrypsin deficiency, PiZ. Acta Med Scand 1978;204:345-51.
-
(1978)
Acta Med Scand
, vol.204
, pp. 345-351
-
-
Larsson, C.1
-
44
-
-
0027923966
-
436→Thr) results in nonsubstrate-like behavior and in polymerization of the molecule
-
436→Thr) results in nonsubstrate-like behavior and in polymerization of the molecule. J Biol Chem 1993;268:18088-94.
-
(1993)
J Biol Chem
, vol.268
, pp. 18088-18094
-
-
Aulak, K.S.1
Eldering, E.2
Hack, C.E.3
Lubbers, Y.P.T.4
-
45
-
-
0028855465
-
COOH-terminal substitutions in the serpin C1 inhibitor that cause loop over-insertion and subsequent multimerization
-
Eldering E, Verpy E, Roem D, Meo T, Tosi M. COOH-terminal substitutions in the serpin C1 inhibitor that cause loop over-insertion and subsequent multimerization. J Biol Chem 1995;270: 2579-87.
-
(1995)
J Biol Chem
, vol.270
, pp. 2579-2587
-
-
Eldering, E.1
Verpy, E.2
Roem, D.3
Meo, T.4
Tosi, M.5
-
46
-
-
0027999955
-
Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 AsnvAsp)
-
Bruce D, Perry DJ, Borg J-Y, Carrell RW, Wardell MR. Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 AsnvAsp). J Clin Invest 1994;94: 2265-74.
-
(1994)
J Clin Invest
, vol.94
, pp. 2265-2274
-
-
Bruce, D.1
Perry, D.J.2
Borg, J.-Y.3
Carrell, R.W.4
Wardell, M.R.5
-
47
-
-
0028915906
-
382 to Thr) causing severe thromboembolic tendency undergoes the S-to-R transition and is associated with a plasma-inactive high-molecular-weight complex of aggregated antithrombin
-
382 to Thr) causing severe thromboembolic tendency undergoes the S-to-R transition and is associated with a plasma-inactive high-molecular-weight complex of aggregated antithrombin. Br J Haematol 1995;89:589-601.
-
(1995)
Br J Haematol
, vol.89
, pp. 589-601
-
-
Lindo, V.S.1
Kakkar, V.V.2
Learmonth, M.3
Melissari, E.4
-
48
-
-
0027328108
-
1-antichymotrypsin allele associated with familial obstructive lung disease
-
1-antichymotrypsin allele associated with familial obstructive lung disease. Genomics 1993;17:740-3.
-
(1993)
Genomics
, vol.17
, pp. 740-743
-
-
Poller, W.1
Faber, J.-P.2
Weidinger, S.3
Tief, K.4
-
49
-
-
0027169598
-
1-antichymotrypsin deficiency in a heterozygote with liver and lung disease
-
1-antichymotrypsin deficiency in a heterozygote with liver and lung disease. J Hepatol 1993;18:313-21.
-
(1993)
J Hepatol
, vol.18
, pp. 313-321
-
-
Faber, J.-P.1
Poller, W.2
Olek, K.3
Baumann, U.4
-
50
-
-
0034602778
-
1-antichymotrypsin indicates two stage insertion of the reactive loop; implications for inhibitory function and conformational disease
-
1-antichymotrypsin indicates two stage insertion of the reactive loop; implications for inhibitory function and conformational disease. Proc Natl Acad Sci USA 2000; 97:67-72.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 67-72
-
-
Gooptu, B.1
Hazes, B.2
Chang, W.-S.W.3
Dafforn, T.R.4
-
51
-
-
0033598346
-
Familial dementia caused by polymerisation of mutant neuroserpin
-
Davis RL, Shrimpton AE, Holohan PD, Bradshaw C, et al. Familial dementia caused by polymerisation of mutant neuroserpin. Nature 1999;401:376-9.
-
(1999)
Nature
, vol.401
, pp. 376-379
-
-
Davis, R.L.1
Shrimpton, A.E.2
Holohan, P.D.3
Bradshaw, C.4
-
52
-
-
0023148995
-
Replacement therapy for alpha1-antitrypsin deficiency associated with emphysema
-
Wewers MD, Casolaro MA, Sellers SE, Swayze SC, et al. Replacement therapy for alpha1-antitrypsin deficiency associated with emphysema. N Engl J Med 1987;316:1055-62.
-
(1987)
N Engl J Med
, vol.316
, pp. 1055-1062
-
-
Wewers, M.D.1
Casolaro, M.A.2
Sellers, S.E.3
Swayze, S.C.4
-
53
-
-
0032110436
-
1-antitrypsin
-
1-antitrypsin. Am J Respir Crit Care Med 1998;158:49-59.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 49-59
-
-
-
55
-
-
16944366965
-
Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats
-
Massaro GD, Massaro D. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat Med 1997;3:675-7.
-
(1997)
Nat Med
, vol.3
, pp. 675-677
-
-
Massaro, G.D.1
Massaro, D.2
-
56
-
-
0030841343
-
Conformational diseases
-
Carrell RW, Lomas DA. Conformational diseases. Lancet 1997;350: 134-8.
-
(1997)
Lancet
, vol.350
, pp. 134-138
-
-
Carrell, R.W.1
Lomas, D.A.2
-
57
-
-
0030470459
-
Glutamine repeats and inherited neurodegenerative diseases: Molecular aspects
-
Perutz MF. Glutamine repeats and inherited neurodegenerative diseases: molecular aspects. Curr Opin Struc Biol 1996;6:848-58.
-
(1996)
Curr Opin Struc Biol
, vol.6
, pp. 848-858
-
-
Perutz, M.F.1
-
58
-
-
0028982272
-
Amyloid β-protein aggregation nullifies its pathogenic properties in cultured cerebrovascular smooth muscle cells
-
Davis-Salinas J, Van Nostranel WE. Amyloid β-protein aggregation nullifies its pathogenic properties in cultured cerebrovascular smooth muscle cells. J Biol Chem 1995;270:20887-90.
-
(1995)
J Biol Chem
, vol.270
, pp. 20887-20890
-
-
Davis-Salinas, J.1
Van Nostranel, W.E.2
-
59
-
-
0013511416
-
Prion diseases of humans and animals
-
Prusiner SB. Prion diseases of humans and animals. J R Coll Physicians Lond 1994;28:1-30.
-
(1994)
J R Coll Physicians Lond
, vol.28
, pp. 1-30
-
-
Prusiner, S.B.1
-
60
-
-
0031873102
-
β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy
-
Soto C, Sigurdsson EM, Morelli L, Kumar RA, et al. β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nat Med 1998;4:822-6.
-
(1998)
Nat Med
, vol.4
, pp. 822-826
-
-
Soto, C.1
Sigurdsson, E.M.2
Morelli, L.3
Kumar, R.A.4
|