메뉴 건너뛰기




Volumn 11, Issue 5, 2000, Pages 283-293

Pharmacokinetics and metabolism of reboxetine

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CYTOCHROME P450; DEXTROMETHORPHAN; DIMETHYLNITROSAMINE DEMETHYLASE; FLUOXETINE; KETOCONAZOLE; LORAZEPAM; NORADRENALIN UPTAKE INHIBITOR; QUINIDINE; REBOXETINE;

EID: 0033909461     PISSN: 09548602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (5)

References (32)
  • 1
    • 0032869942 scopus 로고    scopus 로고
    • No effect of the new antidepressant reboxetine on CYP2D6 activity in healthy volunteers
    • Avenoso A, Facciolà G, Scordo MG, Spina E. No effect of the new antidepressant reboxetine on CYP2D6 activity in healthy volunteers. Ther Drug Monit 1999; 21: 577-579.
    • (1999) Ther Drug Monit , vol.21 , pp. 577-579
    • Avenoso, A.1    Facciolà, G.2    Scordo, M.G.3    Spina, E.4
  • 2
    • 0031979755 scopus 로고    scopus 로고
    • Metabolism of the newer antidepressants: An overview of the pharmacological and pharmacokinetic implications
    • Caccia S. Metabolism of the newer antidepressants: an overview of the pharmacological and pharmacokinetic implications. Drug Dispos 1998; 34: 281-302.
    • (1998) Drug Dispos , vol.34 , pp. 281-302
    • Caccia, S.1
  • 3
    • 0026037163 scopus 로고
    • Comparison of the disposition and of the metabolic pattern of reboxetine, a new antidepressant, in the rat, dog, monkey and man
    • Cocchiara G, Battaglia R, Pevarello P, Strolin Benedetti M. Comparison of the disposition and of the metabolic pattern of reboxetine, a new antidepressant, in the rat, dog, monkey and man. Eur J Drug Metab Pharmacokinet 1991; 16: 231-239.
    • (1991) Eur J Drug Metab Pharmacokinet , vol.16 , pp. 231-239
    • Cocchiara, G.1    Battaglia, R.2    Pevarello, P.3    Strolin Benedetti, M.4
  • 4
    • 0032747406 scopus 로고    scopus 로고
    • Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat
    • Connor TJ, Kelliher P, Harkin A, Kelly JP, Leonard BE. Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat. Eur J Pharmacol 1999; 379: 125-133.
    • (1999) Eur J Pharmacol , vol.379 , pp. 125-133
    • Connor, T.J.1    Kelliher, P.2    Harkin, A.3    Kelly, J.P.4    Leonard, B.E.5
  • 5
    • 0033668766 scopus 로고    scopus 로고
    • Pharmacokinetics of single-dose reboxetine in volunteers with renal insufficiency
    • in press
    • Coulomb F, Ducret F, Fiorentini F et al. Pharmacokinetics of single-dose reboxetine in volunteers with renal insufficiency. J Clin Pharmacol 2000; in press.
    • (2000) J Clin Pharmacol
    • Coulomb, F.1    Ducret, F.2    Fiorentini, F.3
  • 8
    • 0032424283 scopus 로고    scopus 로고
    • Differential pharmacology of the newer antidepressants
    • DeVane CL. Differential pharmacology of the newer antidepressants. J Clin Psychiatry 1998; 59 (Suppl 20): 85-93.
    • (1998) J Clin Psychiatry , vol.59 , Issue.SUPPL. 20 , pp. 85-93
    • DeVane, C.L.1
  • 9
    • 0030909396 scopus 로고    scopus 로고
    • Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor
    • Dostert P, Benedetti MS, Pogessi I. Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor. Eur Neuropsychopharmacol 1997; 7 (Suppl 1): S23-S35.
    • (1997) Eur Neuropsychopharmacol , vol.7 , Issue.SUPPL. 1
    • Dostert, P.1    Benedetti, M.S.2    Pogessi, I.3
  • 10
    • 0029094439 scopus 로고
    • Pharmacokinetics of reboxetine in healthy volunteers. Single oral doses, linearity and plasma protein binding
    • Edwards DM, Pellizzoni C, Breuel HP et al. Pharmacokinetics of reboxetine in healthy volunteers. Single oral doses, linearity and plasma protein binding. Biopharm Drug Dispos 1995; 16: 443-460.
    • (1995) Biopharm Drug Dispos , vol.16 , pp. 443-460
    • Edwards, D.M.1    Pellizzoni, C.2    Breuel, H.P.3
  • 12
    • 0030906294 scopus 로고    scopus 로고
    • Pharmacokinetics of reboxetine, a new selective noradrenaline uptake inhibitor, in patients with various degrees of hepatic and renal insufficiency
    • Fiorentini F, Poggesi I, Januzzo MG, Duchene P, Strolin Benedetti M. Pharmacokinetics of reboxetine, a new selective noradrenaline uptake inhibitor, in patients with various degrees of hepatic and renal insufficiency. Pharmacol Res 1997; 35: 239.
    • (1997) Pharmacol Res , vol.35 , pp. 239
    • Fiorentini, F.1    Poggesi, I.2    Januzzo, M.G.3    Duchene, P.4    Strolin Benedetti, M.5
  • 13
    • 0032779771 scopus 로고    scopus 로고
    • Evaluation of the potential pharmacokinetic/pharmacodynamic interaction between fluoxetine and reboxetine in healthy volunteers
