Elucidation of structure-activity relationships of 2-amino-3- benzoylthiophenes: Study of their allosteric enhancing vs. antagonistic activity on adenosine A1 receptors

Drug Development Research

Volumn 49, Issue 4, 2000, Pages 227-237

  Kourounakis, Angeliki P ^a   Van Der Klein, Pieter A M ^a   Ijzerman, Ad P ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Adenosine receptor; Allosteric modulation; G protein coupled receptors; PD81,723

Indexed keywords

(2 AMINO 5 CYCLOHEXYL 3 THIENYL)(3 CHLOROPHENYL)METHANONE; 2 AMINO 4,5 DIMETHYL 3 (3 TRIFLUOROMETHYLBENZOYL)THIOPHENE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; THEOPHYLLINE; THEOPHYLLINE DERIVATIVE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; STRUCTURE ACTIVITY RELATION;

EID: 0033916799     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2299(200004)49:4<227::AID-DDR1>3.0.CO;2-1     Document Type: Article

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