Role of phospholipid transfer protein in high-density lipoprotein metabolism: Insights from studies in transgenic mice

International Journal of Tissue Reactions

Volumn 22, Issue 2-3, 2000, Pages 79-84

  Van Tol, A ^a   Jauhiainen, M ^a   De Crom, R ^a   Ehnholm, C ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN; PHOSPHOLIPID; PHOSPHOLIPID TRANSFER PROTEIN;

LIPOPROTEIN METABOLISM; NONHUMAN; REVIEW;

ADENOVIRIDAE; ANIMALS; APOLIPOPROTEIN A-I; CARRIER PROTEINS; CHOLESTEROL; GENE EXPRESSION; GENE TARGETING; GENETIC VECTORS; HUMANS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; MACROPHAGES, PERITONEAL; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; PHOSPHOLIPID TRANSFER PROTEINS; PHOSPHOLIPIDS;

EID: 0033916336     PISSN: 02500868     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (23)

1. Early incorporation of cell-derived cholesterol into pre-β-migrating high-density lipoprotein
2. The plasma lecithin: Cholesterol acyltransferase reaction
3. Role of the phospholipid transfer protein in plasma lipid transport
4. Transfers and exchange of esterified cholesterol between plasma lipoproteins
5. Preparation, characterization and measurement of hepatic lipase
6. In vitro remodelling of plasma lipoproteins in whole plasma by lipoprotein lipase in primary and secondary hypertriglyceridaemia
7. Remodelling of high-densitylipoproteins by plasma factors
8. Human plasma phospholipid transfer protein causes high-density lipoprotein conversion
9. Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels
10. The mechanism of human plasma phospholipid transfer protein-induced enlargement of high-density lipoprotein particles: Evidence of particle fusion
11. Transformation of high density lipoprotein particles by hepatic lipase and phospholipid transfer protein
12. Phospholipid transfer protein mediated conversion of high-densitylipoproteins generates pre-β-HDL
13. ApoA-II/apoA-I molar ratio in the HDL particle influences phospholipid transfer protein mediated HDL interconversion
14. Triglyceride enrichment of high density lipoproteins enhances their remodelling by phospholipid transfer protein
15. Transgenic mice expressing human phospholipid transfer protein have increased HDL/non-HDL cholesterol ratio
16. Increased pre-β-high density lipoprotein, apoprotein A-I, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein A-I transgenes
17. Human plasma phospholipid transfer protein increases the anti-atherogenic potential of high-density lipoproteins in transgenic mice
18. Regulation of the concentration of prebeta high density lipoprotein in normal plasma by cell membranes and lecithin-cholesterol acyltransferase activity
19. Synergism of plasma phospholipid transfer protein and apolipoprotein A-I in increasing high density lipoprotein size in transgenic mice: Consequences for cholesterol accumulation in macrophages
20. Plasma phospholipid transfer protein-adenovirus-mediated overexpression in mice leads to decreased plasma high density lipoprotein (HDL) and enhanced hepatic uptake of phospholipid and cholesteryl esters from HDL
21. Adenovirus mediated overexpression of human phospholipid transfer protein alters plasma HDL levels in mice
22. Plasma phospholipid transfer protein enhances transfer and exchange of phospholipids between very low density lipoproteins and high density lipoproteins during lipolysis
23. Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins