Nutrition as primary therapy in pediatric Crohn's disease: Fact or fantasy?

Journal of Pediatrics

Volumn 136, Issue 3, 2000, Pages 285-291

  Ruemmele, Frank M ^b   Roy, Claude C ^b   Levy, Emile ^b   Seidman, Ernest G ^a  

^a UNIVERSITY OF MONTREAL   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CROHN DISEASE; DIET THERAPY; HUMAN; IMMUNOMODULATION; INTESTINE FUNCTION; MALNUTRITION; NUTRITIONAL SUPPORT; PRIORITY JOURNAL; REVIEW; TREATMENT INDICATION;

EID: 0033913792     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1067/mpd.2000.104537     Document Type: Article

References (50)

1. 1. Kirsner JB. The historical basis of the idiopathic inflammatory bowel disease. Inflamm Bowel Dis 1995;1:2-26.
2. 2. Barton JR, Gillon S, Ferguson A. Incidence of Crohn's disease in Scottish children between 1968 and 1983. Gut 1989;30:618-22.
3. 3. Seidman EG. Inflammatory bowel diseases. In: Roy C, Silverman A, Alagille D, editors. Pediatric gastrointestinal disease. 4th ed. St Louis: Mosby; 1996. p. 585-605.
4. 4. Leichtner AM, Jackson WD, Grand RJ. Crohn's disease. In: Walker WA, Durie PR, Hamilton JR, Walker-Smith JA, Watkins JB, editors. Pediatric gastrointestinal disease. 2nd ed. St Louis: Mosby; 1996. p. 692-711.
5. 5. Seidman EG. Nutritional management of inflammatoty bowel disease. Gastroenterol Clin North Am 1989;18: 129-55.
6. 6. O'Morain C, Segal AW, Levi AJ. Elemental diets in treatment of acute Crohn's disease. BMJ 1980;281:1173-5.
7. 7. Seidman E, Le Leiko N, Ament M, Berman W, Caplan D, Evans J, et al. Nutritional issues in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1991;12:424-38.
8. 8. Seidman E, Justinich C, Roy CC. Use of elemental diet therapy in pediatric inflammatory bowel disease. In: Bounos G, editor. Uses of elemental diets in clinical situations. Boca Raton (FL: CRC Press; 1993. p. 243-63.
9. 9. Kelts DG, Grand RJ, Shen G, Watkins JB, Wenlen SH, Boehme C. Nutritional basis of growth failure in children and adolescents with Crohn's disease. Gastroenterology 1979;76:720-7.
10. 10. Grimble RF. Nutrition and cytokine action. Nutr Res Rev 1990;2:193-210.
11. 11. Seidman EG, Roy CC, Weber AM, Morin CL. Nutritional therapy of Crohn's disease in childhood. Dig Dis Sci 1988;32:82S88S.
12. 12. Seidman E, Bagnell P, Griffiths AM, Issenman R, Jones A. Canadian Collaborative Pediatric Crohn's disease Study: growth failure and nutritional deficiencies in pediatric patients with active Crohn's disease [abstract]. Gastroenterology 1991;100:A249.
13. 13. Markowitz J, Grancher K, Rosa J, Aiges H, Daum F. Growth failure in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1994;18: 165-73.
14. 14. Seidman E. Nutritional therapy for Crohn's disease: lessons from the Ste-Justine Hospital experience. Inflamm Bowel Dis 1997;3:49-53.
15. 15. Hyams JS, Carey DE. Corticosteroids and growth. J Pediatr 1988;113:249-55.
16. 16. Vointk AJ, Echave V, Feller JH, Brown RA, Gurd FN. Experience with elemental diet in the treatment of inflammatory bowel disease. Is this primary therapy? Arch Surg 1973;107:329-33.
17. 17. Lochs H, Steinhardt HJ, Klaus-Wentz B, Zeitz M, Vogelsang H, Sommer H, et al. Comparison of enteral nutrition and drug treatment in active Crohn's disease. Results of the European Cooperative Crohn's disease study IV. Gastroenterology 1991;101:881-8.
