Cardiovascular activity of the crude alkaloidal fraction from Tabernaemontana pandacaqui in the rat

Journal of Ethnopharmacology

Volumn 59, Issue 3, 1998, Pages 131-137

  Taesotikul, T ^a   Panthong, A ^a   Kanjanapothi, D ^a   Verpoorte, R ^b   Scheffer, J J C ^b  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Bradycardia activity; Crude alkaloidal fraction; Hypotension; Tabernaemontana pandacaqui

Indexed keywords

ACETYLCHOLINE; ALKALOID; ANTIHYPERTENSIVE AGENT; ATROPINE; BIOGENIC AMINE; CARDIOVASCULAR AGENT; CHLORPHENIRAMINE; HISTAMINE; PENTOBARBITAL; RESERPINE; TABERNAEMONTANA PANDACAQUI EXTRACT;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; BRADYCARDIA; CENTRAL NERVOUS SYSTEM; CHOLINERGIC SYSTEM; CONTROLLED STUDY; FEMALE; HEART RATE; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; RAT; SPINAL ANIMAL; SYSTOLIC BLOOD PRESSURE;

ADJUVANTS, ANESTHESIA; ALKALOIDS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CHLORPHENIRAMINE; HEART RATE; PENTOBARBITAL; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; RESERPINE;

EID: 0031965362     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(97)00116-5     Document Type: Article

References (6)

1. Burkhalter, A., Julius, D., Frick, O.L., 1995. Histamine, serotonin, and the ergot alkaloids. In: Katzung, B.G. (Ed.), Basic and Clinical Pharmacology, 6th ed. Appleton and Lange, East Norwalk, USA, p. 263.
2. Gillespie J.S., Muir T.C. A method of stimulating the complete sympathetic outflow from the spinal cord to blood vessels in the pithed rats. British Journal of Pharmacology. 30:1967;78-87.
3. Taesotikul T., Panthong A., Kanjanpothi D., Verpoorte R., Scheffer J.J.C. Cardiovascular effects of Tabernaemontana pandacaqui Poir. Journal of Ethnopharmacology. 27(1-2):1989;107-119.
4. Tsiang, Y., Li, P.T., 1977. Flora Republicae Popularis Sinicae, vol. 63. Kexue Chubanshe, Beijng, pp. 98, 119.
5. Macmillan W.H. A hypothesis concerning the effects of cocaine on the action of sympathomimetic amines. British Journal of Pharmacology. 14:1959;385-391.
6. van Beek T.A., Verpoorte R., Baerheim-Svendsen A. Tabernaemontana (Apocynaceae): a review of its taxonomy, phytochemistry, ethnobotany and pharmacology. Journal of Ethnopharmacology. 10:1984;1-156.