Activity of Amaryllidaceae alkaloids on the blood pressure of normotensive rats

Pharmacy and Pharmacology Communications

Volumn 6, Issue 7, 2000, Pages 309-312

  Schmeda Hirschmann, Guillermo ^a   Rodríguez, Jaime A ^a   Loyola, José I ^a   Astudillo, Luis ^a   Bastida, Jaume ^b   Viladomat, Francesc ^b   Codina, Carles ^c  

^a UNIVERSIDAD DE TALCA   (Chile)

^b UNIVERSITY OF BARCELONA   (Spain)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ALKALOID; ANTIHYPERTENSIVE AGENT; CRINANE; GALANTAMINE; HOMOLYCORINE; ISMINE; LYCORINE; MESEMBRENONE; NATURAL PRODUCT; TAZETTINE; UNCLASSIFIED DRUG;

ADOLESCENT; ANTIHYPERTENSIVE ACTIVITY; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR EFFECT; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; HYPERTENSION; MALE; NONHUMAN; PLANT; RAT;

EID: 0033910888     PISSN: 14608081     EISSN: None     Source Type: Journal    
DOI: 10.1211/146080800128736105     Document Type: Article

References (12)

1. Bastida, J., Viladomat, F., Codina, C. (1998) Narcissus Alkaloids. In: Atta-Ur-Rahman (ed.) Studies in Natural Product Chemistry. Vol 20, Elsevier, Amsterdam, pp. 323-405
2. Campbell, W. E., Nair, J. J., Gammon, D. W., Bastida, J., Codina, C., Viladomat, F., Smith, P. J., Albrecht, C. F. (1998) Cytotoxic and antimalarial alkaloids from Brunsvigia littoralis. Planta Med. 64: 91-93
3. Desai, H. K., Hart, B. P., Caldwell, R. W., Jianzhong-Huang, J. H., Pelletier, S. W. (1998) Certain norditerpenoid alkaloids and their cardiovascular action. J. Nat. Prod. 26: 743-748
4. Gabrielsen, B., Monath, T. P., Huggins, J. W., Kefauver, D. F., Pettit, G. R., Groszek, G., Hollingshead, M., Kirsi, J. J., Shannon, W. M., Schubert, E. M., Dare, J., Ugarkar, B., Ussery, M. A., Phelan, M. J. (1992) Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances. J. Nat. Prod. 55: 1569-1581
5. Harvey, A. L. (1995) The pharmacology of galanthamine and its analogues. Pharmacol. Ther. 68: 113-128
6. Likhitwitayawuid, K., Angerhofer, C. K., Chai, H., Pezzuto, J. M., Cordell, G. S., Ruangrungsi, A. (1993) Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile. J. Nat. Prod. 56: 1331-1338
7. Mikami, M., Kitahara, M., Kitano, M., Ariki, Y., Mimaki, Y., Sashida, Y., Yamazaki, M., Yui, S. (1999) Suppressive activity of lycoricidinol (narciclasine) against cytotoxicity of neutrophil-derived calprotectin, and its suppressive effect on rat adjuvant arthritis model. Biol. Pharm. Bull. 22: 674-678
8. Mok, S. L., Yoganathan, K., Lim, T. M., Kam, T. S. (1998) Cardiovascular effects of aspidofractinine-type alkaloids from Kopsia. J. Nat. Prod. 61: 328-332
9. Schmeda-Hirschmann, G., Loyola, J. I., Sierra, J., Retamal, R., Rodriguez, J. (1992) Hypotensive effect and enzyme inhibition activity of Mapuche medicinal plant extracts. Phytother. Res. 6: 184-188
10. Taesotikul, T., Panthong, A., Kanjanapothi, D., Verpoorte, R., Scheffer, J. J. (1998) Cardiovascular activity of the crude alkaloid fraction from Tabernaemontana pandacaqui in the rat. J. Ethnopharmacol. 59: 131-137
11. Viladomat, F., Codina, C., Bastida, J., Mathee, S., Campbell, W. E. (1995) Further alkaloids from Brungsvigia josephinae. Phytochemistry 40: 961-965
12. Weniger, B., Italiano, L., Beck, J. P., Bastida, J., Bergoñón, S., Codina, C., Lobstein, A., Anton, R. (1995) Cytotoxic activity of Amaryllidaceae alkaloids. Planta Med. 61: 77-79