18. 18. Gonzalez-Huix F, de Leon R, Fernandez-Banares F, Esteve M, Cabre E, Acero D, et al. Polymeric enteral diets as primary treatment of active Crohn's disease: a prospective steroid controlled trial. Gut 1993;34:778-82.
19. 19. Malchow H, Ewe K, Brandes JW, Goebell H, Ehms H, Sommer H, et al. European Cooperative Crohn's Disease Study: results of drug treatment. Gastroenterology 1984;86:249-66.
20. 20. Lindor KD, Fleming R, Burnes JU, Nelson JK, Ilstrup DM. A randomized prospective trial comparing a defined formula diet, corticosteroids and a defined formula diet plus corticosteroids in active Crohn's disease. Mayo Clin Proc 1992;67:328-33.
21. 21. Gorard DA, Hunt JG, Payne-James JJ, Paler KR, Rees RGP, Clark ML, et al. Initial response and subsequent course of Crohn's disease treated with elemental diet or prednisolone. Gut 1993;34:1198-202.
22. 22. Sanderson IR, Udeen S, Davies PSW, Savage MO, Walker-Smith JA. Remission induced by an elemental diet in small bowel Crohn's disease. Arch Dis Child 1987;61:123-7.
23. 23. Seidman EG, Lohoues MJ, Turgeon J, Bouthillier L, Morin CL. Elemental diet versus prednisone as initial therapy in Crohn's disease: early and long-term results [abstract]. Gastroenterology 1991;100:A250.
24. 24. Seidman EG, Griffiths AM, Jones A, Issenman R. The Canadian Pediatric Crohn's Disease Study Group. Semi-elemental diet versus prednisone in the treatment of active Crohn's disease in children and adolescents [abstract]. Gastroenterology 1993;104:A778.
25. 25. Griffiths AM, Ohlsson A, Sherman PM, Sutherland LR. Meta-analysis of enteral nutrition as a primary treatment of active Crohn's disease. Gastroenterology 1995;108:1056-67.
26. 26. Fernandez-Banares F, Cabre E, Esteve-Copmas M, Gasull MA. How effective is enteral nutrition in inducing clinical remission in active Crohn's disease? A meta-analysis of the randomized clinical trials. JPEN J Parenter Enteral Nutr 1995;19:356-64.
27. 27. Messori A, Trallori G, S'Albasio G, Milla M, Vannozzi G, Pacini F. Defined-formula diets versus steroids in the treatment of active Crohn's disease. A meta-analysis. Scand J Gastroenterol 1996;31:267-72.
28. 28. Seidman EG, Jones A, Issenman R, Griffiths A. Relapse prevention/ growth enhancement in pediatric Crohn's disease: multicenter randomized controlled trial of intermittent enteral nutrition versus alternate day prednisone [abstract]. J Pediatr Gastroenterol Nutr 1996;23:A344.
29. 29. Belli D, Seidman EG, Bouthillier L, Weber AM, Roy CC, Pletincx M, et al. Chronic intermittent elemental diet improves growth failure in children with Crohn's disease. Gastroenterology 1988;94:603-10.
30. 30. Belluzi A, Brignola C, Campieri M, Pera A, Boschi S, Miglioli M. Effect of an enteric coated fish oil preparation on relapses in Crohn's disease. N Engl J Med 1996;334:1557-60.
31. 31. Herzog D, Deslandres C, Martin S, Rasquin A, Alvarez F, Bouthillier L, et al. Cyclical exclusive semi-elemental diet therapy normalizes growth and decreases relapse rate in pediatric Crohn's disease [abstract]. Gastroenterology 1997;112:A995.
32. 32. Seidman E. Gastrointestinal benefits of enteral feeds. In: Baker S, Baker R, Davis A, editors. Pediatric enteral nutrition. New York: Chapman & Hall; 1994. p. 46-66.
33. 33. Nelson LM. Elemental diet composition and the structure and function of rat small intestine: comparison of the effects of two diets on morphology and in vivo absorption of water. JPEN J Parenter Enteral Nutr 1981;5:204-6.
