A proposed biochemical mechanism for citric acid accumulation by Aspergillus niger Yang No. 2 growing in solid state fermentation

World Journal of Microbiology and Biotechnology

Volumn 16, Issue 3, 2000, Pages 271-275

  Leangon, S ^a,b   Maddox, I S ^a   Brooks, J D ^a  

^a MASSEY UNIVERSITY   (New Zealand)

^b BURAPHA UNIVERSITY   (Thailand)

Author keywords

Adenylates; Aspergillus niger; ATP:citrate lyase; Citric acid; Oxalic acid

Indexed keywords

ADENOSINE TRIPHOSPHATE CITRATE LYASE; BIOACCUMULATION; CITRIC ACID; CYTOSOL; ENZYME ACTIVITY; ENZYME INHIBITION; FUNGAL MUTANT; GENETIC STRAIN; ISOCITRATE DEHYDROGENASE; MICROBE METABOLISM; MITOCHONDRION; MYCELIUM; OXALIC ACID; SOLID STATE FERMENTATION;

ASPERGILLUS NIGER;

EID: 0033910334     PISSN: 09593993     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008980816610     Document Type: Article

References (24)

1. Bradford, M.M. 1976 A rapid and sensitive method for the quantification of protein, utilizing the principle of protein-dye binding. Analytical Biochemistry 72, 248-254.
2. Brooke, A.G. 1994 Industrial fermentation and Aspergillus citric acid. In The Genus Aspergillus: from Taxonomy and Genetics to Industrial Application, eds Powell, K.A., Renwick, A. & Peberdy, J.F. pp. 129-134. FEBS Symposium No. 69, Plenum Press, New York. ISBN 0306447010.
3. Burlina, A. 1985 2-Oxoglutarate. In Methods of Enzymatic Analysis, Vol. VII, eds Bergmeyer, J. & Grassl, M. pp. 20-24. Verlag Chemie, Weinheim. ISBN 3527260471.
4. Feir, H.A. & Suzuki, I. 1969 Pyruvate carboxylase of Aspergillus niger: kinetic study of a biotin-containing carboxylase. Canadian Journal of Biochemistry 47, 698-710.
5. Heinz, F. & Kohlbecker, G. 1985 Oxalate. In Methods of Enzymatic Analysis, Vol. VII, eds Bergmeyer, J. & Grassl, M. pp. 649-656. Verlag Chemie, Weinheim. ISBN 3527260471.
6. Jaklitsch, W.M., Kubicek, C.P. & Scrutton, M.C. 1991 Intracellular location of enzymes involved in citrate production by Aspergillus niger. Canadian Journal of Microbiology 37, 823-827.
7. Jaworek, D. & Welsch, J. 1985 Adenosine 5′-diphosphate and adenosine 5′-monophosphate. In Methods of Enzymatic Analysis, Vol. VII, eds Bergmeyer, J. & Grassl, M. pp. 365-369. Verlag Chemie, Weinheim. ISBN 3527260471.
8. Jernejc, K., Perdih, A. & Cimermen, A. 1991 ATP:citrate lyase and carnitine acetyltransferase activity in a citric-producing Aspergillus niger strain. Applied Microbiology and Biotechnology 36, 92-95.
9. Kubicek, C.P. & Rohr, M. 1978 The role of the tricarboxylic acid cycle in citric acid accumulation by Aspergillus niger. European Journal of Applied Microbiology and Biotechnology 4, 263-271.
10. Kubicek, C.P., Schreferl-Kunar, G., Wohrer, W. & Rohr, M. 1988 Evidence for a cytoplasmic pathway of oxalate biosynthesis in Aspergillus niger. Applied and Environmental Microbiology 54, 633-637.
11. Kubicek, C.P., Witteveen, C.F.B. & Visser, J. 1994 Regulation of organic acid production by Aspergilli. In The Genus Aspergillus: from Taxonomy and Genetics to Industrial Application. eds Powell, K.A., Renwick, A. & Peberdy, J.F. pp. 135-145. FEBS Symposium No. 69, Plenum Press, New York. ISBN 0306447010.
12. La Nauze, J.A. 1966 Aconitase and isocitrate dehydrogenase of A. niger in relation to citric acid production. Journal of General Microbiology 44, 73-81.
13. Leangon, S., Maddox, I.S. & Brooks, J.D. 1999 Influence of the glycolytic rate on production of citric and oxalic acid by Aspergillus niger in solid state fermentation. World Journal of Microbiology and Biotechnology 15, 493-495.
14. Lenz, H., Wunderwald, P. & Eggerer, H. 1976 Partial purification and some properties of oxaloacetase from Aspergillus niger. European Journal of Biochemistry 65, 225-236.
15. Lu, M.Y., Maddox, I.S. & Brooks, J.D. 1995 Citric acid production by Aspergillus niger in solid substrate fermentation. Bioresource Technology 54, 235-239.
16. Lu, M.Y., Brooks, J.D. & Maddox, I.S. 1997 Citric acid production by solid state fermentation in a packed bed reactor using Aspergillus niger. Enzyme and Microbial Technology 21, 392-397.
17. Meixner-Monori, B., Kubicek, C.P., Harrer, W., Schreferl, G. & Rohr, M. 1986 NADP-specific isocitrate dehydrogenase from the citric acid-accumulating fungus Aspergillus niger. Biochemical Journal 236, 549-557.
18. Mitsushima, K., Shinmyo, A. & Enatsu, T. 1978 Control of citrate and 2-oxoglutatate formation in Candida lipolytica mitochondria by adenine nucleotides. Biochimica et Biophysica Acta 538, 481-492.
19. Mollering, H. 1985 Citrate. In Methods of Enzymatic Analysis, Vol. VII, eds Bergmeyer, J. & Grassl, M. pp. 2-12. Verlag Chemie, Weinheim. ISBN 3527260471.
20. Purohit, H.J. & Ratledge, C. 1988 Mitochondrial location of pyruvate carboxylase in Aspergillus niger. FEMS Microbiology Letters 55, 129-132.
21. Reed, L.J. & Mukherjee, B.B. 1969 α-Ketoglutarate dehydrogenase complex from Escherichia coli. In Methods in Enzymology, Vol. 13, Citric Acid Cycle, ed. Lowenstein, J.M. pp. 55-61. Academic Press, New York.
22. Rej, R. 1985 Oxaloacetate. In Methods of Enzymatic Analysis, Vol. VII, eds Bergmeyer, J. & Grassl, M. pp. 55-66. Verlag Chemie, Weinheim. ISBN 3527260471.
23. Takeda, Y., Suzuki, F. & Inoue, H. 1969 Reactions leading to and from the cycle. In Methods in Enzymology, Vol. 13, Citric Acid Cycle, ed. Lowenstein, J.M. p. 27. Academic Press, New York.
24. Trautschold, I., Lamprecht, W. & Schweitzer, G. 1985 Adenosine 5′-triphosphate: UV-method with hexokinase and glucose-6-phosphate dehydrogenase. In Methods of Enzymatic Analysis, Vol. VII, eds Bergmeyer, J. & Grassl, M. pp. 346-357. Verlag Chemie, Weinheim. ISBN 3527260471.