    • Fleishaker JC, Herman BD. Pearson LK, Ionita A, Mucci M. Evaluation of the potential pharmacokinetic/pharmacodynamic interaction between fluoxetine and reboxetine in healthy volunteers. Clin Drug Invest 1999a; 18: 141-150.
    • (1999) Clin Drug Invest , vol.18 , pp. 141-150
    • Fleishaker, J.C.1    Herman, B.D.2    Pearson, L.K.3    Ionita, A.4    Mucci, M.5
  • 14
    • 0032899823 scopus 로고    scopus 로고
    • Absolute bioavailability of reboxetine enantiomers and effect of gender on pharmacokinetics
    • Fleishaker JC, Mucci M, Pellizzoni C, Poggesi I. Absolute bioavailability of reboxetine enantiomers and effect of gender on pharmacokinetics. Biopharm Drug Dispos 1999b; 20: 53-57.
    • (1999) Biopharm Drug Dispos , vol.20 , pp. 53-57
    • Fleishaker, J.C.1    Mucci, M.2    Pellizzoni, C.3    Poggesi, I.4
  • 15
    • 0006311362 scopus 로고    scopus 로고
    • Lack of effect of reboxetine on electrocardiographic parameters in healthy volunteers
    • Fleishaker JC, Francom SF, Herman BD, Azie NE. Lack of effect of reboxetine on electrocardiographic parameters in healthy volunteers. Clin Pharmacol Ther 2000; 67: 109.
    • (2000) Clin Pharmacol Ther , vol.67 , pp. 109
    • Fleishaker, J.C.1    Francom, S.F.2    Herman, B.D.3    Azie, N.E.4
  • 16
    • 0032822782 scopus 로고    scopus 로고
    • The role of norepinephrine in the treatment of depression
    • Gorman JM, Nemeroff CB. The role of norepinephrine in the treatment of depression. J Clin Psychiatry 1999; 60: 623-631.
    • (1999) J Clin Psychiatry , vol.60 , pp. 623-631
    • Gorman, J.M.1    Nemeroff, C.B.2
  • 17
    • 0032698156 scopus 로고    scopus 로고
    • Ketoconazole inhibits the clearance of the enantiomers of the antidepressant reboxetine in humans
    • Herman BD, Fleishaker JC, Brown MT. Ketoconazole inhibits the clearance of the enantiomers of the antidepressant reboxetine in humans. Clin Pharmacol Ther 1999; 66: 374-379.
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 374-379
    • Herman, B.D.1    Fleishaker, J.C.2    Brown, M.T.3
  • 19
    • 0000184324 scopus 로고
    • Pharmacokinetics of reboxetine in healthy volunteers of different ages
    • Jannuzzo MG, Ryde M, Karlmark B et al. Pharmacokinetics of reboxetine in healthy volunteers of different ages. Eur Neuropsychopharmacol 1995a; 5: 300.
    • (1995) Eur Neuropsychopharmacol , vol.5 , pp. 300
    • Jannuzzo, M.G.1    Ryde, M.2    Karlmark, B.3
  • 22
    • 0021236980 scopus 로고
    • Potential antidepressant agents, α-Aryloxy-benzyl derivatives of ethanolamine and morpholine
    • Melloni P, Carniel G, della Torre A et al. Potential antidepressant agents, α-Aryloxy-benzyl derivatives of ethanolamine and morpholine. Eur J Med Chem Chim Thér 1984; 19: 235-242.
    • (1984) Eur J Med Chem Chim Thér , vol.19 , pp. 235-242
    • Melloni, P.1    Carniel, G.2    Della Torre, A.3
  • 25
  • 27
    • 0024533417 scopus 로고
    • Effect of reboxetine, a new antidepressant drug, on the central noradrenergic system: Behavioural and biochemical studies
    • Riva M, Brunello N, Rovescalli AC et al. Effect of reboxetine, a new antidepressant drug, on the central noradrenergic system: behavioural and biochemical studies. J Drug Dev 1989; 1: 243-253.
    • (1989) J Drug Dev , vol.1 , pp. 243-253
    • Riva, M.1    Brunello, N.2    Rovescalli, A.C.3
  • 30
    • 0028880829 scopus 로고
    • Stereoselective and species-dependent kinetics of reboxetine in mouse and rat
    • Strolin Benedetti M, Frigerio E, Tocchetti P et al. Stereoselective and species-dependent kinetics of reboxetine in mouse and rat. Chirality 1995; 7: 285-289.
    • (1995) Chirality , vol.7 , pp. 285-289
    • Strolin Benedetti, M.1    Frigerio, E.2    Tocchetti, P.3
  • 31
    • 0033063549 scopus 로고    scopus 로고
    • Reboxetine, a unique selective NRI, prevents relapse and recurrence in long-term treatment of major depressive disorder
    • Versiani M, Mehilane L, Gaszner P, Arnaud-Castiglioni R. Reboxetine, a unique selective NRI, prevents relapse and recurrence in long-term treatment of major depressive disorder. J Clin Psychiatry 1999; 60: 400-406.
    • (1999) J Clin Psychiatry , vol.60 , pp. 400-406
    • Versiani, M.1    Mehilane, L.2    Gaszner, P.3    Arnaud-Castiglioni, R.4
  • 32
    • 0032750751 scopus 로고    scopus 로고
    • 450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes
    • 450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes. Drug Metab Dispos 1999: 27: 1334-1340.
    • (1999) Drug Metab Dispos , vol.27 , pp. 1334-1340
    • Wienkers, L.C.1    Allievi, C.2    Hauer, M.J.3    Wynalda, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.