Multifocal motor neuropathy: Serum IgM binding to a GM1 ganglioside- containing lipid mixture but not to GM1 alone

Neurology

Volumn 48, Issue 4, 1997, Pages 1104-1106

  Pestronk, Alan ^a,b   Choksi, Rati ^a   Blume, Gregory ^a   Lopate, Glenn ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Box 8111 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOSIDE GM1;

ADULT; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; BINDING AFFINITY; CLINICAL ARTICLE; DRUG BLOOD LEVEL; ELECTRODIAGNOSIS; FEMALE; HUMAN; LIGAND BINDING; MALE; MOTOR NEUROPATHY; MUSCLE WEAKNESS; PERIPHERAL NERVE; PRIORITY JOURNAL;

EID: 0030946473     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.48.4.1104     Document Type: Article

References (10)

1. Pestronk A, Cornblath DR, Ilyas AA, et al. A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside. Ann Neurol 1988;24:73-78.
2. Kornberg AJ, Pestronk A. Chronic motor neuropathies: diagnosis, therapy, and pathogenesis. Ann Neurol 1995;37:S43-S50.
3. Parry GJ. Motor neuropathy with multifocal conduction block. In: Dyck PJ, Thomas PK, eds. Peripheral neuropathy. 3rd ed. Philadelphia: WB Saunders, 1993:1518-1524.
4. Kornberg AJ, Pestronk A. The clinical and diagnostic role of anti-GM1 antibody testing. Muscle Nerve 1994;17:100-104.
5. Pestronk A, Li F, Bieser K, et al. Anti-MAG antibodies: major effects of antigen purity and antibody cross-reactivity on ELISA results and clinical correlation. Neurology 1994;44: 1131-1137.
6. Pestronk A, Chaudhry V, Feldman EL, et al. Lower motor neuron syndromes defined by patterns of weakness, nerve conduction abnormalities, and high titers of antiglycolipid antibodies. Ann Neurol 1990;27:316-326.
7. Li F, Pestronk A. Autoantibodies to GM1 ganglioside: different reactivity to GM1-liposomes in amyotrophic lateral sclerosis and lower motor neuron disorders. J Neurol Sci 1991;104: 209-214.
8. Kinsella LJ, Lange DJ, Trojaborg W, Sadiq SA, Younger DS, Latov N. Clinical and electrophysiologic correlates of elevated anti-GM1 antibody titers. Neurology 1994;44:1278-1282.
9. Adams D, Kuntzer T, Burger D, et al. Predictive value of anti-GM1 ganglioside antibodies in neuromuscular diseases: a study of 180 sera. J Neuroimmunol 1991;32:223-230.
10. Monestier M, Kotzin BL. Antibodies to histones in systemic lupus erythematosus and drug-induced lupus syndromes. Rheum Dis Clin North Am 1992;18:415-436.