Heparin use in pediatric bypass - Empirical regimen (ACT) vs. heparin concentration: A multicenter trial

Journal of Extra-Corporeal Technology

Volumn 32, Issue 2, 2000, Pages 84-88

  Olshove, Vincent ^a   Tallman, Richard ^b  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Activated clotting time; Heparin; Pediatric cardiopulmonary bypass

Indexed keywords

HEPARIN;

ANTICOAGULANT THERAPY; BLOOD CLOTTING TIME; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CONFERENCE PAPER; DRUG USE; EXTRACORPOREAL CIRCULATION; HUMAN;

EID: 0033916244     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (12)

1. Hattersley P. Activated coagulation time of whole blood. JAMA. 1966;195:150-4.
2. Bull M, Huse W, Bull B. Evaluation of tests used to monitor heparin therapy during extracorporeal circulation. Anesthesiology, 1975;43:346-53.
3. Bull B, Huse W, Korpman R. Heparin therapy during extracorporeal circulation: II. The use of a dose response curve to individualize heparin and protamine dosage. J Thorac Cardiovasc Surg. 1975;69:685-9.
4. Cohen E, Camerlengo L, Dealing J. Activated clotting times and cardiopulmonary bypass I: The effect of hemodilution and hypothermia upon activated clotting time. J Extra-Corp Tech. 1980;12:139-41.
5. Culliford A, Gitell A, Starr N, et al. Lack of correlation between activated clotting time and plasma heparin during cardiopulmonary bypass. Ann Surg. 1981;193:105-11.
6. Gruenwald C, McDonough J, Noel D, Stokoe J, et al. Hemotec activated clotting time values are significantly lower than Hemochron values in children undergoing cardiopulmonary bypass. Proc Am Acad Cardiovasc Perf. 1992;13:91-4.
7. Cohen J, Bethea H, Rush W. Heparin kinetics during pediatric open-heart operations. Perfusion. 1986;1:271-5.
8. Horkay F, Martin P, Rajah M, et al. Response to heparinization in adults and children undergoing cardiac operations. Ann Thorac Surg. 1992:53:822-6.
9. Gravlee G, Haddon W, Rothberger H, et al. Heparin dosing and monitoring for cardiopulmonary bypass. A comparison of techniques with measurement of subclinical plasma coagulation. J Thorac Cardiovasc Surg. 1990;99: 518-27.
10. Gravlee G, Rogers A, Dudas L, et al. Heparin management protocol for cardiopulmonary bypass influences postoperative heparin rebound but not bleeding. Anesthesiology. 1992;76:393-401.
11. Turner-Gromes S, Nitschmann E, Norman G, et al. Effect of heparin loading during congenital heart operation on thrombin generation and blood loss. Ann Thorac Surg. 1997;63:482-88.
12. Dauchot P, Berzina-Moettus L, Rabinovitch A, et al. Activated coagulation and activate partial thromboplastin times in assessment and reversal of heparin-induced anticoagulation for cardiopulmonary bypass. Anesth Analg. 1983;62:710-19.