KPL1, which encodes a novel PH domain-containing protein, is induced during ciliated cell differentiation of rat tracheal epithelial cells

Experimental Lung Research

Volumn 26, Issue 4, 2000, Pages 257-271

  Andrews, Kaya L ^a,b   Potdar, Pravin D ^a,c   Nettesheim, Paul ^a   Ostrowski, Lawrence E ^a,d  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c TATA MEMORIAL HOSPITAL   (India)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Ciliogenesis; Differentiation; Pleckstrin homology domain; Tracheal epithelial cells

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PLECKSTRIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CILIATED EPITHELIUM; CONTROLLED STUDY; GENE AMPLIFICATION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; RAT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRACHEA MUCOSA;

EID: 0033916852     PISSN: 01902148     EISSN: None     Source Type: Journal    
DOI: 10.1080/019021400404537     Document Type: Article

References (25)

1. 1. Kaartinen L, Nettesheim P, Adler KB, Randell SH: Rat tracheal epithelial cell differentiation in vitro. In Vitro Cell Dev Biol. 1993;29A:481-492.
2. 2. Gray TE, Guzman K, Davis CW, Abdullah LH, Nettesheim P: Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells. 1996 Am J Respir Cell Mol Biol. 1996;14:104-112.
3. 3. Jetten AM, Brody AR, Deas MA, Hook GER, Rearick JI, Thacher SM: Retinoic acid and substratum regulate the differentiation of rabbit tracheal epithelial cells into squamous and secretory phenotype. Lab Invest. 1987;56:654-664.
4. 4. Clark AB, Randell SH, Nettesheim P, Gray TE, Bagnell B, Ostrowski LE: Regulation of ciliated cell differentiation in cultures of rat tracheal epithelial cells. Am J Respir Cell Mol Biol. 1995;12:329-338.
5. 5. Ostrowski LE, Nettesheim P: Regulation of ciliated cell differentiation of rat tracheal epithelial cells by submersion. Exp Lung Res. 1995;21:957-970.
6. 6. Ostrowski LE, Randell SH, Clark AB, Gray TE, Nettesheim P: Ciliogenesis of rat tracheal epithelial cells in vitro. Methods Cell Biol. 1995;47:57-63.
7. 7. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Anal Biochem. 1987;162:156-159.
8. 8. Guzman K, Bader T, Nettesheim P: Regulation of MUC5 and MUC1 gene expression: correlation with airway mucous differentiation. Am J Physiol. 1996;270:L846-L853.
9. 9. Andrews KL, Nettesheim P, Asai DJ, Ostrowski LE: Identification of seven rat axonemal dynein heavy chain genes: expression during ciliated cell differentiation. Mol Biol Cell. 1996;7:71-79.
10. 10. Nudel U, Zakut R, Shani M, Neuman S, Levy Z, Yaffe D: The nucleotide sequence of the rat cytoplasmic β-actin gene. Nucleic Acids Res 1983;11:1759-1771.
11. 11. Ostrowski LE, Andrews K, Potdar P, Matsuura H, Jetten A, Nettesheim P: Cloning and characterization of KPL2, a novel gene induced during ciliogenesis of tracheal epithelial cells. Am J Respir Cell Mol Biol. 1999;20:675-683.
12. 12. Guzman K, Randell SH, Nettesheim P: Epidermal growth factor regulates expression of the mucous phenotype of rat tracheal epithelial cells. Biochem Biophys Res Commun. 1995;217:412-418.
13. 13. Lemmon MA, Ferguson KM, Schlessinger J: PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell. 1996;85:621-624.
14. 14. Shaw G: The pleckstrin homology domain: an intriguing multifunctional protein module. Bioessays. 1995;18:35-46.
15. 15. Derry JMJ, Ochs HD, Francke U: Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell. 1994;78:635-644.
16. 16. Kwan SP, Hagemann TL, Radtke BE, Blaese RM, Rosen FS: Identification of mutations in the Wiskott-Aldrich syndrome gene and characterization of a polymorphic dinucleotide repeat at DXS6940, adjacent to the disease gene. Proc Natl Acad Sci USA. 1995;92:4706-4710.
17. 17. de Weers M, Mensink RGJ, Kraakman MEM, Schuurman RKB, Hendriks RW: Mutation analysis of the Bruton's tryosine kinase gene in X-linked agammaglobulinemia: identification of a mutation which affects the same codon as is altered in immunodeficient xid mice. Hum Mol Genet. 1994;3:161-166.
18. 18. Salim K, Bottomley MJ, Querfurth E, Zvelebil MJ, Gout I, Scaife R, Margolis RL, Gigg R, Smith CIE, Driscill PC, Waterfield MD, Panayotou G: Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tryosine kinase. EMBO J. 1996;15:6241-6250.
19. 19. Kubiseski TJ, Chook YM, Parris WE, Rozakis-Adcock M, Pawson T: High affinity binding of the pleckstrin homology domain of mSos1 to phosphatidylinsositol (4,5)-biphosphate. J Biol Chem. 1997;272:1799-1804.
20. 20. Klarlund JK, Guilherme A, Holik JJ, Virbasius JV, Chawla A, Czech MP: Signaling by phosphoinositide-3,4,5-triphosphate through proteins containing pleckstrin and Sec7 homology domains. Science. 1997;275:1927-1930.
21. 21. Abrams CS, Zhao W, Brass LF: A site of interaction between pleckstrin's PH domains and G beta gamma. Biochim Biophys Acta 1996;1314:233-238.
22. 22. Yao L, Kawakami Y, Kawakami T: The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C. Proc Natl Acad Sci USA. 1994;91:9175-9179.
23. 23. Yao L, Suzuki H, Ozawa K, Deng J, Lehel C, Fukamachi H, Anderson WB, Kawakami Y, Kawakami T: Interactions between protein kinase C and pleckstrin homology domains. J Biol Chem. 1997;272:13033-13039.
24. 24. Abrams CS, Zhao W, Belmonte E, Brass LF: Protein kinase C regulates pleckstrin by phosphorylation of sites adjacent to the N-terminal pleckstrin homology domain. J Biol Chem. 1995;270:23317-23321.
25. 25. Krappa R, Nguyen A, Burrola P, Deretic D, Lemke G: Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes. Proc Natl Acad Sei USA. 1999;96:4633-4638.