34. 34. Morin CL, Ling V, Bourassa D. Small intestinal and colonic changes induced by a chemically defined diet. Dig Dis Sci 1980;25:123-8.
35. 35. Winitz M, Birnbaum SM, Sugimura T. Quantitative nutritional and in vivo metabolic studies with water-soluble chemically defined diets. In: Edsall JT, Jesse P, editors. Amino acids, proteins and cancer biochemistry. San Diego: Academic Press; 1966. p. 9-29.
36. 36. Ruemmele FM, Ruemmele C, Levy E, Seidman E. Les mécanismes moléculaires de la regulation du renouvellement des cellules épitheliales intestinales par des nutriments. Gastroenterol Clin Biol 1999;23:47-55.
37. 37. Hollander D. Crohn's disease - a permeability disorder of the tight junctions. Gut 1988;26:1621-4.
38. 38. Sartor RB. Cytokines in intestinal inflammation: pathophysiological and clinical considerations. Gastroenterology 1994;106:533-9.
39. 39. Teahon K, Smethurst P, Pearson M, Levi AJ, Bjarnson I. The effect of elemental diet on permeability and inflammation in Crohn's disease. Gastroenterology 1991;101:84-9.
40. 40. Logan RFA, Gillion J, Ferrington C, Ferguson A. Reduction of gastrointestinal protein loss by elemental diet in Crohn's disease of the small bowel. Gut 1981;22:383-7.
41. 41. Sanderson IR, Boulton P, Menzies I, Walker-Smith JA. Improvement of abnormal lactulose/rhamnose permeability in active Crohn's disease of the small bowel by an elemental diet. Gut 1987;28:1073-6.
42. 42. Johnstone BJ, Klassing KC. Aspects nutritionnels des cytokines leucocytaires. Nutr Clin Metabol 1990;4:7-29.
43. 43. Fell JME, Hollis A, Paintin M, Arnaud-Battandier F, Mac-Donald TT, Walker-Smith JA. Normalization of mucosal cytokine mRNA in association with clinical improvement in children with Crohn's disease treated with polymeric diet [abstract]. J Pediatr Gastroenterol Nutr 1998;26:A34.
44. 44. Lohoues MJ, Russo P, Gurbindo C, Roy C, Levy E, Lepage G, et al. Essential fatty acid deficiency improves the course of experimental colitis in the rat: possible role of dietary immunomodulation [abstract]. Gastroenterology 1992;102:A655.
45. 45. Royall D, Jeejeeboy KN, Baker JP, Allard JP, Habal FM, Cunnane SC, et al. Comparison of amino acid versus peptide based enteral diets in active Crohn's disease: clinical and nutritional outcome. Gut 1994;35:783-7.
46. 46. Tanaka S, Miura S, Kimura H, Ohkubo N, Tsuzuki Y, Fukumura D, et al. Amelioration of chronic inflammation by ingestion of elemental diet in a rat model of granulomatous enteritis. Dig Dis Sci 1997;42:408-19.
47. 47. Lorenz-Meyer H, Bauer P, Nicolay C, Schulz B, Purrmann J, Fleig WE, et al. Omega-3 fatty acids and low carbohydrate diet for maintenance of remission in Crohn's disease. Scand J Gastroenterol 1996;31:778-85.
48. 48. Vilaseca J, Salas A, Guarner F, Rodriguez R, Martinez M, Malagelada JR. Dietary fish oil reduces progression of chronic inflammatory lesions in a rat model of granulomatous colitis. Gut 1990;13:539-44.
49. 49. Wilschanski M, Sherman P, Pencharz P, Davis L, Corey M, Griffiths A. Supplementary enteral nutrition maintains remission in pediatric Crohn's disease. Gut 1996;38:543-8.
50. 50. Bouthillier L, Herzog D, Parent RN, Seidman E. Use of flavored elemental formulas in the treatment of pediatric Crohn's disease [abstract]. JPEN J Parenter Enteral Nutr 1996;20:A13.